LOINC
Version 2.73

92748-3Lyso-sphingomyelin [Moles/volume] in BloodActive

Part Description

LP310425-6   Lyso-sphingomyelin
Lyso-sphingomyelin (LSM, sphingosylphosphorylcholine) is a biomarker for Niemann-Pick disease types A, B and C, genetically distinct metabolic disorders. Niemann-Pick types A/B and C share clinical features including hepatospenomegaly and specific neurological symptoms. Types A and B are caused by mutations in the SMPD1 gene (or acid sphingomyelinase), while type C is caused by mutations in the NPC1 or NPC2 genes. Both type A/B and C Niemann-Pick show increased plasma levels of LSM and/or its analog Lyso-sphingomyelin509 (LSM509), and it has been suggested that Niemann-Pick A and B can be biochemically distinguished from C by comparing plasma levels of LSM and LSM509. Niemann-Pick type C can also be specifically diagnosed by the levels of oxysterols in blood or plasma [PMID:28259515]. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Regenstrief LOINC, Wikipedia

Fully-Specified Name

Component
Lyso-sphingomyelin
Property
SCnc
Time
Pt
System
Bld
Scale
Qn
Method

Additional Names

Short Name
LSM Bld-sCnc
Display Name
Lyso-sphingomyelin (Bld) [Moles/Vol]
Consumer Name Alpha
Lyso-sphingomyelin, Blood

Basic Attributes

Class
CHEM
Type
Laboratory
First Released
Version 2.66
Last Updated
Version 2.66
Order vs. Observation
Observation

Member of these Panels

LOINC Long Common Name
92738-4 Cholestane-3-beta, 5-alpha, 6-beta triol and Lyso-sphingomyelin panel - Blood
92744-2 Hepatosplenomegaly due to lysosomal storage disorders screening panel - Blood

Member of these Groups

LG50878-4 Lyso-sphingomyelin|SCnc|Pt|ANYBldSerPl

Language Variants Get Info

zh-CNChinese (China)
溶血鞘磷脂:物质的量浓度:时间点:全血:定量型:
fr-FRFrench (France)
Lyso-sphingomyéline:Moles/Volume:Ponctuel:Sang:Numérique:
it-ITItalian (Italy)
Liso-sfingomielina:SCnc:Pt:Sangue:Qn:
es-MXSpanish (Mexico)
Liso-esfingomielina:Concentración de sustancias:Punto temporal:Sangre:Cuantitativo:
es-ESSpanish (Spain)
Lisoesfingomielina:Concentración de sustancia:Punto temporal:Sangre:Qn:

Example Units

Unit Source
nmol/mL Example UCUM Units

LOINC FHIR® API Example - CodeSystem Request Get Info

https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=92748-3