Version 2.80

Part Description

LP268510-7   Cells.CD24-FLAER-
Paroxsmal nocturnal hemoglobinuria (PNH) is a condition that causes hemolytic anemia, bone marrow failure, and a proclivity to develop thrombosis. PNH occurs when the PIG-A gene of bone marrow stem cells undergoes mutation. Stems cells develop into erythrocytes (RBCs), white blood cells (WBCs), platelets, and mature cells that contain the PIG-A gene mutation, and as a result, lack a sufficient number of glycosylphosphatidylinositol-anchored protein (GPI-AP). The GPI-APs have various roles, some of which are to help to prevent RBC destruction, fight infection, and promote thrombosis.[https://www.hopkinsmedicine.org/kimmel_cancer_center/types_cancer/paroxysmal_nocturnal_hemoglobinuria_PNH.html] CD14, 16, 24, and 59 are GPI-linked proteins that are used as markers for the presence of GPI, as is fluorescent aerolysin (FLAER), which binds to GPI-APs. Patients with PNH lack sufficient GPIs and therefore have reduced expression of these cell markers and FLAER compared to patients without PNH. Patients with complete loss of CD59 are more likely to have hemolysis compared to patients with partial loss of CD59. Source: Regenstrief LOINC

Fully-Specified Name

Component
Cells.CD24-FLAER-/Cells.CD15
Property
NFr
Time
Pt
System
Bld
Scale
Qn
Method

Additional Names

Long Common Name
CD24-FLAER- cells/Cells.CD15 (Neutrophils) in Blood
Short Name
CD24-FLAER- cells/CD15 NFr Bld
Display Name
CD24-FLAER- cells/Cells.CD15 (Bld)
Consumer Name Alpha Get Info
CD24-FLAER- cells/Cells.CD15, Blood

Basic Attributes

Class
CELLMARK
Type
Laboratory
First Released
Version 2.65
Last Updated
Version 2.79 (NAM)
Change Reason
Release 2.79: COMPONENT: Triggered by Coll w SCT: This is a specific fraction case where the denominator is percentage or /100. Because the logic is that the percentage piece is captured by Property: NFr (Numeric Fraction), and by Unit: %, therefore, it is redundant to include "100" in the component; Release 2.72: LONG_COMMON_NAME: Added the cell type name to the display name to align with reference lab convention.;
Order vs. Observation
Both

Member of these Panels

LOINC Long Common Name
90735-2 PNH GPI-Linked WBC and RBC Ag Panel - Blood

Language Variants Get Info

Tag Language Translation
el-GR Greek (Greece) Κύτταρα.CD24-FLAER-/Κύτταρα.CD15:NFr:Pt:Αίμα:Qn:
Synonyms: CD15 CD24 NFr Κύτταρα Κύτταρα.CD15 Κύτταρα.CD24 Κύτταρα.CD24-FLAER-
es-ES Spanish (Spain) Células CD24-FLAER-/Porcentaje CD15:Fracción numérica:Punto temporal:Sangre:Qn:
Synonyms: Cuantitativo
es-MX Spanish (Mexico) Celdas.CD24-FLAER- / 100 células.CD15:Fracción numérica:Punto temporal:Sangre:Cuantitativo:
fr-FR French (France) CD24-FLAER-/100 cellules CD15:Fraction de nombres:Ponctuel:Sang:Numérique:
it-IT Italian (Italy) Cellule.CD24-FLAER-/Cellule.CD15:NFr:Pt:Sangue:Qn:
Synonyms: Cellule CD15 Cellule CD24 Cellule CD24-FLAER- Frazione numerica Modelli di superficie cellulare Punto nel tempo (episodio) Sangue
zh-CN Chinese (China) 细胞.CD24-FLAER-/细胞.CD15:计数型分数:时间点:全血:定量型:
Synonyms: 3-FAL;3-FL;Lacto-n-neo-fucopentaose III;LeuM1;Leu-M1;Lewis X;Lex;LNFP III;M-1;My1;My-1;SSEA-1;X-hapten;X-半抗原;乳糖-n-neo-岩藻戊糖 III Alexa Fluor 488-标记的气单胞菌溶素突变体 Alexa Fluor 488-标记的气溶毒素突变体 Alexa Fluor 488-标记的气溶素突变体 Alexa Fluor 488-标记的突变体气单胞菌溶素 Alexa Fluor 488-标记的突变体气溶毒素 Alexa Fluor 488-标记的突变体气溶素 Alexa Fluor 488-标记的突变型气单胞菌溶素 Alexa Fluor 488-标记的突变型气溶毒素 Alexa Fluor 488-标记的突变型气溶素 BA-1;HSA;发现于 B-细胞之上。与大多数 B-细胞急性淋巴细胞白血病、大多数的成熟 B-细胞肿瘤以及急性单核细胞性白血病（Acute monocytoid leukemias）相关。;热稳定性抗原;热稳定抗原;热稳定抗原（heat stable antigen，HSA）;耐热抗原 CD15细胞 CD24细胞 Fluor 488-标记的气单胞菌溶素突变体 Fluor 488-标记的气溶毒素突变体 Fluor 488-标记的气溶素突变体 Fluor 488-标记的突变体气单胞菌溶素 Fluor 488-标记的突变体气溶毒素 Fluor 488-标记的突变体气溶素 Fluor 488-标记的突变型气单胞菌溶素 Fluor 488-标记的突变型气溶毒素 Fluor 488-标记的突变型气溶素 Fluor 488-标记的突变型气溶素（Fluor 488-labeled mutant aerolysin，FLAER） 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 数量型分数;数量或计数型分数;数量型分数或计数型分数 时刻;随机;随意;瞬间 细胞含量;细胞性;细胞性质;细胞构成;细胞类 细胞标志物 血;血液

Example Units

Unit Source
% Example UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=90737-8