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Part Description

LP268095-9   Eculizumab
Eculizumab is monoclonal antibody that binds to the C5 complement component and is used to treat atypical hemolytic uremic syndrome (aHUS). aHUS is characterized by hemolytic anemia that leads to the presence of schistocytes, thrombocytopenia, renal damage, and other organ system impairment. aHUS is caused by a rare genetic mutation that interferes with the regulation of the complement system and leads to thrombotic microangiopathy (TMA). Prior to the development of eculizumab, the only treatment for aHUS was plasmapheresis, which did not stop progressive organ impairment. Eculizumab is an extremely expensive but effective therapy against aHUS and provides good outcomes and improved quality of life for patients with aHUS. Eculizumab has also been found to increase the possibility for the repair of renal damage. PMID: 27766045Measurement of eculizumab in serum is used for monitoring and therapy optimization. Source: Regenstrief LOINC

LOINC Names Get Info

Fully-Specified Name
Eculizumab:MCnc:Pt:Ser:Qn:
Long Common Name
Eculizumab [Mass/volume] in Serum
Short Name
Eculizumab Ser-mCnc
Display Name
Eculizumab (S) [Mass/Vol]
Consumer Name Alpha Get Info
Eculizumab, Blood

Part Model Get Info

  • Component
    Eculizumab
    LP268095-9
    • Analyte
      Eculizumab
      LP268095-9
      • Component Numerator
        Eculizumab
        LP268095-9
        • Component Numerator Core
          Eculizumab
          LP268095-9
        • Component Numerator Core Suffix
          NULL
           
      • Component Denominator
        NULL
         
        • Component Denominator Core
          NULL
           
        • Component Denominator Core Suffix
          NULL
           
    • Challenge
      NULL
       
    • Adjustment
      NULL
       
    • Count
      NULL
       
  • Property
    MCnc
    LP6827-2
  • Time
    Pt
    LP6960-1
  • System
    Ser
    LP7567-3
    • System Core
      Ser
      LP7567-3
    • Super System
      NULL
       
  • Scale
    Qn
    LP7753-9
  • Method
    NULL
     

Basic Attributes

Class
DRUG/TOX
Type
Laboratory
First Released
Version 2.65
Last Updated
Version 2.65 (ADD)
Order vs. Observation
Both

Member of these Panels

LOINCLong Common Name
101922-3Eculizumab Monitoring Panel

Language Variants Get Info

TagLanguageTranslation
cs-CZCzech (Czechia)Ekulizumab:Hmotnostní koncentrace:Časový bod:Sérum:Kvantitativní:
el-GRGreek (Greece)Εκουλιζουμάμπη:MCnc:Pt:Ορός:Qn:
Synonyms: DRUG/TOX MCnc Pt Qn Εκουλιζουμάμπη Ορός
es-ESSpanish (Spain)Eculizumab:Concentración de masa:Punto temporal:Suero:Qn:
Synonyms: Cuantitativo
es-MXSpanish (Mexico)Eculizumab:Concentración de masa:Punto temporal:Suero:Cuantitativo:
fr-FRFrench (France)Éculizumab:Masse/Volume:Ponctuel:Sérum:Numérique:
it-ITItalian (Italy)Eculizumab:MCnc:Pt:Siero:Qn:
Synonyms: Concentrazione di Massa Livelli farmacologici e tossicologia Punto nel tempo (episodio) Siero
zh-CNChinese (China)依库珠单抗:质量浓度:时间点:血清:定量型:
Synonyms: 依库组单抗;艾库组单抗;依库丽单抗 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 时刻;随机;随意;瞬间 毒品 毒品类 水平;浓度;质量浓度(单位体积) 药品类 药物 药物/毒理学;药物/毒理学试验;药物毒理学试验;药物毒理学试验类 药物类

Example Units

UnitSource
ug/mLExample UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=90240-3