89500-3

Sulfatide IgG Ab [Presence] in Serum by Line blot

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Term Description

This term was created for, but is not limited in use to, the submitter's test strip, a membrane strip pre-coated with a specific set of antigens in parallel lines. If antibodies to any of those antigens are present in the patient's serum, they will bind to the specific antigen. The bound patient antibodies are then detected using labelled anti-human antibodies. Manufacturers call this method by different names, including immunoblot, line blot, and line immunoassay. LOINC uses the immunoblot (IB) method to mean that some electrophoretic/chromatographic separation occurs such that position (size) of the band is part of the assessment (as in Western blot). Because this assay does not involve a separation step but rather uses strips with pre-fixed antigens, the LOINC Method for this term is Line blot.

Part Description

LP14905-1 Sulfatide
Anti-sulfatide autoantibodies, also known as anti-GalS, have been associated with a variety of nervous system disorders, including IgM paraproteinaemia with associated demyelinating neuropathy, sensory impairment, and inflammatory demyelinating polyneuropathy (IDPN). Studies have shown the presence of GalS on the external surface of the myelin sheath, which suggests that anti-GalS auto-antibodies can induce immune demyelination and may play a role in the pathogenesis of motor neuropathies such as Guillain-Barre syndrome (GBS), and in fact, over 60% of GBS patients have been found to have anti-GalS antibodies. Some data show that patients presenting with high titer of anti-GalS antibodies could benefit from early treatment with plasmapheresis and/or intravenous immunoglobulin. PMID: 10762412 ] Source: Regenstrief LOINC, PMID: 10762412

LOINC Names Get Info

Fully-Specified Name: Sulfatide Ab.IgG:PrThr:Pt:Ser:Ord:Line blot
Long Common Name: Sulfatide IgG Ab [Presence] in Serum by Line blot
Short Name: Sulfatide IgG Ser Ql Line blot
Display Name: Sulfatide IgG Line blot Ql (S)
Consumer Name Alpha Get Info: Sulfatide IgG antibody, Blood

Part Model Get Info

Component
Sulfatide Ab.IgG
LP39934-2
- Analyte
  Sulfatide Ab.IgG
  LP39934-2
  - Component Numerator
    Sulfatide Ab.IgG
    LP39934-2
    - Component Numerator Core
      Sulfatide
      LP14905-1
    - Component Numerator Core Suffix
      Ab.IgG
      LP32401-9
  - Component Denominator
    NULL
    - Component Denominator Core
      NULL
    - Component Denominator Core Suffix
      NULL
- Challenge
  NULL
- Adjustment
  NULL
- Count
  NULL
Property
PrThr
LP217195-9
Time
Pt
LP6960-1
- Time Core
  Pt
  LP6960-1
- Time Modifier
  NULL
System
Ser
LP7567-3
- System Core
  Ser
  LP7567-3
- Super System
  NULL
Scale
Ord
LP7751-3
Method
Line blot
LP266806-1

Example Answer List: LL744-4

Source: Regenstrief Institute

Answer	Code	Score	Answer ID
Detected			LA11882-0
Not detected			LA11883-8

Basic Attributes

Class: SERO
Type: Laboratory
First Released: Version 2.64
Last Updated: Version 2.64 (ADD)
Order vs. Observation: Both

Member of these Groups Get Info

LOINC Group	Group Name
LG10912-0	Sulfatide Ab.IgG\|PrThr\|Pt\|ANYBldSerPl

Language Variants Get Info

Tag	Language	Translation
cs-CZ	Czech (Czechia)	Sulfatid IgG:Přítomnost nebo práh:Časový bod:Sérum:Ordinální:Line blot
de-DE	German (Germany)	Sulfatid Ak.IgG:Nachweis oder Schwellenwert:Zeitpunkt:Serum:Ordinal:Line-Blot
el-GR	Greek (Greece)	Σουλφατίδιο Αντισώματα IgG:PrThr:Pt:Ορός:Ord:Γραμμή κηλίδωσης Synonyms: Ord PrThr Pt SERO Ανοσοσφαιρίνη G Αντίσωμα Αντισώματα IgG Γραμμή κηλίδωσης Ορός Σουλφατίδιο
es-ES	Spanish (Spain)	Sulfátido IgG:PrThr:Punto temporal:Suero:Ord:Line blot
es-MX	Spanish (Mexico)	Sulfatide Ab.IgG:Presencia o umbral:Punto temporal:Suero:Ordinal:Mancha de línea
fr-FR	French (France)	Sulfatide Ac IgG:Présence/Seuil:Ponctuel:Sérum:Qualitatif:Blot en ligne
fr-CA	French (Canada)	Sulfatide, IgG:Présence-Seuil:Temps ponctuel:Sérum:Ordinal:Immunoessai sur bandelette
it-IT	Italian (Italy)	Sulfatide Ab.IgG:PrThr:Pt:Siero:Ord:Line blot Synonyms: anticorpi IgG anticorpo Presenza o Soglia Punto nel tempo (episodio) Siero Sierologia (anticorpi e la maggior parte degli ant
nl-NL	Dutch (Netherlands)	sulfatide As.IgG:aanwezigheid:moment:serum:ordinaal:lijnblot Synonyms: antistof; antilichaam
zh-CN	Chinese (China)	硫酸脑苷脂抗体.IgG:存在情况或阈值:时间点:血清:序数型:线点印迹法 Synonyms: Ab.IgG;IgG;抗体 IgG Ab;自身抗体依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型免疫球蛋白 G 存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值）时刻;随机;随意;瞬间硫脂 Ab 硫脂 Ab.IgG 硫脂;硫脑苷脂;硫苷脂;脑硫脂硫脂抗体硫脂抗体.IgG 硫脑苷脂 Ab 硫脑苷脂 Ab.IgG 硫脑苷脂抗体硫脑苷脂抗体.IgG 硫苷脂 Ab 硫苷脂 Ab.IgG 硫苷脂抗体硫苷脂抗体.IgG 硫酸脑苷脂 Ab 硫酸脑苷脂 Ab.IgG 硫酸脑苷脂 IgG 线点杂交技术;线点杂交法;线条状印迹法脑硫脂 Ab 脑硫脂 Ab.IgG 脑硫脂抗体脑硫脂抗体.IgG 血清;血清学;血清学检验项目;血清学检验项目 (非微生物学);血清学检验项目（非微生物学）;血清学检验项目类;血清学检验项目类 (非微生物学);血清学类;血清学类检验项目;血清学类检验项目 (非微生物学);血清学类试验;血清学类试验 (非微生物学);血清学试验;血清学试验 (非微生物学);血清学试验（非微生物学）;血清学试验类 (非微生物学);血清类

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LOINC Copyright

Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.