88715-8
Norquetiapine [Mass/volume] in Serum or Plasma by Confirmatory method
Active
Part Description
LP265314-7 Norquetiapine
Norquetiapine is the primary active metabolite of the parent drug quetiapine and is used to treat bipolar depression, major depressive episodes, and generalized anxiety disorder. Norquetiapine, unlike quetiapine but similar to some other antidepressants, prevents the reuptake of norepinephrine (NE) at the noradrenaline transporter (NET). The NET is a protein on the surface of noradrenergic neurons that controls the activity of NE by transporting it into the cytoplasm of the noradrenergic neurons. Norquetiapine partially activates the 5-HT1A receptors which, with the NET, is thought to have antidepressant responses in the patient. Quetiapine and norquetiapine act together against several target receptors, including NET, 5-HT1A, and 5-HT2, to treat antidepressant and anxiolytic symptoms of patients. [http://onlinelibrary.wiley.com/doi/10.1111/j.1471-4159.2006.03717.x/pdf] PMID: 26436896
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- Norquetiapine
- Property
- MCnc
- Time
- Pt
- System
- Ser/Plas
- Scale
- Qn
- Method
- Confirm
Additional Names
- Long Common Name
- Norquetiapine [Mass/volume] in Serum or Plasma by Confirmatory method
- Short Name
- Norquetiapine SerPl Cfm-mCnc
- Display Name
- Norquetiapine Confirm [Mass/Vol]
- Consumer Name Alpha Get Info
- Norquetiapine, Blood
Basic Attributes
- Class
- DRUG/TOX
- Type
- Laboratory
- First Released
- Version 2.64
- Last Updated
- Version 2.64 (ADD)
- Order vs. Observation
- Both
Language Variants Get Info
Tag | Language | Translation |
---|---|---|
de-AT | German (Austria) | Synonyms: Norquetiapin |
el-GR | Greek (Greece) | Νορκετιαπίνη: Synonyms: MCnc Νορκετιαπίνη |
es-ES | Spanish (Spain) | Norquetiapina: Synonyms: Cuantitativo |
es-MX | Spanish (Mexico) | Norquetiapina: |
fr-FR | French (France) | Norquétiapine: |
it-IT | Italian (Italy) | Norquetiapina: Synonyms: Concentrazione di Massa Livelli farmacologici e tossicologia Plasma Punto nel tempo (episodio) Siero Siero o Plasma |
zh-CN | Chinese (China) | 去甲基喹硫平: Synonyms: 去甲基奎的平; |
Example Units
Unit | Source |
---|---|
ng/mL | Example UCUM Units |
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