Version 2.80

Part Descriptions

LP269809-2   MET gene amplification
MET gene amplification studies evaluate the number of copies of the MET gene present in a single cell. Amplification is determined based on the MET gene copy number and MET to centromere ratio. Different criteria have been proposed for what constitutes amplification, including a MET to centromere ratio of >= 2, an average MET gene copy number >=5, and at least 15 gene copies in 10% of the tumor cell nuclei that were counted. MET amplification is associated with worse prognosis in a variety of cancers, including non-small cell lung and gastroesophageal cancer. PMID: 27926778 Source: Regenstrief LOINC

LP62864-1   FISH
FISH (fluorescence in situ hybridization) is a cytogenetic technique used to detect and localize the presence or absence of specific DNA sequences on chromosomes. FISH uses fluorescent probes that bind to only those parts of the chromosome with which they show a high degree of sequence similarity. Fluorescence microscopy can be used to find out where the fluorescent probe bound to the chromosomes. FISH is often used for finding specific features in DNA for use in genetic counseling, medicine, and species identification. FISH can also be used to detect and localize specific mRNAs within tissue samples. In this context, it can help define the spatial-temporal patterns of gene expression within cells and tissues. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia , FISH

Fully-Specified Name

Component
MET gene amplification
Property
Find
Time
Pt
System
Bld/Tiss
Scale
Doc
Method
FISH

Additional Names

Long Common Name
MET gene amplification in Blood or Tissue by FISH
Short Name
MET amp Bld/T FISH
Display Name
MET amplification FISH Doc (Bld/Tiss)
Consumer Name Alpha Get Info
MET amplification, Blood or tissue specimen

Basic Attributes

Class
MOLPATH
Type
Laboratory
First Released
Version 2.65
Last Updated
Version 2.65 (ADD)
Order vs. Observation
Both

Language Variants Get Info

Tag Language Translation
el-GR Greek (Greece) Ενίσχυση του γονιδίου MET:Εύρεση:Pt:Αίμα/Ιστός:Doc:Φθορίζουσα υβριδοποίηση in situ
Synonyms: Γονίδιο Γονίδιο MET Ενίσχυση του γονιδίου MET Εύρεση
es-ES Spanish (Spain) Amplificación del gen MET:Hallazgo:Punto temporal:Sangre o tejido:Doc:Hibridación in situ fluoresente (FISH)
es-MX Spanish (Mexico) Amplificación del gen MET:Hallazgo:Punto temporal:Sangre o tejido:Documento:Hibridación fluorescente in situ (FISH)
fr-FR French (France) MET gène amplification:Recherche:Ponctuel:Sang/Tissu:Document:FISH
it-IT Italian (Italy) Gene MET, amplificazione:Osservazione:Pt:Sangue/Tess:Doc:FISH
Synonyms: Amplificazione gene MET Gene MET Ibridazione in situ fluorescente (FISH) Osservazione Patologia molecolare Punto nel tempo (episodio) Sangue Sangue o Tessuto Tessuto & Strisci
nl-NL Dutch (Netherlands) MET-genamplificatie:bevinding:moment:bloed of weefsel:document:FISH
zh-CN Chinese (China) MET 基因扩增:发现:时间点:全血/组织:文档型:FISH
Synonyms: Fluorescent in situ hybridization;荧光原位杂交 MET 原癌基因;受体酪氨酸激酶 Met;肝细胞生长因子受体;hepatocyte growth factor receptor;MET;MET proto-oncogene;receptor tyrosine kinase Met;AUTS9;HGFR;RCCP2;c-Met;DFNB97;OSFD 临床文档型;临床文档;文档;文书;医疗文书;临床医疗文书 全血或组织;血液/组织;血液或组织 分子病理学;分子病理学试验 发现是一个原子型临床观察指标，并不是作为印象的概括陈述。体格检查、病史、系统检查及其他此类观察指标的属性均为发现。它们的标尺对于编码型发现可能是名义型，而对于叙述型文本之中所报告的发现，则可能是叙述型。;发现物;所见;结果;结论 时刻;随机;随意;瞬间 未作说明的组织;组织;组织 & 涂片 血;血液 遗传基因;遗传因子;吉恩;生物基因

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=90926-7