Version 2.78

Term Description

A descreased ratio of eiscospentaenoate/arachidonate is a well recognized predictor of cardiovascular disease. PMID: 24976364
Source: Regenstrief LOINC

Part Descriptions

LP33077-6   Eicosapentaenoate
Eicosapentaenoate (EPA) is a long chain omega-3 fatty acid that is present throughout the body including in cell membranes. EPA is found in fatty fish including salmon, tuna, mackerel, sardines, shellfish, and herring. EPA can be biosynthesized from alpha-linolenic acid (ALA), but it is much more efficient to increase levels by including EPA-rich sources in one's diet. EPA has anti-inflammatory properties that are vital to fetal development and the process of healthy aging. Its anti-inflammatory effects are due to reduced gene expression of genes involved in inflammatory and atherogenesis-related pathways, thereby lowering the risk of cardiovascular disease. EPA has also been found to increase platelet stability, decrease endothelial activation, and improve vascular permeability. Taking EPA supplements leads to an increased amount of EPA in the plaque of carotid arteries which may decrease inflammation and increase plaque stability. PMID: 22332096 Many other studies have been run that show acorrelation between higher plasma levels of EPA and reduced symptoms of disease, some of which include Alzheimer's disease, depression, rheumatoid arthritis, and Raynaud Syndrome.[ http://pennstatehershey.adam.com/content.aspx?productId=107&pid=33&gid=000301] Source: Regenstrief LOINC

LP69948-5   Arachidonate
Arachidonate (AA) is an essential polyunsaturated omega-6 fatty acid that is produced from dietary linoleic acid. AA is located in human fat, liver, brain, and glandular organs and is a mediator of inflammation. The AA within the phospholipids of cell membranes is the surface where the production of a number of biologically active compounds occurs. A few of the compounds produced includes prostaglandins, thromboxanes, and leukotrienes which regulate processes including platelet aggregation, blood clotting, smooth muscle contraction, leukocyte chemotaxis, inflammatory cytokine production, and immune function.[PubChem: 444899] AA is released from the cell membrane when acted upon by phospholipases and then metabolized by cyclooxygenase (COX) producing the prostanoids prostaglandin and thromboxane A2, which can stimulate or mitigate inflammation. PMID: 21508345 One of the benefits of the Omega-3 fatty acids for patients with inflammatory disease is believed to be their selective modification of the metabolism of AA by the omega-3 fatty acids that results in a reduced amount of inflammation. PMID: 23371504 Source: Regenstrief LOINC

Fully-Specified Name

Component
Eicosapentaenoate/Arachidonate
Property
SRto
Time
Pt
System
Ser/Plas
Scale
Qn
Method

Additional Names

Short Name
EPA/AA SerPl-sRto
Display Name
EPA/Arachidonate (C20:4w6) [Molar ratio]
Consumer Name Alpha Get Info
EPA/Arachidonate (C20:4w6), Blood

Basic Attributes

Class
CHEM
Type
Laboratory
First Released
Version 2.64
Last Updated
Version 2.73
Order vs. Observation
Both
Common Test Rank Get Info
14063

Member of these Panels

LOINC Long Common Name
88884-2 Fatty acid omega-3 and omega-6 panel - Serum or Plasma

Language Variants Get Info

Tag Language Translation
es-ES Spanish (Spain) Eicosapentaenoato(C20:5w3)/Araquidonato:Relacion de Sustancia:Punto temporal:Suero o Plasma:Qn:
Synonyms: Cuantitativo
es-MX Spanish (Mexico) Eicosapentaenoato / Araquidonato:Proporción de sustancia:Punto temporal:Suero o Plasma:Cuantitativo:
fr-CA French (Canada) Eicosapentanoate/Arachidonate:Ratio de substance:Temps ponctuel:Sérum/Plasma:Quantitatif:
fr-BE French (Belgium) Eicosapentanoate/Arachidonate:Ratio de substance:Temps ponctuel:Sérum/Plasma:Quantitatif:
fr-FR French (France) Eicosapentaénoate/arachidonate:Moles ratio:Ponctuel:Sérum/Plasma:Numérique:
it-IT Italian (Italy) Eicosapentaenoato/Arachidonato:Srto:Pt:Siero/Plasma:Qn:
Synonyms: Arachidato (C20:0) Arachidonato (C20:4w6) Chimica Eicosapentaenoato (C20:5w3) Plasma Punto nel tempo (episodio) Rapporto di sostanza Siero Siero o Plasma
nl-NL Dutch (Netherlands) eicosapentaenoaat/arachidonaat:molaire verhouding:moment:serum of plasma:kwantitatief:
Synonyms: arachidonzuur
ru-RU Russian (Russian Federation) Эйкозапентаеноат/Арахидонат:МольОтн:ТчкВрм:Сыв/Плаз:Колич:
Synonyms: Арахидонат (C20:0) Количественный Мольная доля;Молярная доля;Отношение концентраций Плазма Сыворотка Сыворотка или Плазма Точка во времени;Момент Эйкозапентаеноат (C20:5w3)
tr-TR Turkish (Turkey) Eikozapentaenoat/Araşidonat:SOrn:Zmlı:Ser/Plaz:Kant:
Synonyms: SubsOranı
zh-CN Chinese (China) 二十碳五烯酸/花生四烯酸:物质的量比率:时间点:血清/血浆:定量型:
Synonyms: 5,8,11,14-二十碳四烯酸;AA;Arch acid;C20:4w6;花生四烯酸（Arachidonic acid，AA）;花生四烯酸, C20:4w6;花生脂酸;花生脂酸, C20:4w6 C20:5w3;EPA;二十碳五烯酸（Eicosapentaenoic acid，EPA）;二十碳五烯酸, C20:5w3;二十碳双烯酸;附子脂酸;附子脂酸, C20:5w3 化学;化学检验项目;化学检验项目类;化学类;化学试验;非刺激耐受型化学检验项目;非刺激耐受型化学检验项目类;非刺激耐受型化学试验;非刺激耐受型化学试验类 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 时刻;随机;随意;瞬间 物质的量比值;物质的量比;摩尔比;摩尔比率;摩尔比值 花生四烯酸 (C20:0) 血清或血浆

Example Units

Unit Source
mol/mol Example UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=88996-4