91542-1
Myelin oligodendrocyte glycoprotein Ab [Titer] in Cerebral spinal fluid by Cell binding immunofluorescent assay
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Part Descriptions
LP231891-5 Myelin oligodendrocyte glycoprotein Ab
Myelin oligodendrocyte glycoprotein (MOG) is a protein made up of two polypeptides with molecular masses of 26 and 28 kilodaltons, respectively. MOG is located on the surface of myelin and oligodendrocyte cytoplasmic membranes and binds to the monoclonal antibody 8-18C5. PMID: 1373175 MOG is a probable autoantigen target associated with multiple sclerosis (MS) and other demyelinating diseases (DD) of the central nervous system. PMID: 1373175 That being said, there is variation in the level of MOG antibody found in patients with MS and DD with inconsistencies between MOG antibody measurements using western blot and ELISA test methods, making it a questionable biomarker for DD. PMID: 17294606 MOG IgG1 is the most prevalent isotype of IgG in patients with DD. PMID: 29063242
Source: Regenstrief LOINC
LP269367-1 CBA IFA
In cell binding assays or cell-based assays (CBA) also known as cell-based immunoassays, the DNA coding for a particular antigen is transfected into cultured cells, which are then used directly as substrate for antibody detection by immunofluorescence. The advantage of CBA IFA over conventional immunoassays is that purification and stability of the antigen is not required and they provide an in vivo substrate.
Source: Regenstrief LOINC,
Fully-Specified Name
- Component
- Myelin oligodendrocyte glycoprotein Ab
- Property
- Titr
- Time
- Pt
- System
- CSF
- Scale
- SemiQn
- Method
- CBA IFA
Additional Names
- Short Name
- MOG Ab Titr CSF CBA IFA
- Display Name
- Myelin oligodendrocyte glycoprotein Ab Cell binding immunofluorescent assay (CSF) [Titer]
- Consumer Name Alpha Get Info
- Myelin oligodendrocyte glycoprotein antibody, Spinal fluid
Basic Attributes
- Class
- SERO
- Type
- Laboratory
- First Released
- Version 2.66
- Last Updated
- Version 2.75
- Order vs. Observation
- Observation
Language Variants Get Info
Tag | Language | Translation |
---|---|---|
es-ES | Spanish (Spain) | Mielina de oligodendrocitos glicoproteína Anticuerpos: Synonyms: Semicuantitativo |
es-MX | Spanish (Mexico) | Glicoproteína de oligodendrocitos de mielina Ab: |
fr-FR | French (France) | MOG anticorps: |
it-IT | Italian (Italy) | Glicoproteina oligodendrocita mielinica Ab: Synonyms: anticorpo Fluorescenza indiretta degli anticorpi (IFA) Liquido cerebrospinale MOG Punto nel tempo (episodio) Sierologia (anticorpi e la maggior parte degli ant Titolo |
pl-PL | Polish (Poland) | Glikoproteina mieliny oligodendrocytów Ab: Synonyms: Glikoproteina mieliny oligodendrocytów Przeciwciała do glikoproteiny mieliny oligodendrocytów |
zh-CN | Chinese (China) | 髓鞘少突胶质细胞糖蛋白 抗体: Synonyms: Ab; |
Example Units
Unit | Source |
---|---|
{titer} | Example UCUM Units |
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