92748-3

Lyso-sphingomyelin [Moles/volume] in Blood

Active

Part Description

LP310425-6 Lyso-sphingomyelin
Lyso-sphingomyelin (LSM, sphingosylphosphorylcholine) is a biomarker for Niemann-Pick disease types A, B and C, genetically distinct metabolic disorders. Niemann-Pick types A/B and C share clinical features including hepatospenomegaly and specific neurological symptoms. Types A and B are caused by mutations in the SMPD1 gene (or acid sphingomyelinase), while type C is caused by mutations in the NPC1 or NPC2 genes. Both type A/B and C Niemann-Pick show increased plasma levels of LSM and/or its analog Lyso-sphingomyelin509 (LSM509), and it has been suggested that Niemann-Pick A and B can be biochemically distinguished from C by comparing plasma levels of LSM and LSM509. Niemann-Pick type C can also be specifically diagnosed by the levels of oxysterols in blood or plasma PMID: 28259515. Source: Regenstrief LOINC

LOINC Names Get Info

Fully-Specified Name: Lyso-sphingomyelin:SCnc:Pt:Bld:Qn:
Long Common Name: Lyso-sphingomyelin [Moles/volume] in Blood
Short Name: LSM Bld-sCnc
Display Name: Lyso-sphingomyelin (Bld) [Moles/Vol]
Consumer Name Alpha Get Info: Lyso-sphingomyelin, Blood

Part Model Get Info

Component
Lyso-sphingomyelin
LP310425-6
- Analyte
  Lyso-sphingomyelin
  LP310425-6
  - Component Numerator
    Lyso-sphingomyelin
    LP310425-6
    - Component Numerator Core
      Lyso-sphingomyelin
      LP310425-6
    - Component Numerator Core Suffix
      NULL
  - Component Denominator
    NULL
    - Component Denominator Core
      NULL
    - Component Denominator Core Suffix
      NULL
- Challenge
  NULL
- Adjustment
  NULL
- Count
  NULL
Property
SCnc
LP6860-3
Time
Pt
LP6960-1
- Time Core
  Pt
  LP6960-1
- Time Modifier
  NULL
System
Bld
LP7057-5
- System Core
  Bld
  LP7057-5
- Super System
  NULL
Scale
Qn
LP7753-9
Method
NULL

Basic Attributes

Class: CHEM
Type: Laboratory
First Released: Version 2.66
Last Updated: Version 2.66 (ADD)
Order vs. Observation: Observation

Member of these Panels

LOINC	Long Common Name
92738-4	Cholestane-3-beta, 5-alpha, 6-beta triol and Lyso-sphingomyelin panel - Blood
92744-2	Hepatosplenomegaly due to lysosomal storage disorders screening panel - Blood

Member of these Groups Get Info

LOINC Group	Group Name
LG50878-4	Lyso-sphingomyelin\|SCnc\|Pt\|ANYBldSerPl

Language Variants Get Info

Tag	Language	Translation
cs-CZ	Czech (Czechia)	Lyso-sfingomyelin:Látková koncentrace:Časový bod:Krev:Kvantitativní:
el-GR	Greek (Greece)	Λυσοσφιγγομυελίνη:SCnc:Pt:Αίμα:Qn: Synonyms: CHEM Pt Qn SCnc Αίμα Λυσοσφιγγομυελίνη Σφιγγομυελινάση
es-ES	Spanish (Spain)	Lisoesfingomielina:Concentración de sustancia:Punto temporal:Sangre:Qn: Synonyms: Cuantitativo
es-MX	Spanish (Mexico)	Liso-esfingomielina:Concentración de sustancias:Punto temporal:Sangre:Cuantitativo:
fr-FR	French (France)	Lyso-sphingomyéline:Moles/Volume:Ponctuel:Sang:Numérique:
it-IT	Italian (Italy)	Liso-sfingomielina:SCnc:Pt:Sangue:Qn: Synonyms: Chimica Concentrazione di Sostanza Punto nel tempo (episodio) Sangue
zh-CN	Chinese (China)	溶血鞘磷脂:物质的量浓度:时间点:全血:定量型: Synonyms: 克分子浓度;克分子浓度(单位体积);摩尔浓度;摩尔浓度(单位体积);物质的量浓度(单位体积) 化学;化学检验项目;化学检验项目类;化学类;化学试验;非刺激耐受型化学检验项目;非刺激耐受型化学检验项目类;非刺激耐受型化学试验;非刺激耐受型化学试验类可用数量表示的;定量性;数值型;数量型;连续数值型标尺时刻;随机;随意;瞬间神经磷脂;神经鞘骨磷脂;鞘磷脂神经鞘氨醇磷酸胆碱;Sphingosylphosphorylcholine;CAS 82970-80-7 血;血液

Example Units

Unit	Source
nmol/mL	Example UCUM Units

LOINC Terminology Service (API) using HL7^® FHIR^® Get Info

CodeSystem lookup: https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=92748-3

LOINC Copyright

Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.