93353-1

CD64 Ag [Entitic number] on Neutrophil by Flow cytometry (FC)

Active

Term Description

This term is intended to report the number of CD64 molecules per neutrophil.

Part Descriptions

LP268943-0 CD64
CD64, also known as Fc gamma receptor I, is a transmembrane glycoprotein that is part of the large immunoglobulin (Ig) superfamily. CD64 is encoded by 3 genes (FCγRI A-C), one for the transmembrane region and the other 2 for the Ig-like domains. CD64 is consitutively expressed on monocytes and macrophages (but inducible on neutrophils), and it has a pivotal role in antibody-dependent cytotoxicity and clearance of immune complexes. The presence of this molecule on neutrophils can aid in the diagnosis of infection and sepsis, and immuotherapeutic agents targeting CD64 have emerged as candidates for treatment of chronic inflammatory diseases such as atopic dermatitis, rheumatoid arthritis, and autoimmune disorders PMID: 28895912. Source: Regenstrief LOINC

LP411252-2 Neutrophil
Neutrophils are the most common form of white blood cells in healthy adults. Neutrophils are approximately 13 micrometers in diameter and have segmented nuclei with 3-5 lobes that are connected by thin strands of chromatin. (Practical Haematology; Barbara J. Bain, Imelda Bates, Mike A. Laffan,S. Mitchell Lewis; Eleventh edition; 2012) Neutrophils function to fight infection by both engulfing microorganisms and secreting lethal enzymes.
(https://www.ncbi.nlm.nih.gov/pubmedhealth/PMHT0022058/) They are produced in the bone marrow and their primary function is to fight infection. Neutrophil numbers increase in the blood in response to acute bacterial infection, inflammation, necrosis or chronic myelogenous leukemia. Neutrophil levels are decreased in the following conditions: aplastic anemia, autoimmune disorder, cancer, chemotherapy, myelodysplastic syndrome and during a negative reaction to drugs. PMID: 24050624 [MedlinePlus Encyclopedia:19864] Source: Regenstrief LOINC

LOINC Names Get Info

Fully-Specified Name: CD64 Ag:EntNum:Pt:Neutrophil:Qn:Flow cytometry
Long Common Name: CD64 Ag [Entitic number] on Neutrophil by Flow cytometry (FC)
Short Name: CD64 Ag EntNum Neut FC
Display Name: CD64 Ag FC (Neutrophil) [Entitic number]
Consumer Name Alpha Get Info: CD64 antigen, Neutrophil

Part Model Get Info

Component
CD64 Ag
LP410914-8
- Analyte
  CD64 Ag
  LP410914-8
  - Component Numerator
    CD64 Ag
    LP410914-8
    - Component Numerator Core
      CD64
      LP268943-0
    - Component Numerator Core Suffix
      Ag
      LP20666-1
  - Component Denominator
    NULL
    - Component Denominator Core
      NULL
    - Component Denominator Core Suffix
      NULL
- Challenge
  NULL
- Adjustment
  NULL
- Count
  NULL
Property
EntNum
LP6806-6
Time
Pt
LP6960-1
- Time Core
  Pt
  LP6960-1
- Time Modifier
  NULL
System
Neutrophil
LP411252-2
- System Core
  Neutrophil
  LP411252-2
- Super System
  NULL
Scale
Qn
LP7753-9
Method
Flow cytometry
LP6274-7

Basic Attributes

Class: CELLMARK
Type: Laboratory
First Released: Version 2.67
Last Updated: Version 2.67 (ADD)
Order vs. Observation: Observation

Member of these Panels

LOINC	Long Common Name
93354-9	Neutrophil CD64 and Monocyte HLA DR panel - Blood by Flow cytometry (FC)

Language Variants Get Info

Tag	Language	Translation
cs-CZ	Czech (Czechia)	CD64 Ag:Entitní počet:Časový bod:Neutrofil:Kvantitativní:Průtoková cytometrie
el-GR	Greek (Greece)	CD64 Αντιγόνο:EntNum:Pt:Ουδετερόφιλο:Qn:Κυτταρομετρία ροής Synonyms: CD64 CELLMARK EntNum Pt Qn Αντιγόνο Κυτταρομετρία ροής Ουδετερόφιλο
es-ES	Spanish (Spain)	CD64 Antígeno:Número entítico:Punto temporal:Neutrófilo:Qn:Citometria de flujo (FC) Synonyms: Cuantitativo
es-MX	Spanish (Mexico)	CD64 Ag:Número entitic:Punto temporal:Neutrófilos:Cuantitativo:Citometría de flujo (FC)
fr-FR	French (France)	CD64 Ag:Nombre/entité:Ponctuel:Polynucléaires neutrophiles:Numérique:Cytométrie de flux
it-IT	Italian (Italy)	CD64, Ag:EntNum:Pt:Neutrofilo:Qn:Citometria a flusso Synonyms: Citometria a flusso (FC) Modelli di superficie cellulare Numero entitico Punto nel tempo (episodio)
pl-PL	Polish (Poland)	CD64 Ag:liczba zawarta w:punkt w czasie:neutrofil:ilościowy:cytometria przepływowa (FC) Synonyms: Antygen CD64 CD64
zh-CN	Chinese (China)	CD64 抗原:实体数量:时间点:嗜中性粒细胞:定量型:流式细胞测量术 Synonyms: Ag Fc gamma 受体 I FC gammaRI FC γ RI Fc γ受体 I Fc 受体 I FCR I 中性;中性粒;中性粒细胞;嗜中性动态可用数量表示的;定量性;数值型;数量型;连续数值型标尺实体计数时刻;随机;随意;瞬间流流式细胞光度计;流式细胞测量术（Flow Cytometry，FC）;流式细胞计细胞标志物

Example Units

Unit	Source
{#}/{cell}	Example UCUM Units

LOINC Terminology Service (API) using HL7^® FHIR^® Get Info

CodeSystem lookup: https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=93353-1

LOINC Copyright

Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.