LOINC
Version 2.67

88452-8Babesia microti 18S rRNA gene [Presence] in Blood by NAA with non-probe detectionActive

Part Description

LP264278-5   Babesia microti 18S rRNA gene
Babesia microti is a parasite that invades human red blood cells and is transmitted by the Ixodid scapularis tick. Infection by the Babesia species was first discovered in Croatia in 1957, but has proven to exist across the world in the last fifty years. B. microti is the most common babesiosis parasite in the United States. It was first discovered in the Northeast, but has spread to counties of the lower Hudson River Valley of New York State and on to the upper Midwest. Thirty-five patients were reported to be infected with B. microti by the Minnesota Department of Health in 2009. The Babesia parasites possess vesicles that secrete enzymes that facilitates its entrance into the host erythrocytes. They reproduces asexually in red blood cells and sexually in the Ixodid scapularis tick. Infection with Babesia leads to a wide range and severity of symptoms. Symptoms that are characterized as mild to moderate include fever, fatigue, chills, sweats, headache, myalgia, anorexia cough, arthralgia and nausea. Symptoms of severe illness are seen most often in patients who are immunosuppressed due to infections like Human immunodeficiency virus and conditions such as cancer. Severe symptoms of Babesia infection include respiratory failure, disseminated intravascular coagulation, congestive heart failure, liver and renal failure, and splenic infarction. There are several ways to diagnose infections with Babesia including thick and thin smear analysis, polymerase chain reaction, indirect immunofluorescence antibody, and by injecting patient blood into a hamster and waiting for severe parasitemia to develop in 2-4 weeks. Treatment of Babesia infection is with antibiotics or exchange transfusion when the parasite load in the blood becomes very high. [PMID: 18755385] [https://academic.oup.com/cid/article/64/11/1622/3067352/Possible-TransfusionTransmitted-Babesia] [PMID: 22170915] Source: Regenstrief LOINC

Fully-Specified Name

Component
Babesia microti 18S rRNA gene
Property
PrThr
Time
Pt
System
Bld
Scale
Ord
Method
Non-probe.amp.tar

Additional Names

Short Name
B microti 18S rRNA Bld Ql NAA+non-probe
Display Name
B. microti 18S rRNA gene NAA+non-probe Ql (Bld)

Basic Attributes

Class
MICRO
Type
Laboratory
First Released
Version 2.64
Last Updated
Version 2.64
Order vs. Observation
Both

Example Answer List LL360-9

Source: Regenstrief Institute

Answer Code Score Answer ID
Positive Copyright http://snomed.info/sct ID:10828004 Positive (qualifier value) LA6576-8
Negative Copyright http://snomed.info/sct ID:260385009 Negative (qualifier value) LA6577-6

Member of these Panels

LOINC Long Common Name
88461-9 Babesia microti and B. divergens+MO-1 and B. duncani 18S rRNA gene panel - Blood by NAA with non-probe detection

Member of these Groups

LG41637-6 Babesia

Language Variants Get Info

zh-CNChinese (CHINA)
鼠源巴贝斯虫 18S rRNA 基因:存在情况或阈值:时间点:全血:序数型:非探针法.基因扩增.靶向
fr-FRFrench (FRANCE)
Babesia microti ARNr 18S gène:Présence/Seuil:Ponctuel:Sang:Qualitatif:Non-PCR amplification de cible
es-ESSpanish (SPAIN)
Gen rRNA 18S Babesia microti:PrThr:Punto temporal:Sangre:Ord:Amplificación del objetivo no basado en sonda

LOINC FHIR® API Example - CodeSystem Request Get Info

https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=88452-8