90919-2

Coagulation factor VIII.recombinant.bound/von Willebrand factor (vWf) Ag in Plasma by Immunoassay

Active

Term Description

This test measures the binding activity of von Willebrand factor (vWF) to Factor VIII as the ratio of the amount of exogenous recombinant Factor VIII bound to vWF in the patient sample to the amount of vWF in the patient sample. It is used to differentiate between various bleeding disorders including hemophilia A and type 2N von Willebrand disease (2N vWD, VWD2N, or Type 2 Normandy). Type 2N vWD is caused by mutations to the Factor VIII binding site of vWF, which results in reduced binding and faster clearance of Factor VIII. Patients with type 2N vWD usually have reduced Factor VIII activity with normal VWF levels. PMID: 19298374

Part Description

LP14587-7 Factor VIII
Blood-coagulation factor VIII; Antihemophilic factor that is part of the factor VIII/von Willebrand factor complex. Factor VIII is produced in the liver and acts in the intrinsic pathway of blood coagulation. It serves as a cofactor in factor X activation and this action is markedly enhanced by small amounts of thrombin. Source: National Library of Medicine, MeSH 2006

LOINC Names Get Info

Fully-Specified Name: Coagulation factor VIII.recombinant.bound/von Willebrand factor Ag:RelRto:Pt:Plas:Qn:IA
Long Common Name: Coagulation factor VIII.recombinant.bound/von Willebrand factor (vWf) Ag in Plasma by Immunoassay
Short Name: Fact VIII.recomb.bound/vWF Ag Plas IA
Display Name: Bound rFVIII/vWf Ag IA (P) [Relative ratio]
Consumer Name Alpha Get Info: Bound Recombinant Factor VIII/vWF Antigen, Blood

Part Model Get Info

Component
Coagulation factor VIII.recombinant.bound/von Willebrand factor Ag
LP285782-1
- Analyte
  Coagulation factor VIII.recombinant.bound/von Willebrand factor Ag
  LP285782-1
  - Component Numerator
    Coagulation factor VIII.recombinant.bound
    LP269616-1
    - Component Numerator Core
      Coagulation factor VIII.recombinant.bound
      LP269616-1
    - Component Numerator Core Suffix
      NULL
  - Component Denominator
    von Willebrand factor Ag
    LP70347-7
    - Component Denominator Core
      von Willebrand factor
      LP175752-7
    - Component Denominator Core Suffix
      Ag
      LP20666-1
- Challenge
  NULL
- Adjustment
  NULL
- Count
  NULL
Property
RelRto
LP6854-6
Time
Pt
LP6960-1
- Time Core
  Pt
  LP6960-1
- Time Modifier
  NULL
System
Plas
LP7479-1
- System Core
  Plas
  LP7479-1
- Super System
  NULL
Scale
Qn
LP7753-9
Method
IA
LP217197-5

Basic Attributes

Class: COAG
Type: Laboratory
First Released: Version 2.65
Last Updated: Version 2.68 (MIN)
Change Reason: Release 2.68: LONG_COMMON_NAME: Removed extra "Ag"
Order vs. Observation: Both

Language Variants Get Info

Tag	Language	Translation
cs-CZ	Czech (Czechia)	Koagulační faktor VIII.rekombinantní.vázaný/von Willebrandův faktor Ag:Relativní poměr:Časový bod:Plazma:Kvantitativní:Imunoanalýza
el-GR	Greek (Greece)	Παράγοντας πήξης VIII.ανασυνδυασμένος.δεσμευμένος/παράγοντας Von Willebrand Αντιγόνο:RelRto:Pt:Πλάσμα:Qn:IA Synonyms: COAG IA Pt Qn RelRto Παράγοντας VIII παράγοντας Von Willebrand Παράγοντας πήξης VIII Παράγοντας πήξης VIII.ανασυνδυασμένος.δεσμευμένος Πήξη Πλάσμα
es-ES	Spanish (Spain)	Factor VIII de coagulación recombinante unido/factos von Willebrand Antígeno:Ratio relativo:Punto temporal:Plasma:Qn:IA Synonyms: Cuantitativo vWF:Ag
es-MX	Spanish (Mexico)	Factor de coagulación VIII, recombinante, unido / factor Ag de von Willebrand:Razón relativa:Punto temporal:Plasma:Cuantitativo:Inmunoensayo
fr-FR	French (France)	Factor VIII recombinant lié/facteur Willebrand Ag:Ratio relatif:Ponctuel:Plasma:Numérique:Immunoanalyse
it-IT	Italian (Italy)	Fattore di coagulazione VIII.ricombinante.legato/fattore di von Willebrand, Ag:RelRto:Pt:Plasma:Qn:IA Synonyms: Ag fattore di von Willebrand Fattore di von Willebrand (vWf) Immunoassay Plasma Punto nel tempo (episodio) Rapporto Relativo Studio di coagulazione
nl-NL	Dutch (Netherlands)	stollingsfactor VIII.recombinant.gebonden/von Willebrand-factor Ag:relatieve verhouding:moment:plasma:kwantitatief:immunoassay Synonyms: coagulatiemethode IA
pl-PL	Polish (Poland)	Rekombinowany czynnik krzepnięcia VIII, związany/czynnik von Willebranda Ag:współczynnik względny:punkt w czasie:osocze:ilościowy:metoda immunologiczna Synonyms: Antygen czynnika von Willebranda (vWf) Czynnik von Willebranda (vWf) Stosunek rekombinowanego czynnika VIII krzepnięcia do antygenu czynnika von Willebranda
zh-CN	Chinese (China)	凝血因子 VIII.重组.结合型/von Willebrand 因子抗原:相对比率:时间点:血浆:定量型:免疫测定法 Synonyms: AHF;AHG;VIII:C;凝血因子 VIII 凝血活性;凝血因子Ⅷ;凝血因子Ⅷ凝血活性;循环型抗凝物;循环型抗凝物质;抗血友病因子;抗血友病因子（Antihemophilic factor，AHF）;抗血友病球蛋白;抗血友病球蛋白（Antihemophilic globulin，AHG）;血小板辅因子 A FVIII von Willebrand 因子 Ag von Willebrand von Willebrand 因子（von Willebrand Factor，vWf）;vWf;vWf 因子;血管性假血友病因子;血管性血友病因子 vWf 因子 Ag vWf 因子抗原免疫测定;免疫分析法;免疫检定法;免疫检定;免疫试验;酶免疫测定法;酶免疫测定;酶免疫分析法;酶免疫检定法;酶免疫检定;酶免疫试验冯·威勒布兰德冯威勒布兰德冯威勒布兰德氏凝固;凝固现象;凝血;凝血作用;凝血功能;凝血功能类;凝血类成分;凝血过程凝血功能;凝血功能试验;凝血过程;血液凝固;血液凝固功能;血液凝固过程凝血因子 VIII（凝血因子Ⅷ、因子 VIII、因子Ⅷ）.重组.结合型凝血因子Ⅷ;因子 VIII;因子Ⅷ;血液制品 - 凝血因子 VIII;血液制品 - 凝血因子Ⅷ;血液制品 - 因子 VIII;血液制品 - 因子Ⅷ 可用数量表示的;定量性;数值型;数量型;连续数值型标尺因子 8 因子 VIII 因素时刻;随机;随意;瞬间来自于不同体系的两种分析物之比;相对比;相对比值系数血管性血友病因子 Ag 血管性血友病因子抗原

Example Units

Unit	Source
{ratio}	Example UCUM Units

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Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.