Version 2.78

Term Description

This term was created for, but is not limited in use to, the submitter's test strip, a membrane strip pre-coated with a specific set of antigens in parallel lines. If antibodies to any of those antigens are present in the patient's serum, they will bind to the specific antigen. The bound patient antibodies are then detected using labelled anti-human antibodies. Manufacturers call this method by different names, including immunoblot, line blot, and line immunoassay. LOINC uses the immunoblot (IB) method to mean that some electrophoretic/chromatographic separation occurs such that position (size) of the band is part of the assessment (as in Western blot). Because this assay does not involve a separation step but rather uses strips with pre-fixed antigens, the LOINC Method for this term is Line blot.
Source: Regenstrief LOINC

Part Descriptions

LP38249-6   Glomerular basement membrane Ab
Circulating glomerular basement membrane-specific antibodies are seen in Goodpasture syndrome; quantitation may be useful in monitoring treatment. This test is often used in conjunction with the antineutrophil cytoplasmic antibody (ANCA) test for Wegener granulomatosis and vasculitis. Source: LOINC partner 1

LP68423-0   Glomerular basement membrane
The layer of EXTRACELLULAR MATRIX that lies between the ENDOTHELIUM of the glomerular capillaries and the PODOCYTES of the inner or visceral layer of the BOWMAN CAPSULE. It is the product of these two cell types. It acts as a physical barrier and an ion-selective filter. Source: National Library of Medicine, MeSH 2006

LP68423-0   Glomerular basement membrane
The glomerular basement membrane is the basal laminal portion of the glomerulus which performs the actual filtration through the filtration slits between the podocytes, separating the blood on the inside from the filtrate on the outside. It is a fusion of the endothelial cell and podocyte basal laminas. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Wikepedia

Fully-Specified Name

Component
Glomerular basement membrane Ab
Property
PrThr
Time
Pt
System
Ser
Scale
Ord
Method
Line blot

Additional Names

Short Name
GBM Ab Ser Ql Line blot
Display Name
Glomerular basement membrane Ab Line blot Ql (S)
Consumer Name Alpha Get Info
Glomerular basement membrane antibody, Blood

Example Answer List: LL744-4

Source: Regenstrief Institute
Answer Code Score Answer ID
Detected LA11882-0
Not detected LA11883-8

Basic Attributes

Class
SERO
Type
Laboratory
First Released
Version 2.64
Last Updated
Version 2.64
Order vs. Observation
Both

Member of these Groups Get Info

LOINC Group Group Name
LG21457-3 Glomerular basement membrane Ab|PrThr|Pt|ANYBldSerPl

Language Variants Get Info

Tag Language Translation
es-ES Spanish (Spain) Membrana basal glomerular Anticuerpos:PrThr:Punto temporal:Suero:Ord:Line blot
es-MX Spanish (Mexico) Membrana basal glomerular Ab:Presencia o umbral:Punto temporal:Suero:Ordinal:Mancha de línea
fr-FR French (France) Membrane basale glomérulaire anticorps:Présence/Seuil:Ponctuel:Sérum:Qualitatif:Blot en ligne
fr-CA French (Canada) Membrane basale glomérulaire, Ac:Présence-Seuil:Temps ponctuel:Sérum:Ordinal:Immunoessai sur bandelette
it-IT Italian (Italy) Membrana basale glomerulare Ab:PrThr:Pt:Siero:Ord:Line blot
Synonyms: anticorpo MBG Presenza o Soglia Punto nel tempo (episodio) Siero Sierologia (anticorpi e la maggior parte degli ant
nl-NL Dutch (Netherlands) glomerulair basaal membraan As:aanwezigheid:moment:serum:ordinaal:lijnblot
Synonyms: antistof; antilichaam
zh-CN Chinese (China) 肾小球基底膜 抗体:存在情况或阈值:时间点:血清:序数型:线点印迹法
Synonyms: Ab;自身抗体 GBM 抗体 Goodpastures Goodpastures样综合征;Goodpastures病;肺出血-肾炎综合征;肾小球基底膜 依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型 基底膜 Ab 存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值） 小球 小球的 抗基底膜 抗肾小球基底膜 时刻;随机;随意;瞬间 线点杂交技术;线点杂交法;线条状印迹法 肾小球基底膜 Ab 肾小球基底膜抗体 肾小球基膜;Glomerular basement membrane;GBM 肾小球的 血清;血清学;血清学检验项目;血清学检验项目 (非微生物学);血清学检验项目（非微生物学）;血清学检验项目类;血清学检验项目类 (非微生物学);血清学类;血清学类检验项目;血清学类检验项目 (非微生物学);血清学类试验;血清学类试验 (非微生物学);血清学试验;血清学试验 (非微生物学);血清学试验（非微生物学）;血清学试验类 (非微生物学);血清类

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