Log In

Part Description

LP310354-8   7-Ketocholesterol
The oxidation products of cholesterol, particularly cholestane-3beta,5alpha,6beta-triol and 7-ketocholesterol, have proven to be sensitive and specific biomarkers for early detection of Niemann Pick type C (NPC) disease. NPC disease is a rare genetic disorder that results in the accumulation of cholesterol and other lipids internally. Patients often present in childhoold with hepatospenomegaly and central nervous system degeneration, although the presentation is broad and adult-onset psychiatric or visceral disease can occur. Mutations in the NPC1 or NPC2 gene are responsible, with the vast majority ocurring in NPC1. Prior to cholestane-3beta,5alpha,6beta-triol and 7-ketocholesterol, filipin staining of skin biopsy material was the assay of choice, although it was cumbersome, insensitive, and not widely avaialble PMID: 21518695. Source: Regenstrief LOINC

LOINC Names Get Info

Fully-Specified Name
7-Ketocholesterol:SCnc:Pt:Ser/Plas:Qn:
Long Common Name
7-Ketocholesterol [Moles/volume] in Serum or Plasma
Short Name
7-Ketochol SerPl-sCnc
Display Name
7-Ketocholesterol [Moles/Vol]
Consumer Name Alpha Get Info
7-Ketocholesterol, Blood

Part Model Get Info

  • Component
    7-Ketocholesterol
    LP310354-8
    • Analyte
      7-Ketocholesterol
      LP310354-8
      • Component Numerator
        7-Ketocholesterol
        LP310354-8
        • Component Numerator Core
          7-Ketocholesterol
          LP310354-8
        • Component Numerator Core Suffix
          NULL
           
      • Component Denominator
        NULL
         
        • Component Denominator Core
          NULL
           
        • Component Denominator Core Suffix
          NULL
           
    • Challenge
      NULL
       
    • Adjustment
      NULL
       
    • Count
      NULL
       
  • Property
    SCnc
    LP6860-3
  • Time
    Pt
    LP6960-1
  • System
    Ser/Plas
    LP7576-4
    • System Core
      Ser/Plas
      LP7576-4
    • Super System
      NULL
       
  • Scale
    Qn
    LP7753-9
  • Method
    NULL
     

Basic Attributes

Class
CHEM
Type
Laboratory
First Released
Version 2.66
Last Updated
Version 2.66 (ADD)
Order vs. Observation
Observation

Member of these Panels

LOINCLong Common Name
92740-0Oxysterols panel - Serum or Plasma

Language Variants Get Info

TagLanguageTranslation
cs-CZCzech (Czechia)7-ketocholesterol:Látková koncentrace:Časový bod:Sérum/plazma:Kvantitativní:
el-GRGreek (Greece)7-κετοχοληστερόλη:SCnc:Pt:Ορός/Πλάσμα:Qn:
Synonyms: 7-κετοχοληστερόλη CHEM Pt Qn SCnc Ορός Ορός/Πλάσμα Πλάσμα
es-ESSpanish (Spain)7-Ketocolesterol:Concentración de sustancia:Punto temporal:Suero o Plasma:Qn:
Synonyms: Cuantitativo
es-MXSpanish (Mexico)7-cetocolesterol:Concentración de sustancias:Punto temporal:Suero o Plasma:Cuantitativo:
fr-FRFrench (France)7-cétocholesterol:Moles/Volume:Ponctuel:Sérum/Plasma:Numérique:
it-ITItalian (Italy)7-Chetocolesterolo:SCnc:Pt:Siero/Plasma:Qn:
Synonyms: Chimica Concentrazione di Sostanza Plasma Punto nel tempo (episodio) Siero Siero o Plasma
pl-PLPolish (Poland)7-ketocholesterol:stężenie molowe:punkt w czasie:surowica lub osocze:ilościowy:
zh-CNChinese (China)7-酮基胆固醇:物质的量浓度:时间点:血清/血浆:定量型:
Synonyms: 7-酮胆固醇;7-Ketocholesterol;CAS 127684-08-6 克分子浓度;克分子浓度(单位体积);摩尔浓度;摩尔浓度(单位体积);物质的量浓度(单位体积) 化学;化学检验项目;化学检验项目类;化学类;化学试验;非刺激耐受型化学检验项目;非刺激耐受型化学检验项目类;非刺激耐受型化学试验;非刺激耐受型化学试验类 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 时刻;随机;随意;瞬间 血清或血浆

Example Units

UnitSource
nmol/mLExample UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=92764-0