93870-4
NMDAR subunit 1 Ab [Presence] in Serum by Cell binding immunofluorescent assay
Active
Part Descriptions
LP229977-6 N-methyl-D-aspartate receptor subunit 1
N-methyl-D-aspartate receptor 1 (NMDAR1) is subunit of NMDA receptors and belongs to the glutamate receptor channel superfamily. It is encoded by the GRIN1 (Glutamate [NMDA] receptor subunit zeta-1) gene located on chromosome 9q34.3.[UniProt: Q05586] Glutamate receptors are highly permeable to calcium and important for nervous system functioning. NMDAR1 antibodies are detected in patients with paraneoplastic syndromes, autoimmune encephalopathies and related conditions. Identification of specific antineuronal autoantibodies may direct evaluation for underlying malignancy. Characterization of autoantibody specificity may allow syndromic classification and assist in diagnosis and management.
Source: Regenstrief LOINC
LP269367-1 CBA IFA
In cell binding assays or cell-based assays (CBA) also known as cell-based immunoassays, the DNA coding for a particular antigen is transfected into cultured cells, which are then used directly as substrate for antibody detection by immunofluorescence. The advantage of CBA IFA over conventional immunoassays is that purification and stability of the antigen is not required and they provide an in vivo substrate.
Source: Regenstrief LOINC,
Fully-Specified Name
- Component
- N-methyl-D-aspartate receptor subunit 1 Ab
- Property
- PrThr
- Time
- Pt
- System
- Ser
- Scale
- Ord
- Method
- CBA IFA
Additional Names
- Short Name
- NMDAR1 Ab Ser Ql CBA IFA
- Display Name
- NMDAR subunit 1 Ab Cell binding immunofluorescent assay Ql (S)
- Consumer Name Alpha Get Info
- NMDAR subunit 1 antibody, Blood
Example Answer List: LL360-9
Source: Regenstrief InstituteAnswer | Code | Score | Answer ID |
---|---|---|---|
PositiveCopyright http://snomed.info/sct ID:10828004 Positive (qualifier value) | LA6576-8 | ||
NegativeCopyright http://snomed.info/sct ID:260385009 Negative (qualifier value) | LA6577-6 |
Basic Attributes
- Class
- SERO
- Type
- Laboratory
- First Released
- Version 2.67
- Last Updated
- Version 2.69
- Order vs. Observation
- Both
Member of these Groups Get Info
LOINC Group | Group Name |
---|---|
LG50948-5 | N-methyl-D-aspartate receptor subunit 1 Ab| |
Language Variants Get Info
Tag | Language | Translation |
---|---|---|
es-ES | Spanish (Spain) | Subunidad 1 del receptor de N-metil-D-aspartato (NMDAR-1) Anticuerpos: |
es-MX | Spanish (Mexico) | Subunidad del receptor de N-metil-D-aspartato 1 Ab: |
fr-FR | French (France) | NMDAR1 anticorps: |
it-IT | Italian (Italy) | N-metil-D-aspartato, subunità 1 recettore Ab: Synonyms: anticorpo Fluorescenza indiretta degli anticorpi (IFA) Presenza o Soglia Punto nel tempo (episodio) Recettore dell''N-metil-D-aspartato; |
zh-CN | Chinese (China) | N-甲基-D-天冬氨酸受体亚单位 1 抗体: Synonyms: Ⅰ Ab; |
LOINC Terminology Service (API) using HL7® FHIR® Get Info
Requests to this service require a free LOINC username and password. Below is a sample of the possible capabilities. See the LOINC Terminology Service documentation for more information.
- CodeSystem lookup
- https:
//fhir.loinc.org/CodeSystem/$lookup?system=http: //loinc.org&code=93870-4
Third Party Copyright
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LOINC Copyright
Copyright © 2024 Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright