Version 2.77

Term Description

Detection of FOXO1 rearrangements with several translocation partners, including PAX3 and PAX7, by FISH analysis. FISH studies are shown to detect rearrangements not found by PCR, and they will often yield results when the quality of the specimen is poor or the PCR results are equivocal.
Source: Regenstrief LOINC

Part Descriptions

LP411838-8   FOXO1 gene rearrangements
FOXO1 (forkhead box O1) gene [HGNC ID: 3819] is located on chromosome 13 at position q14.11. The FOXO1 gene is part of the forkhead family of transcription factors but its specific function is not yet known. Gene rearrangements involving the FOXO1 are seen frequently in alveolar rhabdomyosarcoma (ARMS), an aggressive soft-tissue sarcoma. PMID: 19704258 Source: Regenstrief LOINC

LP62864-1   FISH
FISH (fluorescence in situ hybridization) is a cytogenetic technique used to detect and localize the presence or absence of specific DNA sequences on chromosomes. FISH uses fluorescent probes that bind to only those parts of the chromosome with which they show a high degree of sequence similarity. Fluorescence microscopy can be used to find out where the fluorescent probe bound to the chromosomes. FISH is often used for finding specific features in DNA for use in genetic counseling, medicine, and species identification. FISH can also be used to detect and localize specific mRNAs within tissue samples. In this context, it can help define the spatial-temporal patterns of gene expression within cells and tissues. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, FISH

Fully-Specified Name

Component
FOXO1 gene rearrangements
Property
Find
Time
Pt
System
Tiss
Scale
Doc
Method
FISH

Additional Names

Short Name
FOXO1 gene Rear Tiss FISH
Display Name
FOXO1 gene rearrangements FISH Doc (Tiss)
Consumer Name Alpha Get Info
FOXO1 gene rearrangements, Tissue

Basic Attributes

Class
MOLPATH
Type
Laboratory
First Released
Version 2.67
Last Updated
Version 2.67
Order vs. Observation
Both

Language Variants Get Info

Tag Language Translation
es-ES Spanish (Spain) Reordenamientos del gen FOXO1:Hallazgo:Punto temporal:Tejido:Doc:Hibridación in situ fluoresente (FISH)
es-MX Spanish (Mexico) Reordenamientos del gen FOXO1:Hallazgo:Punto temporal:Tejido y frotis:Documento:Hibridación fluorescente in situ (FISH)
fr-FR French (France) FOXO1 gène réarrangements:Recherche:Ponctuel:Tissu:Document:FISH
it-IT Italian (Italy) FOXO1, riarrangiamenti gene:Osservazione:Pt:Tessuto:Doc:FISH
Synonyms: Ibridazione in situ fluorescente (FISH) Osservazione Patologia molecolare Punto nel tempo (episodio) Riarrangiamenti gene FOXO1 Tessuto & Strisci
nl-NL Dutch (Netherlands) FOXO1-genherschikkingen:bevinding:moment:weefsel en uitstrijkjes:document:FISH
Synonyms: FOXO1-gentranslocaties
zh-CN Chinese (China) FOXO1 基因重排:发现:时间点:组织与涂片:文档型:FISH
Synonyms: FKH FKH1 Fluorescent in situ hybridization;荧光原位杂交 FOXO1 基因重排（重组） FOXO1A 临床文档型;临床文档;文档;文书;医疗文书;临床医疗文书 分子病理学;分子病理学试验 叉头型基因 O1A 叉头框 O1A 叉头框 O1A（Forkhead box O1A，FOXO1A） 叉头盒 O1A 发现是一个原子型临床观察指标，并不是作为印象的概括陈述。体格检查、病史、系统检查及其他此类观察指标的属性均为发现。它们的标尺对于编码型发现可能是名义型，而对于叙述型文本之中所报告的发现，则可能是叙述型。;发现物;所见;结果;结论 时刻;随机;随意;瞬间 未作说明的组织;组织;组织 & 涂片 横纹肌肉瘤之中的叉头型基因 横纹肌肉瘤之中的叉头框 横纹肌肉瘤之中的叉头盒 横纹肌肉瘤叉头型基因 横纹肌肉瘤叉头框 横纹肌肉瘤叉头盒 遗传基因;遗传因子;吉恩;生物基因

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=93807-6