Version 2.78

Part Description

LP16650-1   Histoplasma capsulatum
Histoplasmosis capsulatum is a dimorphic fungal pathogen with filamentous or yeast forms,depending on nutritional factors and temperature.The M antigen is a well-known glycoprotein used as a diagnostic antigen for acute histoplasmosis as it induces the first precipitins during disease. Monoclonal antibodies (mAbs) to the M antigen have been found to modify the pathogenesis of histoplasmosis.Given the shortcomings of current therapies, the administration of mAbs is being investigated. PMID: 22347215 The H band is less commonly seen than the M band and is indicative of chronic or severe acute infections with H capsulatum.

H. capsulatum is found in nature primarily as a saprophytic mold. The mold form is comprised of hyaline septate hyphae, which produce two different asexual reproduction structures, macroconidia and microconidia. The micronidia are believed to be responsible for disease propagation since their 2-6 µm size is well suited for disposition into the distal alveoli. Infection is typically acquired through inhalation of fungal propagules upon disturbances of contaminated soil or excreta. Environmental and genetic factors influence disease manifestations which can range from asymptomatic or mild influenza-like disease to a disseminated sepsis form. Manifestations depend on the magnitude of exposure, the host's immunological status and the virulence of the infective strain. Reactivation of latent infection can result in significant disease, particularly for immunosuppressed individuals. Despite the availability of potent antifungal drugs, nearly one in ten patients hospitalized with histoplasmosis dies. PMID: 17223625 Source: Regenstrief LOINC

Fully-Specified Name

Component
Histoplasma capsulatum Ab
Property
Prid
Time
Pt
System
Ser/Plas
Scale
Nom
Method
Immune diffusion

Additional Names

Short Name
H capsul Ab SerPl ID
Display Name
H. capsulatum Ab Immune diff Nom
Consumer Name Alpha Get Info
Histoplasma capsulatum antibody, Blood

Preferred Answer List: LL5099-8

Source: Mayo Medical Laboratories
Answer Code Score Answer ID
M band present LA29407-6
H band present LA29408-4
H and M bands present LA29409-2
No band present LA29410-0

Basic Attributes

Class
MICRO
Type
Laboratory
First Released
Version 2.65
Last Updated
Version 2.73
Order vs. Observation
Both
Common Test Rank Get Info
10257

Member of these Panels

LOINC Long Common Name
90227-0 Histoplasma capsulatum H and M Ab panel - Serum

Language Variants Get Info

Tag Language Translation
es-ES Spanish (Spain) Histoplasma capsulatum Anticuerpos:Presencia o identidad:Punto temporal:Suero o Plasma:Nom:Inmunodifusión
es-MX Spanish (Mexico) Histoplasma capsulatum Ab:Presencia o identidad:Punto temporal:Suero o Plasma:Nominal:Difusión inmunitaria (ID)
fr-FR French (France) Histoplasma capsulatum Ac:Identification:Ponctuel:Sérum/Plasma:Résultat nominal:Immunodiffusion
fr-CA French (Canada) Histoplasma capsulatum, Ac:Présence ou identité:Temps ponctuel:Sérum/Plasma:Nominal:Immunodiffusion
fr-BE French (Belgium) Histoplasma capsulatum Ac:Présence ou identité:Temps ponctuel:Sérum/Plasma:Nominal:Immunodiffusion
Synonyms: Anticorps
it-IT Italian (Italy) Histoplasma capsulatum Ab:Prid:Pt:Siero/Plasma:Nom:Immuno diffusione
Synonyms: anticorpo Immuno diffusione (ID) Microbiologia Plasma Presenza o Identità Punto nel tempo (episodio) Siero Siero o Plasma
nl-NL Dutch (Netherlands) Histoplasma capsulatum As:identificator:moment:serum of plasma:nominaal:immunodiffusie
Synonyms: antistof; antilichaam
ru-RU Russian (Russian Federation) Histoplasma capsulatum Ат:ПрИд:ТчкВрм:Сыв/Плаз:Ном:Иммунодиффузия
Synonyms: Антитело Иммунодиффузия (ИД) Номинальный;Именной Плазма Присутствие или Идентификация Сыворотка Сыворотка или Плазма Точка во времени;Момент
tr-TR Turkish (Turkey) Histoplazma Kapsulatum Ab:MevcKimlik:Zmlı:Ser/Plaz:Snf:İmmün difüzyon
Synonyms: Ak
uk-UA Ukrainian (Ukraine) Histoplasma capsulatum Антитіла:Наявність або Ідентифікація:МоментЧасу:Сироватка/Плазма:Категорійно:Імунодифузія
Synonyms: ABS; Aby; Antby; Anti; Antibodies; Antibody; Autoantibodies; Autoantibody; H capsul; H capsulatum; H farciminosum; Histo; Histopl; Histoplasma farciminosum; Histoplasmos; Histoplasmosis; ID; Identity or presence; Imm; Immunodiff; Immunodiffusion; Imun; Imune; Infectious Disease; InfectiousDisease; Microbiology; Nominal; Pl; Plasma; Plsm; Point in time; Random; SerP; SerPl; SerPlas; Serum; Serum or plasma; SR
zh-CN Chinese (China) 荚膜组织胞浆菌 抗体:存在与否或特征标识:时间点:血清/血浆:名义型:免疫扩散法
Synonyms: Ab;自身抗体 免疫扩散 分类型应答;分类型结果;名义性;名称型;名词型;名词性;标称性;没有自然次序的名义型或分类型应答 存在;存在与否;特征标识;身份;身份标识 微生物学;微生物学试验;微生物学试验（培养、DNA、抗原及抗体） 时刻;随机;随意;瞬间 皮疽组织胞浆菌 Ab 皮疽组织胞浆菌;美洲型组织胞浆菌;鼻疽性组织浆菌 皮疽组织胞浆菌抗体 组织胞浆菌属 组织胞浆菌病 美洲型组织胞浆菌 Ab 美洲型组织胞浆菌抗体 荚膜组织胞浆菌 Ab 血清或血浆 鼻疽性组织浆菌 Ab 鼻疽性组织浆菌抗体

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=90232-0