93502-3

NMDAR subunit 1 IgG Ab [Presence] in Cerebral spinal fluid by Cell binding immunofluorescent assay

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Part Descriptions

LP229977-6 N-methyl-D-aspartate receptor subunit 1
N-methyl-D-aspartate receptor 1 (NMDAR1) is subunit of NMDA receptors and belongs to the glutamate receptor channel superfamily. It is encoded by the GRIN1 (Glutamate [NMDA] receptor subunit zeta-1) gene located on chromosome 9q34.3.[UniProt: Q05586] Glutamate receptors are highly permeable to calcium and important for nervous system functioning. NMDAR1 antibodies are detected in patients with paraneoplastic syndromes, autoimmune encephalopathies and related conditions. Identification of specific antineuronal autoantibodies may direct evaluation for underlying malignancy. Characterization of autoantibody specificity may allow syndromic classification and assist in diagnosis and management. Source: Regenstrief LOINC

LP269367-1 CBA IFA
In cell binding assays or cell-based assays (CBA) also known as cell-based immunoassays, the DNA coding for a particular antigen is transfected into cultured cells, which are then used directly as substrate for antibody detection by immunofluorescence. The advantage of CBA IFA over conventional immunoassays is that purification and stability of the antigen is not required and they provide an in vivo substrate. Source: Regenstrief LOINC,

Fully-Specified Name

Component: N-methyl-D-aspartate receptor subunit 1 Ab.IgG
Property: PrThr
Time: Pt
System: CSF
Scale: Ord
Method: CBA IFA

Additional Names

Long Common Name: NMDAR subunit 1 IgG Ab [Presence] in Cerebral spinal fluid by Cell binding immunofluorescent assay
Short Name: NMDAR1 IgG CSF Ql CBA IFA
Display Name: NMDAR subunit 1 IgG Cell binding immunofluorescent assay Ql (CSF)
Consumer Name Alpha Get Info: NMDAR subunit 1 IgG antibody, Spinal fluid

Example Answer List: LL360-9

Source: Regenstrief Institute

Answer	Code	Score	Answer ID
PositiveCopyright http://snomed.info/sct ID:10828004 Positive (qualifier value)			LA6576-8
NegativeCopyright http://snomed.info/sct ID:260385009 Negative (qualifier value)			LA6577-6

Basic Attributes

Class: SERO
Type: Laboratory
First Released: Version 2.67
Last Updated: Version 2.69
Order vs. Observation: Both

Member of these Panels

LOINC	Long Common Name
94707-7	Dementia autoimmune Ab panel - Cerebral spinal fluid
94708-5	Encephalopathy autoimmune Ab panel - Cerebral spinal fluid
94709-3	Epilepsy autoimmune Ab panel - Cerebral spinal fluid
94712-7	Movement disorder autoimmune Ab panel - Cerebral spinal fluid
101416-6	Pediatric autoimmune central nervous system disorders evaluation panel - Cerebral spinal fluid

Language Variants Get Info

Tag	Language	Translation
es-ES	Spanish (Spain)	Subunidad 1 del receptor de N-metil-D-aspartato (NMDAR-1) IgG:PrThr:Punto temporal:Líquido Cefalorraquideo:Ord:CBA IFA (inmunofluorescencia indirecta de estudio basqado en células)
es-MX	Spanish (Mexico)	Subunidad 1 del receptor de N-metil-D-aspartato Ab.IgG:Presencia o umbral:Punto temporal:Fluído espinal cerebral:Ordinal:Ensayo inmunofluorescente de unión a células
fr-FR	French (France)	NMDAR1 anticorps IgG:Présence/Seuil:Ponctuel:Liquide céphalorachidien:Qualitatif:Immunofluorescence CBA
it-IT	Italian (Italy)	N-metil-D-aspartato, subunità 1 recettore Ab.IgG:PrThr:Pt:LCS:Ord:CBA IFA Synonyms: anticorpi IgG anticorpo Fluorescenza indiretta degli anticorpi (IFA) Liquido cerebrospinale Presenza o Soglia Punto nel tempo (episodio) Recettore dell''N-metil-D-aspartato; NMDAR Sierologia (anticorpi e la maggior parte degli ant Subunità 1 del recettore dell''N-metil-D-aspartato
zh-CN	Chinese (China)	N-甲基-D-天冬氨酸受体亚单位 1 抗体.IgG:存在情况或阈值:时间点:脑脊液:序数型:CBA IFA Synonyms: Ⅰ Ab.IgG;IgG;抗体 IgG Ab;自身抗体 Asp;天冬氨酸;门冬氨酸 CSF CSF;脊髓液;Cerebral spinal fluid;脑脊髓液 I N 型 N-甲基-D-天冬氨酸受体亚基 1;N-甲基-D-天门冬氨酸受体亚单位 1;N-甲基-D-天门冬氨酸受体亚基 1;NMDAR 亚单位 1;NMDAR 亚基 1 N-甲基-D-天门冬氨酸（Asp、天冬氨酸、门冬氨酸）受体 Rh;Rhesus;恒河猴;猕猴;罗猴依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型免疫球蛋白 G 存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值）时刻;随机;随意;瞬间细胞结合分析免疫荧光法;CBA IFA 法脊液脊髓液脑脊液（Cerebral spinal fluid，CSF）脑脊髓液血清;血清学;血清学检验项目;血清学检验项目 (非微生物学);血清学检验项目（非微生物学）;血清学检验项目类;血清学检验项目类 (非微生物学);血清学类;血清学类检验项目;血清学类检验项目 (非微生物学);血清学类试验;血清学类试验 (非微生物学);血清学试验;血清学试验 (非微生物学);血清学试验（非微生物学）;血清学试验类 (非微生物学);血清类间接荧光抗体间接荧光抗体试验

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Copyright © 2024 Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.