89431-1

CD25 cells/CD4 cells in Blood

Active

Part Descriptions

LP17753-2 Cells.CD25
CD25 is the alpha chain of the IL-2 receptor. CD25 is a type I transmembrane protein present on activated T cells, activated B cells, some thymocytes, myeloid precursors, and oligodendrocytes that associates with CD122 to form a heterodimer that can act as a high-affinity receptor for IL-2. It has been found that a large proportion of resting memory T cells constitutively express CD25 in humans. CD25 is expressed in most B-cell neoplasms, some acute nonlymphocytic leukemias, neuroblastomas, and tumor infiltrating lymphocytes. sIL-2R is its soluble form, and may be elevated in these diseases and has been used to monitor disease progression. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, CD25

LP14443-3 CD4
Found on helper T-cells; weakly expressed on monocytes.
Associated with some mature T-cell neoplasms, including most cases of T-cell CLL/prolymphocytic leukemia, peripheral
T-cell lymphoma, adult T-cell leukemia/lymphoma and Sézary syndrome/mycosis fungoides Source: Regenstrief LOINC

LOINC Names Get Info

Fully-Specified Name: Cells.CD25/Cells.CD4:NFr:Pt:Bld:Qn:
Long Common Name: CD25 cells/CD4 cells in Blood
Short Name: CD25 Cells/CD4 Cells NFr Bld
Display Name: CD25 cells/CD4 cells (Bld)
Consumer Name Alpha Get Info: CD25 cells/CD4 Cells, Blood

Part Model Get Info

Component
Cells.CD25/Cells.CD4
LP445085-6
- Analyte
  Cells.CD25/Cells.CD4
  LP445085-6
  - Component Numerator
    Cells.CD25
    LP17753-2
    - Component Numerator Core
      Cells.CD25
      LP17753-2
    - Component Numerator Core Suffix
      NULL
  - Component Denominator
    Cells.CD4
    LP70340-2
    - Component Denominator Core
      Cells.CD4
      LP70340-2
    - Component Denominator Core Suffix
      NULL
- Challenge
  NULL
- Adjustment
  NULL
- Count
  NULL
Property
NFr
LP6838-9
Time
Pt
LP6960-1
- Time Core
  Pt
  LP6960-1
- Time Modifier
  NULL
System
Bld
LP7057-5
- System Core
  Bld
  LP7057-5
- Super System
  NULL
Scale
Qn
LP7753-9
Method
NULL

Basic Attributes

Class: CELLMARK
Type: Laboratory
First Released: Version 2.64
Last Updated: Version 2.79 (NAM)
Change Reason: Release 2.79: COMPONENT: Triggered by Coll w SCT: This is a specific fraction case where the denominator is percentage or /100. Because the logic is that the percentage piece is captured by Property: NFr (Numeric Fraction), and by Unit: %, therefore, it is redundant to include "100" in the component;
Order vs. Observation: Both

Member of these Panels

LOINC	Long Common Name
96493-2	T-cell naive and memory and activated subsets panel - Blood

Language Variants Get Info

Tag	Language	Translation
cs-CZ	Czech (Czechia)	Buňky.CD25/100 buněk.CD4:Početní podíl:Časový bod:Krev:Kvantitativní:
el-GR	Greek (Greece)	Κύτταρα.CD25/Κύτταρα.CD4:NFr:Pt:Αίμα:Qn: Synonyms: CD25 CD4 CELLMARK NFr Pt Qn Αίμα Κύτταρα Κύτταρα.CD25 Κύτταρα.CD4
es-ES	Spanish (Spain)	Células CD25+/Células CD4:Fracción numérica:Punto temporal:Sangre:Qn: Synonyms: Cuantitativo
es-MX	Spanish (Mexico)	Cells.CD25 / 100 Cells.CD4:Fracción numérica:Punto temporal:Sangre:Cuantitativo:
et-EE	Estonian (Estonia)	Rakud.CD25/rakud.CD4:NFr:Pt:B:Qn: Synonyms: Juhuslik Kvantitatiivne Veri
fr-CA	French (Canada)	Cellules.CD25/Cellules.CD4:Fraction numérique:Temps ponctuel:Sang:Quantitatif:
fr-FR	French (France)	CD25/CD4:Fraction de nombres:Ponctuel:Sang:Numérique:
fr-BE	French (Belgium)	Cellules.CD25/Cellules.CD4:Fraction numérique:Temps ponctuel:Sang:Quantitatif:
it-IT	Italian (Italy)	Cellule.CD25/Cellule.CD4:NFr:Pt:Sangue:Qn: Synonyms: Cellule CD25 Cellule CD4 Frazione numerica Modelli di superficie cellulare Punto nel tempo (episodio) Sangue
nl-NL	Dutch (Netherlands)	cellen.CD25/cellen.CD4:getalsfractie:moment:bloed:kwantitatief:
pl-PL	Polish (Poland)	Komórki.CD25/limfocyty T CD4+:frakcja liczbowa:punkt w czasie:krew:ilościowy: Synonyms: CD25 CD4 Komórki CD25 Komórki CD4
ru-RU	Russian (Russian Federation)	Клетки.CD25/Клетки.CD4:КолДоля:ТчкВрм:Кр:Колич: Synonyms: Количественный Количество отношение Кровь Точка во времени;Момент
tr-TR	Turkish (Turkey)	Hücreler.CD25/Hücreler.CD4:SayFr:Zmlı:Kan:Kant:
zh-CN	Chinese (China)	细胞.CD25/细胞.CD4:计数型分数:时间点:全血:定量型: Synonyms: CD25细胞 CD4细胞 IL-2 受体 Alpha 链;IL-2 受体α链;IL-2R;IL-2R Tac 抗原;ILR2;Tac 抗原 L3T4 Leu3 Leu-3 T4 T-4 W3/25 发现于辅助 T-细胞；微弱表达于单核细胞。与相关。一些成熟 T-细胞肿瘤，包括大多数情况下的 T-细胞慢性淋巴细胞白血病/前淋巴细胞白血病、外周 T-细胞淋巴瘤、成人 T-细胞白血病/淋巴瘤以及 Sézary 综合征（T 细胞红皮病）/蕈样肉芽肿（mycosis fungoides）。可用数量表示的;定量性;数值型;数量型;连续数值型标尺数量型分数;数量或计数型分数;数量型分数或计数型分数时刻;随机;随意;瞬间细胞含量;细胞性;细胞性质;细胞构成;细胞类细胞标志物血;血液诱导 T 细胞诱导性 T 细胞辅助 T 细胞辅助诱导 T 细胞辅助诱导物 T 细胞

Example Units

Unit	Source
%	Example UCUM Units

LOINC Terminology Service (API) using HL7^® FHIR^® Get Info

CodeSystem lookup: https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=89431-1

LOINC Copyright

Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.