Version 2.78

Term Description

This term is intended to report the number of CD64 molecules per neutrophil.
Source: Regenstrief LOINC

Part Descriptions

LP268943-0   CD64
CD64, also known as Fc gamma receptor I, is a transmembrane glycoprotein that is part of the large immunoglobulin (Ig) superfamily. CD64 is encoded by 3 genes (FCγRI A-C), one for the transmembrane region and the other 2 for the Ig-like domains. CD64 is consitutively expressed on monocytes and macrophages (but inducible on neutrophils), and it has a pivotal role in antibody-dependent cytotoxicity and clearance of immune complexes. The presence of this molecule on neutrophils can aid in the diagnosis of infection and sepsis, and immuotherapeutic agents targeting CD64 have emerged as candidates for treatment of chronic inflammatory diseases such as atopic dermatitis, rheumatoid arthritis, and autoimmune disorders PMID: 28895912. Source: Regenstrief LOINC

LP411252-2   Neutrophil
Neutrophils are the most common form of white blood cells in healthy adults. Neutrophils are approximately 13 micrometers in diameter and have segmented nuclei with 3-5 lobes that are connected by thin strands of chromatin. (Practical Haematology; Barbara J. Bain, Imelda Bates, Mike A. Laffan,S. Mitchell Lewis; Eleventh edition; 2012) Neutrophils function to fight infection by both engulfing microorganisms and secreting lethal enzymes.
(https://www.ncbi.nlm.nih.gov/pubmedhealth/PMHT0022058/) They are produced in the bone marrow and their primary function is to fight infection. Neutrophil numbers increase in the blood in response to acute bacterial infection, inflammation, necrosis or chronic myelogenous leukemia. Neutrophil levels are decreased in the following conditions: aplastic anemia, autoimmune disorder, cancer, chemotherapy, myelodysplastic syndrome and during a negative reaction to drugs. PMID: 24050624 [MedlinePlus Encyclopedia:19864] Source: Regenstrief LOINC

Fully-Specified Name

Component
CD64 Ag
Property
EntNum
Time
Pt
System
Neutrophil
Scale
Qn
Method
Flow cytometry

Additional Names

Long Common Name
CD64 Ag [Entitic number] on Neutrophil by Flow cytometry (FC)
Short Name
CD64 Ag EntNum Neut FC
Display Name
CD64 Ag FC (Neutrophil) [Entitic number]
Consumer Name Alpha Get Info
CD64 antigen, Neutrophil

Basic Attributes

Class
CELLMARK
Type
Laboratory
First Released
Version 2.67
Last Updated
Version 2.67
Order vs. Observation
Observation

Member of these Panels

LOINC Long Common Name
93354-9 Neutrophil CD64 and Monocyte HLA DR panel - Blood by Flow cytometry (FC)

Language Variants Get Info

Tag Language Translation
es-ES Spanish (Spain) CD64 Antígeno:Número entítico:Punto temporal:Neutrófilo:Qn:Citometria de flujo (FC)
Synonyms: Cuantitativo
es-MX Spanish (Mexico) CD64 Ag:Número entitic:Punto temporal:Neutrófilos:Cuantitativo:Citometría de flujo (FC)
fr-FR French (France) CD64 antigène:Nombre/entité:Ponctuel:Polynucléaires neutrophiles:Numérique:Cytométrie de flux
it-IT Italian (Italy) CD64, Ag:EntNum:Pt:Neutrofilo:Qn:Citometria a flusso
Synonyms: Citometria a flusso (FC) Modelli di superficie cellulare Numero entitico Punto nel tempo (episodio)
pl-PL Polish (Poland) CD64 Ag:liczba zawarta w:punkt w czasie:neutrofil:ilościowy:cytometria przepływowa (FC)
Synonyms: Antygen CD64 CD64
zh-CN Chinese (China) CD64 抗原:实体数量:时间点:嗜中性粒细胞:定量型:流式细胞测量术
Synonyms: Ag Fc gamma 受体 I FC gammaRI FC γ RI Fc γ受体 I Fc 受体 I FCR I 中性;中性粒;中性粒细胞;嗜中性 动态 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 实体计数 时刻;随机;随意;瞬间 流 流式细胞光度计;流式细胞测量术（Flow Cytometry，FC）;流式细胞计 细胞标志物

Example Units

Unit Source
{#}/{cell} Example UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=93353-1