Version 2.78

Part Description

LP266154-6   Zopiclone-N-oxide
Zopiclone-N-oxide is one of two metabolites of eszopiclone and is not pharmacologically active.[http://www.who.int/medicines/areas/quality_safety/4.6ZopicloneCritReview.pdf] Eszopiclone is a cyclopyrrolones and a benzodiazepine receptor agonist derived from pyridine, pyrazine and piperazine and used to treat insomnia. Its mechanism of action is to bind to the omega-1 subtype of the alpha subunit of gamma-aminobutyrate-benzodiazepine GABA receptor complex (GABA-A). GABA-A is a chloride ionophore in the central nervous system, that when bound causes the chloride channels to open, leading to hyperpolarization, inhibition of neuronal firing, and an increase in the inhibition of GABA. This sequence of events causes an hypnotic response in the patient and induces sleep. Eszopiclone has insignificant anxiolytic activity and shows no evidence of causing increased liver enzymes in the blood.[CID 969472] Source: Regenstrief LOINC

Fully-Specified Name

Component
Zopiclone-N-oxide
Property
MCnc
Time
Pt
System
Urine
Scale
Qn
Method

Additional Names

Short Name
Zopiclone-N-oxide Ur-mCnc
Display Name
Zopiclone-N-oxide (U) [Mass/Vol]
Consumer Name Alpha Get Info
Zopiclone-N-oxide, Urine

Basic Attributes

Class
DRUG/TOX
Type
Laboratory
First Released
Version 2.64
Last Updated
Version 2.73
Order vs. Observation
Both
Common Test Rank Get Info
16546

Language Variants Get Info

Tag Language Translation
es-ES Spanish (Spain) Zopiclona-N-óxido:Concentración de masa:Punto temporal:Orina:Qn:
Synonyms: Cuantitativo
es-MX Spanish (Mexico) Zopiclona-N-óxido:Concentración de masa:Punto temporal:Orina:Cuantitativo:
fr-FR French (France) Zopiclone-N-oxyde:Masse/Volume:Ponctuel:Urine:Numérique:
it-IT Italian (Italy) Zopiclone-N-Ossido:MCnc:Pt:Urine:Qn:
Synonyms: Concentrazione di Massa Livelli farmacologici e tossicologia Punto nel tempo (episodio)
zh-CN Chinese (China) N-氧化佐匹克隆:质量浓度:时间点:尿液:定量型:
Synonyms: Imovane;Zopiclone;吡嗪哌酯;吡嗪哌酯（安眠药）;唑比酮;安眠镇静药物;忆梦返;环吡咯酮衍生物 N 型 佐匹克隆-N-氧化物;佐匹克隆N-氧化物;艾司佐匹克隆杂质A;右佐匹克隆相关物质A;氧化佐匹克隆;CAS 43200-96-0;EINECS 200-659-6 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 尿;小便;下泉 时刻;随机;随意;瞬间 毒品 毒品类 水平;浓度;质量浓度(单位体积) 药品类 药物 药物/毒理学;药物/毒理学试验;药物毒理学试验;药物毒理学试验类 药物类

Example Units

Unit Source
ng/mL Example UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=89043-4