Version 2.80

Part Description

LP266352-6   von Willebrand factor.ristocetin cofactor inhibitor
Von Willebrand disease (VWD) is caused by either a qualitative or quantitative deficit of the multimeric glycoprotein known as von Willebrand factor (VWF). VWD affects 1-2% of the world population, making it the most common inherited bleeding disorder. VWF plays a crucial role in primary hemostasis by triggering platelet adhesion to injured vessel walls and promoting platelet aggregation. VWF also protects factor VIII from premature degradation in the peripheral circulation. To diagnose VWD, there are several tests that must be run including ristocetin cofactor activity, VWF antigen quantitative assay, Factor VIII activity, and collagen binding assay. Additional tests are needed to determine the subtype of VWD. The ristocetin cofactor activity can be measured using platelet aggregation or platelet agglutination. Both of these assays measure the agglutination of platelets by VWF in the presence of ristocetin. When anti-VWF antibodies bind to the epitope of VWF the ability of VWF to aggregate platelets to the area of injury is compromised. Patients who are most likely to develop anti-VWF include patients with complete or partial VWF gene deletions, patients who have received multiple transfusions, and patients with a family history of developing anti-VWF antibodies. PMID: 28804849 PMID: 21186048 PMID: 23297130 Source: Regenstrief LOINC

Fully-Specified Name

Component
von Willebrand factor.ristocetin cofactor inhibitor
Property
ACnc
Time
Pt
System
PPP
Scale
Qn
Method
Coag

Additional Names

Long Common Name
von Willebrand factor.ristocetin cofactor inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
Short Name
vWF.ristocetin cofactor inhibitor PPP
Display Name
vWf.ristocetin cofactor inhibitor Coag Qn (PPP)
Consumer Name Alpha Get Info
vWf.ristocetin cofactor inhibitor, Blood

Basic Attributes

Class
COAG
Type
Laboratory
First Released
Version 2.64
Last Updated
Version 2.68 (MIN)
Order vs. Observation
Both

Language Variants Get Info

Tag Language Translation
de-AT German (Austria) Synonyms: vWF:RiCoF Inhibitor
el-GR Greek (Greece) παράγοντας Von Willebrand.αναστολέας συμπαράγοντα ριστοσετίνης:ACnc:Pt:PPP:Qn:Coag
Synonyms: ACnc παράγοντας Von Willebrand παράγοντας Von Willebrand.αναστολέας συμπαράγοντα ριστοσετίνης παράγοντας Von Willebrand.συμπαράγοντας ριστοσετίνης Ριστοσετίνη
es-ES Spanish (Spain) Factor Von Willebrand. Cofactor inhibidor de ristocetina:Concentración arbitraria:Punto temporal:Plasma pobre en plaquetas:Qn:Coagulativo
Synonyms: Cuantitativo
es-MX Spanish (Mexico) Factor von Willebrand inhibidor del cofactor de ristocetina:Concentración arbitraria:Punto temporal:Plasma pobre en plaquetas:Cuantitativo:Ensayo de coagulación
fr-FR French (France) Facteur Willebrand inhibiteur cofacteur ristocétine:Arbitraire/Volume:Ponctuel:Plasma pauvre en plaquettes:Numérique:Coagulation
it-IT Italian (Italy) von Willebrand, fattore.inibitore cofattore ristocetina:ACnc:Pt:PPP:Qn:Coag
Synonyms: Cofattore ristocetina del fattore di von Willebran Concentrazione Arbitraria Fattore di von Willebrand (vWf) Inibitore del cofattore ristocetina del fattore di Plasma povero di piastrine Punto nel tempo (episodio) Studio di coagulazione Test di coagulazione
zh-CN Chinese (China) von Willebrand 因子.瑞斯托菌素辅助因子抑制剂:任意型浓度:时间点:贫血小板血浆:定量型:凝血功能分析
Synonyms: von Willebrand von Willebrand 因子（von Willebrand Factor，vWf）;vWf;vWf 因子;血管性假血友病因子;血管性血友病因子 von Willebrand 因子（vWf 因子、血管性假血友病因子、血管性血友病因子）.瑞斯托菌素辅助因子（利托菌素辅助因子、瑞斯托菌素辅因子、瑞斯托霉素辅助因子、瑞斯西丁素辅助因子、Ristocetin 因子） 抑制剂（抑制因子、抑制物） von willebrand因子（vWf 因子、血管性假血友病因子、血管性血友病因子）.瑞斯托菌素辅助因子;von willebrand因子.瑞斯托菌素辅助因子（利托菌素辅助因子、瑞斯托菌素辅因子、瑞斯托霉素辅助因子、瑞斯西丁素辅助因子、Ristocetin 因子）;vWf 因子瑞斯托菌素辅助因子 乏血小板血浆;Platelet poor plasma;PPP 任意型浓度(单位体积);任意浓度;单位体积的任意单位数;人工型浓度 倾斜试管;倾斜试管法;凝固测定;凝血功能测定;凝血测定;快速凝固试验;快速凝血试验;快速凝集试验 冯·威勒布兰德 冯威勒布兰德 冯威勒布兰德氏 凝血功能;凝血功能试验;凝血过程;血液凝固;血液凝固功能;血液凝固过程 利托菌素;瑞斯托霉素;瑞斯西丁素;瑞期托菌素;Ristocetin 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 因素 抑制因子 抑制物 抑制物质 时刻;随机;随意;瞬间 系数 辅因子

Example Units

Unit Source
[beth'U]/mL Example UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=89367-7