92727-7
Tacrolimus [AUC] in Blood
Active
Term Description
Tacrolimus area under the curve (AUC) measurements are used to determine patient drug exposure and are used for therapeutic drug monitoring.
Part Descriptions
LP15182-6 Tacrolimus
Tacrolimus (also known as FK-506 or Prograf) is a macrolide isolated from the culture broth of a strain of Streptomyces tsukubaensis. It has strong immunosuppressive properties and is commonly used to prevent allograft rejection in transplant recipients. One of its modes of action is to prevent T-lymphocyte activation.
Source: National Library of Medicine, MeSH 2006
LP15182-6 Tacrolimus
Tacrolimus (also called FK-506 or fujimycin, Prograf, Advagraf, or Protopic) is amacrolide lactone, calcineurin inhibitor immunosuppresent used mainly after allogeneic organ transplant to lower the risk of organ rejection. It possesses strong immunosuppressive activity by preventing the activation by of T-lymphocytes in response to antigenic or mitogenic stimulation. Tacrolimus is also used in a topical preparation in the treatment of atopic dermatitis (eczema), severe refractory uveitis after bone marrow transplants, exacerbations of minimal change disease, TH2-mediated diseases such as Kimura's disease, and the skin condition vitiligo. There are potentially severe side effects from doses that are either too low or too high; inadequate tacrolimus concentrations may result in rejection of the transplanted organ, while high levels may lead to severe adverse effects includin nephrotoxicity, neurotoxicity, gastrointestinal disturbances, diabetogenesis, hypertension and malignant complications. [Wikipedia: Tacrolimus]
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Source: Wikipedia,
Tacrolimus
LOINC Names Get Info
- Fully-Specified Name
- Tacrolimus:
TmMCnc: Pt: Bld: Qn: - Long Common Name
- Tacrolimus [AUC] in Blood
- Short Name
- Tacrolimus Bld-AUC
- Display Name
- Tacrolimus (Bld) [AUC]
- Consumer Name Alpha Get Info
- Tacrolimus, Blood
Part Model Get Info
Basic Attributes
- Class
- DRUG/TOX
- Type
- Laboratory
- First Released
- Version 2.66
- Last Updated
- Version 2.66 (ADD)
- Order vs. Observation
- Both
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| cs-CZ | Czech (Czechia) | Takrolimus: |
| de-DE | German (Germany) | Tacrolimus: |
| el-GR | Greek (Greece) | Τακρόλιμους: Synonyms: DRUG/TOX Pt Qn TmMCnc Αίμα Τακρόλιμους |
| es-ES | Spanish (Spain) | Tacrolimus: Synonyms: Cuantitativo |
| es-MX | Spanish (Mexico) | Tacrolimus: |
| fr-CA | French (Canada) | Tacrolimus: |
| fr-FR | French (France) | Tacrolimus: |
| it-IT | Italian (Italy) | Tacrolimus: Synonyms: FK-506 Livelli farmacologici e tossicologia Punto nel tempo (episodio) Sangue |
| zh-CN | Chinese (China) | 他克莫司: Synonyms: 可用数量表示的; |
Example Units
| Unit | Source |
|---|---|
| ug.h/L | Example UCUM Units |
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