Version 2.77

Part Description

LP31707-0   Neuronal nuclear type 3
Neuronal nuclear type 3 Ab (ANNA-3) is one of three neuronal nuclear paraneoplastic antibodies that primarily binds to the nuclei of cerebellar Purkinje neurons and to renal glomerular podocytes. Symptoms of the presence of ANNA-3 include sensory or sensorimotor neuropathies, cerebellar ataxia, myelopathy, brain stem and limbic encephalopathy.It's presence in serum is most commonly indicative of a small-cell malignant tumor, most of which are primary tumors of the lung.Fluorescent staining patterns are used to distinguish ANNA-3 from the other two neuronal nuclear types, ANNA-1 and ANNA-2. ANNA-3 binds the nuclei of Purkinje neurons in the cerebellar cortex more than the molecular neurons, and does not bind granular neurons. ANNA-3 binds only the nuclei of indentate neurons, while ANNA-1 and ANNA-2 bind both the nuclei and cytoplasm of all neurons. ANNA-3 binds the nuclei of glomuerular podocytes in of the renal cortex in 10 of 11 sera. For the same cell type, ANNA-2 binds both the nuclei and cytoplasm in 8 of 32 sera, and ANNA-1 does not bind the podocytes at all. PMID: 11558786 Source: Regenstrief LOINC

Fully-Specified Name

Component
Neuronal nuclear type 3 Ab
Property
PrThr
Time
Pt
System
CSF
Scale
Ord
Method
IF

Additional Names

Short Name
Hu3 Ab CSF Ql IF
Display Name
Neuronal nuclear type 3 Ab IF Ql (CSF)
Consumer Name Alpha Get Info
Neuronal nuclear type 3 antibody, Spinal fluid

Example Answer List: LL2038-9

Source: Quest Diagnostics Inc.
Answer Code Score Answer ID
PositiveCopyright http://snomed.info/sct ID:10828004 Positive (qualifier value) LA6576-8
NegativeCopyright http://snomed.info/sct ID:260385009 Negative (qualifier value) LA6577-6
IndeterminateCopyright http://snomed.info/sct ID:82334004 Indeterminate (qualifier value) LA11884-6

Basic Attributes

Class
SERO
Type
Laboratory
First Released
Version 2.65
Last Updated
Version 2.65
Order vs. Observation
Both

Member of these Panels

LOINC Long Common Name
94818-2 Paraneoplastic Ab panel - Cerebral spinal fluid by Immunofluorescence

Language Variants Get Info

Tag Language Translation
es-ES Spanish (Spain) Neuronal nuclear tipo 3 Anticuerpos:PrThr:Punto temporal:Líquido Cefalorraquideo:Ord:Inmunofluorescencia (IF)
es-MX Spanish (Mexico) Tipo nuclear neuronal 3 Ab:Presencia o umbral:Punto temporal:Fluído espinal cerebral:Ordinal:Inmunofluorescencia (IF)
fr-FR French (France) Hu3 anticorps:Présence/Seuil:Ponctuel:Liquide céphalorachidien:Qualitatif:Immunofluorescence
fr-BE French (Belgium) Type 3 neuronal nucléaire Ac:PrThr:Temps ponctuel:LCR:Ordinal:Immunofluorescence
Synonyms: Anticorps
fr-CA French (Canada) Neuronal nucléaire de type 3 , Ac:Présence-Seuil:Temps ponctuel:LCR:Ordinal:Immunofluorescence
it-IT Italian (Italy) Nucleare neuronale tipo 3 Ab:PrThr:Pt:LCS:Ord:IF
Synonyms: anticorpo Immunofluorescenza (IF) Liquido cerebrospinale Presenza o Soglia Punto nel tempo (episodio) Sierologia (anticorpi e la maggior parte degli ant
nl-NL Dutch (Netherlands) neuronaal nucleair type 3 As:aanwezigheid:moment:liquor cerebrospinalis:ordinaal:immunofluorescentie
Synonyms: antistof; antilichaam IF soort
pl-PL Polish (Poland) Typ 3 neuronalny jądrowy Ab:granica wykrywalności:punkt w czasie:płyn mózgowo-rdzeniowy:półilościowy:immunofluorescencja
Synonyms: Przeciwciała do antygenów jądrowych neuronów typu 3 Przeciwciała onkoneuronalne
ru-RU Russian (Russian Federation) Нейрональный ядерный тип 3 Ат:PrThr:ТчкВрм:ЦСЖ:Пор:ИФ
Synonyms: Антинейрональный Антитело Иммунофлюоресценция (ИФ) Порядковый Точка во времени;Момент Цереброспинальная жидкость
tr-TR Turkish (Turkey) Nöronal nükleer tip 3 Ab:MevcEşik:Zmlı:BOS:Srl:IF
Synonyms: Ak Çekirdek İmmünflorerans Mevcut
zh-CN Chinese (China) 神经元细胞核 3 型 抗体:存在情况或阈值:时间点:脑脊液:序数型:免疫荧光法
Synonyms: Ⅲ Ab;自身抗体 ANNA 3 Ab ANNA 3 抗体 ANNA 3;ANNA-3;Hu3;神经元核 3 型;神经元细胞核 3 型（Neuronal nuclear type 3，ANNA 3） ANNA-3 Ab ANNA-3 抗体 CSF CSF;脊髓液;Cerebral spinal fluid;脑脊髓液 FANA Hu3 Ab Hu3 抗体 IFA法;IF法;抗补体免疫荧光法;时间分辨荧光法;荧光原位杂交技术;荧光原位杂交法;荧光抗体 III 三 依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型 叁 型 存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值） 时刻;随机;随意;瞬间 核;胞核 核心抗原抗体免疫荧光 神经元性;神经元的 神经元核 神经元核 3 型 Ab 神经元核 3 型抗体 神经元细胞核 3 型 Ab 脊液 脊髓液 脑脊液（Cerebral spinal fluid，CSF） 脑脊髓液 血清;血清学;血清学检验项目;血清学检验项目 (非微生物学);血清学检验项目（非微生物学）;血清学检验项目类;血清学检验项目类 (非微生物学);血清学类;血清学类检验项目;血清学类检验项目 (非微生物学);血清学类试验;血清学类试验 (非微生物学);血清学试验;血清学试验 (非微生物学);血清学试验（非微生物学）;血清学试验类 (非微生物学);血清类

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=90836-8