LOINC
Version 2.72

89307-3Naloxone-3-glucuronide [Presence] in Urine by Screen methodActive

Part Description

LP266980-4   Naloxone-3-glucuronide
Naloxone is a pure opioid antagonist and, when taken at recommended doses, has no physiological effects in the absence of an opioid agonist. Intravenous naloxone becomes effective within two minutes of injection, but oral or sublingual naloxone has little effect due to its poor absorption. Therefore, intravenous naloxone is used to treat opioid overdose, and it is used as a sublingual combination with buprenorphine, an opioid agonist-antagonist used to treat chronic opioid-dependence, to lower buprenorphine's abuse potential as follows: when the combination is taken sublingually as prescribed, naloxone exerts little effect and buprenorphine's effects predominate; however, if crushed and injected intravenously, naloxone's antagonist properties reverse the agonist effects of buprenorphine and can precipitate withdrawal. [PMID:19368419] Nalaxone levels along with its inactive metabolite, naloxone-3-glucuronide (N3G), may be measured to monitor compliance or identify illicit opioid drug use. Source: Regenstrief LOINC, PMID: 19368419

Fully-Specified Name

Component
Naloxone-3-glucuronide
Property
PrThr
Time
Pt
System
Urine
Scale
Ord
Method
Screen

Additional Names

Short Name
Naloxone-3G Ur Ql Scn
Display Name
Naloxone-3-glucuronide Screen Ql (U)
Consumer Name Alpha
Naloxone-3-glucuronide, Urine

Example Answer List LL744-4

Source: Regenstrief Institute

Answer Code Score Answer ID
Detected LA11882-0
Not detected LA11883-8

Basic Attributes

Class
DRUG/TOX
Type
Laboratory
First Released
Version 2.64
Last Updated
Version 2.70
Order vs. Observation
Observation

Member of these Panels

LOINC Long Common Name
95796-9 Opioids panel - Urine by Screen method

Language Variants Get Info

zh-CNChinese (China)
钠洛酮-3-葡糖苷酸:存在情况或阈值:时间点:尿液:序数型:毒理学筛查试验
fr-FRFrench (France)
Naloxone-3-glucuronide:Présence/Seuil:Ponctuel:Urine:Qualitatif:Dépistage
it-ITItalian (Italy)
Naloxone-3-glucuronide:PrThr:Pt:Urine:Ord:Screening
es-MXSpanish (Mexico)
Naloxona-3-glucurónido:Presencia o umbral:Punto temporal:Orina:Ordinal:Pantalla de toxicología
es-ESSpanish (Spain)
Naloxona-3-glucurónido:PrThr:Punto temporal:Orina:Ord:Cribado toxicológico

LOINC FHIR® API Example - CodeSystem Request Get Info

https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=89307-3