Myelin associated glycoprotein IgM Ab [Presence] in Cerebral spinal fluid by Immunoblot
LP18213-6 Myelin associated glycoprotein
Myelin associated glycoprotein (MAG) is a 100 kDa transmembrane glycoprotein found in the periaxonal membranes of Schwann cells and oligodendrocytes of myelin sheaths. Despite the fact that MAG is a known white matter inhibitor of axonal regeneration and as a receptor for IgM antibodies that demyelinates peripheral nerves, it has important roles that promote normal formation and maintenance of myelinated axons. There are two apparent functions of MAG which are to act as a ligand for an axonal receptor which maintains myelinated axons, and to act as an axonal signal receptor that promotes differentiation, maintenance, and survival of oligodendrocytes. MAG shares an epitope with other glyoconjugates that is the target protein in autoimmune peripheral neuropathy, that is associated with IgM gammopathy which causes the death of oligodendrocytes that is seen in multiple sclerosis.[PMID: 17241126] Source: Regenstrief LOINC
- Myelin associated glycoprotein Ab.IgM
- Short Name
- MAG IgM CSF Ql IB
- Display Name
- Myelin associated glycoprotein IgM IB Ql (CSF)
- Consumer Name Alpha
- Myelin associated glycoprotein IgM antibody, Spinal fluid
Example Answer List: LL2038-9Source: Quest Diagnostics Inc.
|PositiveCopyright http://snomed.info/sct ID:10828004 Positive (qualifier value)||LA6576-8|
|NegativeCopyright http://snomed.info/sct ID:260385009 Negative (qualifier value)||LA6577-6|
|IndeterminateCopyright http://snomed.info/sct ID:82334004 Indeterminate (qualifier value)||LA11884-6|
- First Released
- Version 2.65
- Last Updated
- Version 2.65
- Order vs. Observation
|es-ES||Spanish (Spain)||Glicoproteína asociada a la mielina IgM:
|tr-TR||Turkish (Turkey)||Miyelinle ilişkili glikoprotein Ab.IgM:
|fr-BE||French (Belgium)||Glycoprotéine associée à la myéline Anticorps. IgM:
|it-IT||Italian (Italy)||Mielina, glicoproteina associata Ab.IgM:
|nl-NL||Dutch (Netherlands)||myeline-geassocieerd glycoproteïne As.IgM:
|fr-CA||French (Canada)||Glycoprotéine associée à la myéline , IgM:
|zh-CN||Chinese (China)||髓磷脂相关糖蛋白 抗体.IgM:
|fr-FR||French (France)||MAG anticorps IgM:
|ru-RU||Russian (Russian Federation)||Миелин ассоциированный гликопротеин Ат.IgM:
|es-MX||Spanish (Mexico)||Glicoproteína Ab.IgM asociada a mielina:
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