Part Descriptions

LP19061-8   Cells.CD45RA
CD45 (also known as leukocyte common antigen) is a tyrosine phosphatase specific to hematopoietic cells that is necessary for efficient T and B cell antigen receptor signal transduction. Multiple CD45 isoforms can be generated by alternative splicing of the A, B and C extracellular domains. In humans, naive T lymphocytes express CD45RA, which includes the A domain, and activated T lymphocytes express CD45RO, which does not contain A, B or C. PMID: 16423560 CD45RB and RC are not as well-understood in humans as CD45RA and RO, but peripheral T cells that express CD45RA have also been found to express high levels of CD45RB, whereas CD45RO cells do not PMID: 15020649, and high levels of CD45RC expression on CD8+ T cells may be predictive of acute kidney graft rejection in transplant patients. PMID: 23894540 Source: Regenstrief LOINC

LP14443-3   CD4
Found on helper T-cells; weakly expressed on monocytes.
Associated with some mature T-cell neoplasms, including most cases of T-cell CLL/prolymphocytic leukemia, peripheral
T-cell lymphoma, adult T-cell leukemia/lymphoma and Sézary syndrome/mycosis fungoides Source: Regenstrief LOINC

LP20086-2   CD45RA
Found on Naive helper T-cells, B-cells and Granulocytes
Associated with some T-cell lymphomas and some mature B-cell lymphomas Source: Regenstrief LOINC

LOINC Names Get Info

Fully-Specified Name
Cells.CD45RA/Cells.CD4:NFr:Pt:Bld:Qn:
Long Common Name
CD45RA cells/CD4 cells in Blood
Short Name
CD45RA Cells/CD4 Cells NFr Bld
Display Name
CD45RA cells/CD4 cells (Bld)
Consumer Name Alpha Get Info
CD45RA cells/CD4 Cells, Blood

Part Model Get Info

  • Component
    Cells.CD45RA/Cells.CD4
    LP445232-4
    • Analyte
      Cells.CD45RA/Cells.CD4
      LP445232-4
      • Component Numerator
        Cells.CD45RA
        LP19061-8
        • Component Numerator Core
          Cells.CD45RA
          LP19061-8
        • Component Numerator Core Suffix
          NULL
           
      • Component Denominator
        Cells.CD4
        LP70340-2
        • Component Denominator Core
          Cells.CD4
          LP70340-2
        • Component Denominator Core Suffix
          NULL
           
    • Challenge
      NULL
       
    • Adjustment
      NULL
       
    • Count
      NULL
       
  • Property
    NFr
    LP6838-9
  • Time
    Pt
    LP6960-1
  • System
    Bld
    LP7057-5
    • System Core
      Bld
      LP7057-5
    • Super System
      NULL
       
  • Scale
    Qn
    LP7753-9
  • Method
    NULL
     

Basic Attributes

Class
CELLMARK
Type
Laboratory
First Released
Version 2.64
Last Updated
Version 2.79 (NAM)
Change Reason
Release 2.79: COMPONENT: Triggered by Coll w SCT: This is a specific fraction case where the denominator is percentage or /100. Because the logic is that the percentage piece is captured by Property: NFr (Numeric Fraction), and by Unit: %, therefore, it is redundant to include "100" in the component;
Order vs. Observation
Both

Member of these Panels

LOINCLong Common Name
96493-2T-cell naive and memory and activated subsets panel - Blood

Language Variants Get Info

TagLanguageTranslation
cs-CZCzech (Czechia)Buňky.CD45RA/100 buněk.CD4:Početní podíl:Časový bod:Krev:Kvantitativní:
el-GRGreek (Greece)Κύτταρα.CD45RA/Κύτταρα.CD4:NFr:Pt:Αίμα:Qn:
Synonyms: CD4 CELLMARK NFr Pt Qn Αίμα Κύτταρα Κύτταρα.CD4 Κύτταρα.CD45RA
es-ESSpanish (Spain)Células CD45RA/Células CD4:Fracción numérica:Punto temporal:Sangre:Qn:
Synonyms: Cuantitativo
es-MXSpanish (Mexico)Cells.CD45RA / 100 Cells.CD4:Fracción numérica:Punto temporal:Sangre:Cuantitativo:
et-EEEstonian (Estonia)Rakud.CD45RA/rakud.CD4:NFr:Pt:B:Qn:
Synonyms: Juhuslik Kvantitatiivne Veri
fr-CAFrench (Canada)Cellules.CD45RA/Cellules.CD4:Fraction numérique:Temps ponctuel:Sang:Quantitatif:
fr-FRFrench (France)CD45RA/CD4:Fraction de nombres:Ponctuel:Sang:Numérique:
fr-BEFrench (Belgium)Cellules.CD45RA/Cellules.CD4:Fraction numérique:Temps ponctuel:Sang:Quantitatif:
it-ITItalian (Italy)Cellule.CD45RA/Cellule.CD4:NFr:Pt:Sangue:Qn:
Synonyms: Cellule CD4 Cellule CD45RA Frazione numerica Modelli di superficie cellulare Punto nel tempo (episodio) Sangue
nl-NLDutch (Netherlands)cellen.CD45RA/cellen.CD4:getalsfractie:moment:bloed:kwantitatief:
pl-PLPolish (Poland)Komórki.CD45RA/limfocyty T CD4+:frakcja liczbowa:punkt w czasie:krew:ilościowy:
Synonyms: CD4 Komórki CD4 Komórki CD45RA
ru-RURussian (Russian Federation)Клетки.CD45RA/Клетки.CD4:КолДоля:ТчкВрм:Кр:Колич:
Synonyms: Количественный Количество отношение Кровь Точка во времени;Момент
tr-TRTurkish (Turkey)Hücreler.CD45RA/Hücreler.CD4:SayFr:Zmlı:Kan:Kant:
zh-CNChinese (China)细胞.CD45RA/细胞.CD4:计数型分数:时间点:全血:定量型:
Synonyms: CD45RA CD45RA细胞 CD4细胞 L3T4 Leu18 Leu-18 Leu3 Leu-3 T4 T-4 W3/25 发现于原态辅助 T-细胞、B-细胞以及粒细胞之上。与一些 T-细胞淋巴瘤和一些成熟 B-细胞淋巴瘤相关。 发现于辅助 T-细胞;微弱表达于单核细胞。与相关。一些成熟 T-细胞肿瘤,包括大多数情况下的 T-细胞慢性淋巴细胞白血病/前淋巴细胞白血病、外周 T-细胞淋巴瘤、成人 T-细胞白血病/淋巴瘤以及 Sézary 综合征(T 细胞红皮病)/蕈样肉芽肿(mycosis fungoides)。 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 数量型分数;数量或计数型分数;数量型分数或计数型分数 时刻;随机;随意;瞬间 细胞含量;细胞性;细胞性质;细胞构成;细胞类 细胞标志物 血;血液 诱导 T 细胞 诱导性 T 细胞 辅助 T 细胞 辅助诱导 T 细胞 辅助诱导物 T 细胞

Example Units

UnitSource
%Example UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=89360-2