Version 2.78

Part Description

LP111251-7   T-cell receptor excision circle
T cell receptor excision circles (TRECs) are formed as a byproduct of T cell receptor (TCR) generation in the thymus. Every T cell has a unique TCR, and formation of TCRs involves DNA rearrangement into different combinations of variable, diversity, and joining sequences. As these combinations are created, the remaining fragments of excised DNA form circular structures, or TRECs. The number of TRECs is proportional to T cell production, with low TREC numbers being an indicator of inadequate T cell production. In newborns, dried blood spot TREC analysis is used to screen for severe combined immunodeficiency as well as other disorders associated with low T cell counts, such as DiGeorge syndrome, trisomy 21, CHARGE syndrome, and congenital leukemia. PMID: 25937517 Source: Regenstrief LOINC

Fully-Specified Name

Component
T-cell receptor excision circle
Property
Zscore
Time
Pt
System
Bld.dot
Scale
Qn
Method

Additional Names

Short Name
TREC Z-score DBS
Display Name
T-cell receptor excision circle (DBS) [Z-score]
Consumer Name Alpha Get Info
T-cell receptor excision circle, Dried blood spot

Basic Attributes

Class
CHEM
Type
Laboratory
First Released
Version 2.66
Last Updated
Version 2.66
Order vs. Observation
Both

Member of these Panels

LOINC Long Common Name
104191-2 Guanidinoacetate methyltransferase (GAMT) deficiency newborn screening panel
54089-8 Newborn screening panel American Health Information Community (AHIC)
62333-0 Severe combined immunodeficiency (SCID) newborn screening panel

Language Variants Get Info

Tag Language Translation
es-ES Spanish (Spain) Círculos de escisión del receptor de células T:Puntuación Z:Punto temporal:gota de sangre (papel de filtro):Qn:
Synonyms: Cuantitativo
es-MX Spanish (Mexico) Círculo de escisión del receptor de células T:Puntuación Z:Punto temporal:DBS:Cuantitativo:
fr-FR French (France) Récepteur cellules T cercle d'excision:Z score:Ponctuel:Sang buvard:Numérique:
it-IT Italian (Italy) Linfocita T, circolo di escissione recettore:Zscore:Pt:Sangue.su carta da filtro:Qn:
Synonyms: Chimica Circolo di escissione di recettore di linfocita T Linfocita T Punto nel tempo (episodio) Sangue Spot sangue secco Z-score
nl-NL Dutch (Netherlands) T-celreceptor excisiecirkel:Z-score:moment:gedroogde bloedspot:kwantitatief:
ru-RU Russian (Russian Federation) T-клеточного рецептора исключения круг:Z-тест:ТчкВрм:Кр.Сух.капл:Колич:
Synonyms: Z-тест Фишера Количественный Кровь Кровь сухая капля Точка во времени;Момент
tr-TR Turkish (Turkey) T-hücresi reseptörü excision circle:Zskoru:Zmlı:Kan.nokta:Kant:
zh-CN Chinese (China) T-细胞受体重排删除环:Z评分:时间点:全血.斑点:定量型:
Synonyms: T 细胞;UCHL-1 T-細胞受體重排刪除環;T-細胞受體切除環;T-细胞受体重排删除环;T-细胞受体重排切割环;T-cell receptor excision circle;TREC;T cell receptor rearrangement excision circle Z分;Z分值;Z分数;Z得分;Z-评分;Z评分（分值、得分、分数） 全血斑点(滤纸);滤纸;血液.斑点;血液斑点(滤纸) 化学;化学检验项目;化学检验项目类;化学类;化学试验;非刺激耐受型化学检验项目;非刺激耐受型化学检验项目类;非刺激耐受型化学试验;非刺激耐受型化学试验类 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 时刻;随机;随意;瞬间 血;血液

Example Units

Unit Source
{Zscore} Example UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=92007-4