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Part Description

LP15629-6   Heparan sulfate
Heparan sulfate is a derived disaccharide that accumulates in lysosomes, extracellular matrix, and body fluids of people with mucopolysaccharidoses (MPSs). MPSs are rare disorders caused by a deficiency of enzymes that break down glycosaminoglycans (GAGs). Symptoms of MPS vary due to which storage product accumulates and the level of enzymatic function or concentration that remains. Symptoms include musculoskeletal, airway, cardiac, and central nervous system disorders. Treatments include hematopoietic stem cell transplantation for the more critical forms of MPS and intravenous enzyme replacement therapy for the others. Treatment is most effective when it is initiated before irreversible tissue damage has occurred. Because MPS is so rare and the symptoms so variable, it is difficult to diagnose in its earliest stages. A solution to that problem is the development of newborn screening assays that can detect heparan sulfate, though the levels in the dried blood spot samples do not appear to predict the severity of disease. The pattern of dermatan and heparan sulfate can help distinguish between the different MPSs. PMID: 23084433 Source: Regenstrief LOINC

LOINC Names Get Info

Fully-Specified Name
Heparan sulfate:SCnc:Pt:Bld.dot:Qn:
Long Common Name
Heparan sulfate [Moles/volume] in DBS
Short Name
Heparan sulfate DBS-sCnc
Display Name
Heparan sulfate (DBS) [Moles/Vol]
Consumer Name Alpha Get Info
Heparan sulfate, Dried blood spot

Part Model Get Info

  • Component
    Heparan sulfate
    LP15629-6
    • Analyte
      Heparan sulfate
      LP15629-6
      • Component Numerator
        Heparan sulfate
        LP15629-6
        • Component Numerator Core
          Heparan sulfate
          LP15629-6
        • Component Numerator Core Suffix
          NULL
           
      • Component Denominator
        NULL
         
        • Component Denominator Core
          NULL
           
        • Component Denominator Core Suffix
          NULL
           
    • Challenge
      NULL
       
    • Adjustment
      NULL
       
    • Count
      NULL
       
  • Property
    SCnc
    LP6860-3
  • Time
    Pt
    LP6960-1
  • System
    Bld.dot
    LP21304-8
    • System Core
      Bld.dot
      LP21304-8
    • Super System
      NULL
       
  • Scale
    Qn
    LP7753-9
  • Method
    NULL
     

Basic Attributes

Class
CHEM
Type
Laboratory
First Released
Version 2.65
Last Updated
Version 2.65 (ADD)
Order vs. Observation
Both

Member of these Panels

LOINCLong Common Name
94586-5Dermatan sulfate and heparan sulfate and keratan sulfate panel - DBS

Language Variants Get Info

TagLanguageTranslation
cs-CZCzech (Czechia)Heparansulfát:Látková koncentrace:Časový bod:Suchá krevní kapka (DBS):Kvantitativní:
el-GRGreek (Greece)Θειική ηπαράνη:SCnc:Pt:Bld.dot:Qn:
Synonyms: Bld.dot CHEM Pt Qn SCnc Αίμα Θειικά άλατα Θειική ηπαράνη
es-ESSpanish (Spain)Heparán sulfato:Concentración de sustancia:Punto temporal:gota de sangre (papel de filtro):Qn:
Synonyms: Cuantitativo
es-MXSpanish (Mexico)Sulfato de Heparán:Concentración de sustancias:Punto temporal:DBS:Cuantitativo:
et-EEEstonian (Estonia)Heparaansulfaat:SCnc:Pt:Vereplekk:Qn:
Synonyms: Aine kontsentratsioon Juhuslik Kvantitatiivne Veri
fr-FRFrench (France)Héparane sulfate:Moles/Volume:Ponctuel:Sang buvard:Numérique:
fr-CAFrench (Canada)Héparane sulfate:Concentration de substance:Temps ponctuel:Sang sur papier filtre:Quantitatif:
fr-BEFrench (Belgium)Héparane-sulfate:Concentration de substance:Temps ponctuel:Sang sur papier filtre:Quantitatif:
Synonyms: SO4
it-ITItalian (Italy)Eparan solfato:SCnc:Pt:Sangue.su carta da filtro:Qn:
Synonyms: Chimica Concentrazione di Sostanza Punto nel tempo (episodio) Sangue Spot sangue secco
nl-NLDutch (Netherlands)heparansulfaat:mol/volume:moment:gedroogde bloedspot:kwantitatief:
ru-RURussian (Russian Federation)Гепаран сульфат:МолКонц:ТчкВрм:Кр.Сух.капл:Колич:
Synonyms: Гепарансульфат Количественный Кровь Кровь сухая капля Молярность;Молярная объёмная концентрация Точка во времени;Момент
tr-TRTurkish (Turkey)Heparan sülfat:SubKons:Zmlı:Kan.nokta:Kant:
zh-CNChinese (China)硫酸类肝素:物质的量浓度:时间点:全血.斑点:定量型:
Synonyms: SO4;SO4-2;Sulf;硫酸;硫酸根;硫酸盐;硫酸酯 克分子浓度;克分子浓度(单位体积);摩尔浓度;摩尔浓度(单位体积);物质的量浓度(单位体积) 全血斑点(滤纸);滤纸;血液.斑点;血液斑点(滤纸) 化学;化学检验项目;化学检验项目类;化学类;化学试验;非刺激耐受型化学检验项目;非刺激耐受型化学检验项目类;非刺激耐受型化学试验;非刺激耐受型化学试验类 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 时刻;随机;随意;瞬间 硫酸乙酰型肝素;硫酸乙酰肝素;硫酸肝素 血;血液

Example Units

UnitSource
nmol/LExample UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=90235-3