90835-0
Myelin associated glycoprotein IgM Ab [Presence] in Cerebral spinal fluid by Immunoblot
Active
Part Description
LP18213-6 Myelin associated glycoprotein
Myelin associated glycoprotein (MAG) is a 100 kDa transmembrane glycoprotein found in the periaxonal membranes of Schwann cells and oligodendrocytes of myelin sheaths. Despite the fact that MAG is a known white matter inhibitor of axonal regeneration and as a receptor for IgM antibodies that demyelinates peripheral nerves, it has important roles that promote normal formation and maintenance of myelinated axons. There are two apparent functions of MAG which are to act as a ligand for an axonal receptor which maintains myelinated axons, and to act as an axonal signal receptor that promotes differentiation, maintenance, and survival of oligodendrocytes. MAG shares an epitope with other glyoconjugates that is the target protein in autoimmune peripheral neuropathy, that is associated with IgM gammopathy which causes the death of oligodendrocytes that is seen in multiple sclerosis. PMID: 17241126
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- Myelin associated glycoprotein Ab.IgM
- Property
- PrThr
- Time
- Pt
- System
- CSF
- Scale
- Ord
- Method
- IB
Additional Names
- Short Name
- MAG IgM CSF Ql IB
- Display Name
- Myelin associated glycoprotein IgM IB Ql (CSF)
- Consumer Name Alpha Get Info
- Myelin associated glycoprotein IgM antibody, Spinal fluid
Example Answer List: LL2038-9
Source: Quest Diagnostics Inc.Answer | Code | Score | Answer ID |
---|---|---|---|
PositiveCopyright http://snomed.info/sct ID:10828004 Positive (qualifier value) | LA6576-8 | ||
NegativeCopyright http://snomed.info/sct ID:260385009 Negative (qualifier value) | LA6577-6 | ||
IndeterminateCopyright http://snomed.info/sct ID:82334004 Indeterminate (qualifier value) | LA11884-6 |
Basic Attributes
- Class
- SERO
- Type
- Laboratory
- First Released
- Version 2.65
- Last Updated
- Version 2.65
- Order vs. Observation
- Both
Language Variants Get Info
Tag | Language | Translation |
---|---|---|
es-ES | Spanish (Spain) | Glicoproteína asociada a la mielina IgM: |
es-MX | Spanish (Mexico) | Glicoproteína Ab.IgM asociada a mielina: |
fr-BE | French (Belgium) | Glycoprotéine associée à la myéline Anticorps. IgM: Synonyms: Anticorps |
fr-CA | French (Canada) | Glycoprotéine associée à la myéline, IgM: |
fr-FR | French (France) | MAG anticorps IgM: |
it-IT | Italian (Italy) | Mielina, glicoproteina associata Ab.IgM: Synonyms: Anticorpi IgM anticorpo Glicoproteina associata alla mielina Immunoblot (IB) Liquido cerebrospinale Presenza o Soglia Punto nel tempo (episodio) Sierologia (anticorpi e la maggior parte degli ant |
nl-NL | Dutch (Netherlands) | myeline-geassocieerd glycoproteïne As.IgM: Synonyms: antistof; |
ru-RU | Russian (Russian Federation) | Миелин ассоциированный гликопротеин Ат.IgM: Synonyms: Антитело Иммуноблот (ИБ) Миелин-ассоциированный гликопротеин Порядковый Точка во времени; |
tr-TR | Turkish (Turkey) | Miyelinle ilişkili glikoprotein Ab.IgM: Synonyms: Ak Ak.IgM Mevcut |
zh-CN | Chinese (China) | 髓磷脂相关糖蛋白 抗体.IgM: Synonyms: Ab.IgM; |
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