Version 2.78

Term Description

This panel of terms was developed by, but not limited to, Oncimmune. Elevated levels of the autoantibodies in this panel against lung tumor proteins are present in 40% of lung cancer patients at the time the malignancy is diagnosed. This panel of six autoantibodies is used to assist in the early diagnosis of lung cancer in patients at high risk of developing it, either because of risk factors such as smoking or the presence of a nodule on a CT scan. PMID: 21733826
Source: Regenstrief LOINC

Part Description

LP266490-4   Lung cancer antibody panel
Lung cancer has the highest mortality of all cancers across the world. Survival rates are much improved if the cancer is diagnosed and treated before the malignant cells have metastasized. Patients diagnosed with stage 1 lung cancer experience a 5-year survival rate of 52% which increases to 87.5% if platinum-based chemotherapy is part of the treatment. While computed tomography (CT) scans are the gold standard for diagnosing lung cancer, CT has a 50% rate of false positives and, subsequently, a large number of unnecessary follow-up treatments. An immunoassay has been developed that measures autoantibodies to lung cancer related antigens in the peripheral blood and may help lower the false positive rates of CT scans. These antibodies include CAGE, GBU4-5, NY-ESO-1, p53, SOX-2, MAGE A4, and HuD and one or more of them are present in 40% of patients at the time lung cancer is diagnosed. Which antibodies are positive may in the future provide a clue to what subtype of lung cancer the patient has developed. Ongoing studies are investigating the utility of the antibodies being used as biomarkers for lung cancer in high risk asymptomatic patients. There is also research investigating the changes in an individual's lung cancer antibody profile from their baseline values to predict early lung cancer development. PMID: 21733826 Source: Regenstrief LOINC

Panel Hierarchy

Details for each LOINC in Panel LHC-Forms

LOINC Name R/O/C Cardinality Example UCUM Units
88863-6 Lung cancer antibody panel - Serum or Plasma by Immunoassay
Indent89001-2 CAGE Ab [Units/volume] in Serum or Plasma by Immunoassay [arb'U]/mL
Indent89002-0 GBU4-5 Ab [Units/volume] in Serum or Plasma by Immunoassay [arb'U]/mL
Indent89003-8 HuD Ab [Units/volume] in Serum or Plasma by Immunoassay [arb'U]/mL
Indent89004-6 MAGE A4 Ab [Units/volume] in Serum or Plasma by Immunoassay [arb'U]/mL
Indent89005-3 NY-ESO-1 Ab [Units/volume] in Serum or Plasma by Immunoassay [arb'U]/mL
Indent89006-1 p53 Ab [Units/volume] in Serum or Plasma by Immunoassay [arb'U]/mL
Indent89007-9 SOX-2 Ab [Units/volume] in Serum or Plasma by Immunoassay [arb'U]/mL
Indent89041-8 Lung cancer antibody [Interpretation] in Serum or Plasma by Immunoassay

Fully-Specified Name

Component
Lung cancer antibody panel
Property
-
Time
Pt
System
Ser/Plas
Scale
-
Method
IA

Additional Names

Short Name
Lung cancer antibody panel SerPl IA
Display Name
Lung cancer antibody panel IA
Consumer Name Alpha Get Info
Lung cancer antibody panel, Blood

Basic Attributes

Class
PANEL.SERO
Type
Laboratory
First Released
Version 2.64
Last Updated
Version 2.64
Order vs. Observation
Order
Panel Type
Panel

Language Variants Get Info

Tag Language Translation
es-ES Spanish (Spain) Perfil de anticuerpos contra el cáncer de pulmón:Propiedades mixtas (sólo paneles):Punto temporal:Suero o Plasma:-:IA
es-MX Spanish (Mexico) Panel de anticuerpos contra el cáncer de pulmón:-:Punto temporal:Suero o Plasma:-:Inmunoensayo
fr-FR French (France) Cancer du poumon anticorps panel:-:Ponctuel:Sérum/Plasma:-:Immunoanalyse
it-IT Italian (Italy) Cancro al polmone, panel anticorpi:-:Pt:Siero/Plasma:-:IA
Synonyms: Anticorpi cancro al polmone Immunoassay Panel anticorpi cancro al polmone Plasma Punto nel tempo (episodio) Set di prescrizione sierologia Siero Siero o Plasma Sierologia (anticorpi e la maggior parte degli ant
zh-CN Chinese (China) 肺癌抗体组套:-:时间点:血清/血浆:-:免疫测定法
Synonyms: 免疫测定;免疫分析法;免疫检定法;免疫检定;免疫试验;酶免疫测定法;酶免疫测定;酶免疫分析法;酶免疫检定法;酶免疫检定;酶免疫试验 医嘱套餐 医嘱套餐类 医嘱套餐组 医嘱组 医嘱组.血清学;实验室组套（组合、医嘱组、套餐、套餐医嘱、医嘱套餐、组合申请、组合项目）类.血清学试验;医嘱组.血清学检验项目;医嘱组.血清学试验;医嘱组类.血清学;医嘱组类.血清学检验项目;医嘱组类.血清学试验;实验室医嘱组类.血清学;实验室医嘱组类.血清学检验项目;血清学医嘱组;血清学医嘱组类 医嘱组合 医嘱组合类 医嘱组套 医嘱组套类 医嘱组类 多重;多重型;多重标尺类型;多重精度类型 套餐 套餐医嘱 套餐医嘱组 套餐医嘱组类 实验室医嘱套餐 实验室医嘱套餐类 实验室医嘱组 实验室医嘱组合类 实验室医嘱组套 实验室医嘱组套类 实验室套餐医嘱组 实验室套餐医嘱组类 实验室检验项目医嘱组合类 实验室检验项目组合类 时刻;随机;随意;瞬间 检验医嘱组合类 检验项目医嘱组合类 检验项目组合类 癌 组 组合 组合医嘱 组合类 组套 肺癌Ab 肺癌抗体组套（组合、医嘱组、套餐、套餐医嘱、医嘱套餐、组合申请、组合项目） 血清;血清学;血清学检验项目;血清学检验项目 (非微生物学);血清学检验项目（非微生物学）;血清学检验项目类;血清学检验项目类 (非微生物学);血清学类;血清学类检验项目;血清学类检验项目 (非微生物学);血清学类试验;血清学类试验 (非微生物学);血清学试验;血清学试验 (非微生物学);血清学试验（非微生物学）;血清学试验类 (非微生物学);血清类 血清或血浆

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=88863-6
Questionnaire definition
https://fhir.loinc.org/Questionnaire/?url=http://loinc.org/q/88863-6