Version 2.78

Part Description

LP266980-4   Naloxone-3-glucuronide
Naloxone is a pure opioid antagonist and, when taken at recommended doses, has no physiological effects in the absence of an opioid agonist. Intravenous naloxone becomes effective within two minutes of injection, but oral or sublingual naloxone has little effect due to its poor absorption. Therefore, intravenous naloxone is used to treat opioid overdose, and it is used as a sublingual combination with buprenorphine, an opioid agonist-antagonist used to treat chronic opioid-dependence, to lower buprenorphine's abuse potential as follows: when the combination is taken sublingually as prescribed, naloxone exerts little effect and buprenorphine's effects predominate; however, if crushed and injected intravenously, naloxone's antagonist properties reverse the agonist effects of buprenorphine and can precipitate withdrawal. PMID: 19368419 Nalaxone levels along with its inactive metabolite, naloxone-3-glucuronide (N3G), may be measured to monitor compliance or identify illicit opioid drug use. Source: Regenstrief LOINC, PMID: 19368419

Fully-Specified Name

Component
Naloxone-3-glucuronide
Property
PrThr
Time
Pt
System
Urine
Scale
Ord
Method
Screen

Additional Names

Short Name
Naloxone-3G Ur Ql Scn
Display Name
Naloxone-3-glucuronide Screen Ql (U)
Consumer Name Alpha Get Info
Naloxone-3-glucuronide, Urine

Example Answer List: LL744-4

Source: Regenstrief Institute
Answer Code Score Answer ID
Detected LA11882-0
Not detected LA11883-8

Basic Attributes

Class
DRUG/TOX
Type
Laboratory
First Released
Version 2.64
Last Updated
Version 2.70
Order vs. Observation
Observation

Member of these Panels

LOINC Long Common Name
95796-9 Opioids panel - Urine by Screen method

Language Variants Get Info

Tag Language Translation
es-ES Spanish (Spain) Naloxona-3-glucurónido:PrThr:Punto temporal:Orina:Ord:Cribado toxicológico
es-MX Spanish (Mexico) Naloxona-3-glucurónido:Presencia o umbral:Punto temporal:Orina:Ordinal:Pantalla de toxicología
fr-FR French (France) Naloxone-3-glucuronide:Présence/Seuil:Ponctuel:Urine:Qualitatif:Dépistage
it-IT Italian (Italy) Naloxone-3-glucuronide:PrThr:Pt:Urine:Ord:Screening
Synonyms: Livelli farmacologici e tossicologia Presenza o Soglia Punto nel tempo (episodio) Screening tossicologico
zh-CN Chinese (China) 钠洛酮-3-葡糖苷酸:存在情况或阈值:时间点:尿液:序数型:毒理学筛查试验
Synonyms: Ⅲ C19H21NO4;纳洛酮;那诺松 III 三 依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型 叁 存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值） 尿;小便;下泉 时刻;随机;随意;瞬间 毒品 毒品类 筛查 筛查方法;筛查法;筛查试验 筛查试验 筛选试验 纳洛酮-3-葡糖苷酸;那诺松-3-葡糖苷酸 药品类 药物 药物/毒理学;药物/毒理学试验;药物毒理学试验;药物毒理学试验类 药物类 葡萄糖醛酸甙 葡萄糖醛酸苷 过筛 过筛试验

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=89307-3