Version 2.80

Term Description

Detection of IgG antibodies against cytosolic 5'-nucleotidase 1A (cN-1A; synonyms: Mup44, NT5C1A) in serum or plasma for the diagnosis of inclusion body myositis (IBM). The term was created for, but not limited in use to, the submitter's test kit, EUROIMMUN's Anti-cN-1A ELISA (IgG). A negative serological result does not exclude the presence of disease.

Part Description

LP411692-9   Cytosolic 5'-nucleotidase 1A
Cytosolic 5'-nucleotidase 1A (cN-1A; also known as Mup44, NT5C1A) antibodies are found in patients with inclusion body myositis (IBM), an autoimmune and degenerative disorder most common in persons 50 years or older. CN-1A is most abundant in skeletal muscle and is involved in a variety of functions, including DNA repair metabolism. Studies suggest that anti-cN1A autoimmunity may be a consequence of IBM myonuclear degeneration in patient. Anti-cN1A autoantibody testing may be useful in distinguishing IBM from polymyositis (PM) and other progressive muscular disorder that present with similar symptoms. PMID: 23596012 Source: Regenstrief LOINC

Fully-Specified Name

Component
Cytosolic 5'-nucleotidase 1A Ab.IgG
Property
PrThr
Time
Pt
System
Ser/Plas
Scale
Ord
Method
IA

Additional Names

Long Common Name
Cytosolic 5'-nucleotidase 1A IgG Ab [Presence] in Serum or Plasma by Immunoassay
Short Name
cN-1A IgG SerPl Ql IA
Display Name
Cytosolic 5'-nucleotidase 1A IgG IA Ql
Consumer Name Alpha Get Info
Cytosolic 5'-nucleotidase 1A IgG antibody, Blood

Example Answer List: LL360-9

Source: Regenstrief Institute
Answer Code Score Answer ID
PositiveCopyright http://snomed.info/sct ID:10828004 Positive (qualifier value) LA6576-8
NegativeCopyright http://snomed.info/sct ID:260385009 Negative (qualifier value) LA6577-6

Basic Attributes

Class
SERO
Type
Laboratory
First Released
Version 2.67
Last Updated
Version 2.67 (ADD)
Order vs. Observation
Both

Language Variants Get Info

Tag Language Translation
el-GR Greek (Greece) Κυτοσολική 5'-νουκλεοτιδάση 1Α Αντισώματα IgG:PrThr:Pt:Ορός/Πλάσμα:Ord:IA
Synonyms: 5''-Νουκλεοτιδάση PrThr Ανοσοσφαιρίνη G Κυτοσολική 5''-νουκλεοτιδάση 1Α
es-ES Spanish (Spain) 5'-nucleotidasa 1A citosólica IgG:PrThr:Punto temporal:Suero o Plasma:Ord:IA
es-MX Spanish (Mexico) 5'-nucleotidasa 1A citosólica Ab.IgG:Presencia o umbral:Punto temporal:Suero o Plasma:Ordinal:Inmunoensayo
fr-FR French (France) CN1-A anticorps IgG:Présence/Seuil:Ponctuel:Sérum/Plasma:Qualitatif:Immunoanalyse
it-IT Italian (Italy) Citolosica 5'-nucleotidasi 1A Ab.IgG:PrThr:Pt:Siero/Plasma:Ord:IA
Synonyms: 5'' nucleotidasi citosolica 1A anticorpi IgG anticorpo Immunoassay Plasma Presenza o Soglia Punto nel tempo (episodio) Siero Siero o Plasma Sierologia (anticorpi e la maggior parte degli ant
zh-CN Chinese (China) 胞质-5'-核苷酸酶 1A 抗体.IgG:存在情况或阈值:时间点:血清/血浆:序数型:免疫测定法
Synonyms: 5NT;5''-NT;NT Ab.IgG;IgG;抗体 IgG Ab;自身抗体 依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型 免疫测定;免疫分析法;免疫检定法;免疫检定;免疫试验;酶免疫测定法;酶免疫测定;酶免疫分析法;酶免疫检定法;酶免疫检定;酶免疫试验 免疫球蛋白 G 存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值） 时刻;随机;随意;瞬间 胞浆-5''-核苷酸酶 1A;CN-1A 血清;血清学;血清学检验项目;血清学检验项目 (非微生物学);血清学检验项目（非微生物学）;血清学检验项目类;血清学检验项目类 (非微生物学);血清学类;血清学类检验项目;血清学类检验项目 (非微生物学);血清学类试验;血清学类试验 (非微生物学);血清学试验;血清学试验 (非微生物学);血清学试验（非微生物学）;血清学试验类 (非微生物学);血清类 血清或血浆

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