89522-7

Ganglioside GM3 IgG Ab [Presence] in Serum by Line blot

Active

Term Description

This term was created for, but is not limited in use to, the submitter's test strip, a membrane strip pre-coated with a specific set of antigens in parallel lines. If antibodies to any of those antigens are present in the patient's serum, they will bind to the specific antigen. The bound patient antibodies are then detected using labelled anti-human antibodies. Manufacturers call this method by different names, including immunoblot, line blot, and line immunoassay. LOINC uses the immunoblot (IB) method to mean that some electrophoretic/chromatographic separation occurs such that position (size) of the band is part of the assessment (as in Western blot). Because this assay does not involve a separation step but rather uses strips with pre-fixed antigens, the LOINC Method for this term is Line blot.
Source: Regenstrief LOINC

Part Descriptions

LP99621-2   Ganglioside GM3
GM3 is a ganglioside found both within and outside the central nervous system. Anti-GM3 autoantibodies have been associated with Guillain-Barre syndrome, acute and isolated bulbar palsy, chronic ataxic neuropathy, chronic inflammatory demyelinating polyradiculoneuropathy and type 2 diabetes. [http://www.neurology-asia.org/articles/neuroasia-2013-18(3)-319.pdf] Source: Regenstrief LOINC,

LP222219-0   Ganglioside
A ganglioside molecule consists of a glycosphingolipid (ceramide and oligosaccharide) with one or more sialic acid residues linked to the sugar chain. Molecules with one sialic acid residue are called monosialogangliosides (GM), those with two are called disialogangliosides (GD), and those with three are trisialogangliosides (GT). Gangliosides without any sialic acid residues are called asialogangliosides, while those that do not have a ceramide N-acyl group are called lysogangliosides. The number that typically is included at the end of the name indicates the order in which the molecule was discovered. For example, GM2 is a ganglioside with one sialic acid residue that was the second GM to be identified. Source: Regenstrief LOINC

Fully-Specified Name

Component

Ganglioside GM3 Ab.IgG

Property

PrThr

Time

Pt

System

Ser

Scale

Ord

Method

Line blot

Additional Names

Short Name

GM3 IgG Ser Ql Line blot

Display Name

Ganglioside GM3 IgG Line blot Ql (S)

Consumer Name Alpha Get Info

Ganglioside GM3 IgG antibody, Blood

Example Answer List: LL744-4

Basic Attributes

Class

SERO

Type

Laboratory

First Released

Version 2.64

Last Updated

Version 2.64

Order vs. Observation

Both

Member of these Panels

Member of these Groups Get Info

Language Variants Get Info

Related Names

• ABS
• Aby
• Antby
• Anti
• Antibodies
• Antibody
• Autoantibodies
• Autoantibody
• Immune globulin G
• Immunoglobulin G
• Monosialoganglioside
• Ordinal
• Point in time
• PR
• QL
• Qual
• Qualitative
• Random
• Screen
• Serology
• Serum
• SR

LOINC Terminology Service (API) using HL7^® FHIR^® Get Info

Requests to this service require a free LOINC username and password. Below is a sample of the possible capabilities. See the LOINC Terminology Service documentation for more information.

CodeSystem lookup

https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=89522-7

LOINC Copyright

Copyright © 2024 Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © 1995-2024, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.