89579-7Troponin I.cardiac [Mass/volume] in Serum or Plasma by High sensitivity methodActive
Term Description
The "high sensitivity" troponin assays manufactured by different vendors have different analytical characteristics, including the limit of detection and 99% upper reference limit (URL). The quantitative results from different assays should not be compared to make clinical decisions, and reporting the quantitative result in isolation is not recommended. The troponin high sensitivity quantitative results should be reported with information about the assay and/or the interpretation, depending on the specific reporting method used in a given laboratory or hospital, that are included in the High sensitivity Troponin I [LOINC: 89577-1] and Troponin T [LOINC: 89576-3] panels.
1. The laboratory device 99th percentile upper reference limit [LOINC: 89581-3]
2. The laboratory device coefficient of variation at 99th percentile URL [LOINC: 89580-5]
3. The laboratory device detection limit [LOINC: 87706-8]
4. Interpretation for troponin T [LOINC: 89575-5] and/or troponin I [LOINC: 89578-9]
[PMID: 25204966]
Source: Regenstrief LOINC
Part Descriptions
LP14890-5 Troponin I.cardiac
Troponin I is a part of the troponin complex. It binds to actin in thin myofilaments to hold the actin-tropomyosin complex in place. Because of it myosin cannot bind actin in relaxed muscle. When calcium binds to the Troponin C it causes conformational changes which lead to dislocation of troponin I and finally tropomyosin leaves the binding site for myosin on actin leading to contraction of muscle. The letter I is given due to its inhibitory character.
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Source: Wikipedia, Wikipedia
LP14890-5 Troponin I.cardiac
The troponin test is used to help diagnose a heart attack, to detect and evaluate mild to severe heart injury, and to distinguish chest pain that may be due to other causes. Troponin values can remain high for 1–2 weeks after a heart attack. The test is not affected by damage to other muscles, so injections, accidents, and drugs that can damage muscle do not affect troponin levels. Troponin may rise following strenuous exercise, although in the absence of signs and symptoms of heart disease, it is usually of no medical significance.
Copyright Copyright © 2001-2019 American Association for Clinical Chemistry
Source: Lab Tests Online®, Lab Tests Online®
Fully-Specified Name
- Component
- Troponin I.cardiac
- Property
- MCnc
- Time
- Pt
- System
- Ser/Plas
- Scale
- Qn
- Method
- High sensitivity
Additional Names
- Short Name
- Troponin I SerPl HS-mCnc
- Display Name
- Troponin I.cardiac High sensitivity method [Mass/Vol]
Basic Attributes
- Class
- CHEM
- Type
- Laboratory
- First Released
- Version 2.64
- Last Updated
- Version 2.66
- Change Reason
- Updated Status from TRIAL to ACTIVE
- Order vs. Observation
- Observation
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 89577-1 | Troponin I.cardiac panel - Serum or Plasma by High sensitivity method |
Language Variants Get Info
- zh-CNChinese (CHINA)
- 肌钙蛋白 I.心脏:
质量浓度: 时间点: 血清/血浆: 定量型: 高灵敏度方法 - nl-NLDutch (NETHERLANDS)
- troponine I.hart:
massa/volume: moment: serum of plasma: kwantitatief: hoge gevoeligheid - et-EEEstonian (ESTONIA)
- Troponiin I.kardiaalne:
MCnc: Pt: S/P: Qn: Kõrgtundlik - fr-BEFrench (BELGIUM)
- Troponine I.cardiaque:
Concentration de masse: Temps ponctuel: Sérum/Plasma: Quantitatif: Sensibilité élevée - fr-CAFrench (CANADA)
- Troponine I.cardiaque:
Concentration de masse: Temps ponctuel: Sérum/Plasma: Quantitatif: Sensibilité élevée - fr-FRFrench (FRANCE)
- Troponine I cardiaque:
Masse/Volume: Ponctuel: Sérum/Plasma: Numérique: Ultrasensible - el-GRGreek (GREECE)
- Τροπονίνη Ι (καρδιακό ένζυμο):
Συγκέντρωση μάζας: Χρονική στιγμή: Ορός/Πλάσμα: Ποσοτική: Υψηλής ευαισθησίας - it-ITItalian (ITALY)
- Troponina I.cardiaca:
MCnc: Pt: Siero/Plasma: Qn: Elevata sensibilità - ru-RURussian (RUSSIAN FEDERATION)
- Тропонин I.сердечный:
МассКонц: ТчкВрм: Сыв/Плаз: Колич: Высокочувствительный - es-ESSpanish (SPAIN)
- Troponina I cardíaca:
Concentración de masa: Punto temporal: Suero o Plasma: Qn: Ultrasensible - tr-TRTurkish (TURKEY)
- Troponin I.kardiyak:
KütlKons: Zmlı: Ser/Plaz: Kant: Yüksek duyarlılık
Example Units
| Unit | Source |
|---|---|
| ng/L | Example UCUM Units |
LOINC FHIR® API Example - CodeSystem Request Get Info
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=89579-7
LOINC Copyright
Copyright © 2019 Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright