9418-5

Hydroxybupropion [Mass/volume] in Serum or Plasma

Active

Part Description

LP17880-3 Hydroxybupropion
Hydroxybupropion, also known as 6-hydroxybupropion and BW 306U, is the major active metabolite of the antidepressant and smoking cessation drug bupropion. It is formed from bupropion by the enzyme CYP2B6. With oral bupropion treatment, hydroxybupropion is present in plasma at area under the curve concentrations that are as many as 16 times greater than those of bupropion itself, demonstrating extensive first-pass metabolism of bupropion into hydroxybupropion in humans. As such, hydroxybupropion is likely to play a very important role in the effects of oral bupropion, which could be accurately thought of as functioning in large part as a prodrug to hydroxybupropion. [Wikipedia: Hydroxybupropion] Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Hydroxybupropion

LOINC Names Get Info

Fully-Specified Name: Hydroxybupropion:MCnc:Pt:Ser/Plas:Qn:
Long Common Name: Hydroxybupropion [Mass/volume] in Serum or Plasma
Short Name: OH-bupropion SerPl-mCnc
Display Name: Hydroxybupropion [Mass/Vol]
Consumer Name Alpha Get Info: Hydroxybupropion, Blood

Part Model Get Info

Component
Hydroxybupropion
LP17880-3
- Analyte
  Hydroxybupropion
  LP17880-3
  - Component Numerator
    Hydroxybupropion
    LP17880-3
    - Component Numerator Core
      Hydroxybupropion
      LP17880-3
    - Component Numerator Core Suffix
      NULL
  - Component Denominator
    NULL
    - Component Denominator Core
      NULL
    - Component Denominator Core Suffix
      NULL
- Challenge
  NULL
- Adjustment
  NULL
- Count
  NULL
Property
MCnc
LP6827-2
Time
Pt
LP6960-1
- Time Core
  Pt
  LP6960-1
- Time Modifier
  NULL
System
Ser/Plas
LP7576-4
- System Core
  Ser/Plas
  LP7576-4
- Super System
  NULL
Scale
Qn
LP7753-9
Method
NULL

Basic Attributes

Class: DRUG/TOX
Type: Laboratory
First Released: Version 1.0i
Last Updated: Version 2.73 (MIN)
Order vs. Observation: Both
Common Test Rank Get Info: 9881

Member of these Groups Get Info

LOINC Group	Group Name
LG24944-7	Hydroxybupropion\|MCnc\|Pt\|ANYBldSerPl
LG48796-3	Hydroxybupropion\|Pt\|Ser/Plas

Language Variants Get Info

Tag	Language	Translation
cs-CZ	Czech (Czechia)	Hydroxybupropion:Hmotnostní koncentrace:Časový bod:Sérum/plazma:Kvantitativní:
de-AT	German (Austria)	Synonyms: Hydroxybupropion
el-GR	Greek (Greece)	Υδροξυβουπροπιόνη:MCnc:Pt:Ορός/Πλάσμα:Qn: Synonyms: DRUG/TOX MCnc Pt Qn Ορός Ορός/Πλάσμα Πλάσμα Υδροξυβουπροπιόνη
es-AR	Spanish (Argentina)	hidroxibupropión:concentración de masa:punto en el tiempo:suero/plasma:cuantitativo:
es-ES	Spanish (Spain)	Hidroxibupropión:Concentración de masa:Punto temporal:Suero o Plasma:Qn: Synonyms: Cuantitativo
es-MX	Spanish (Mexico)	Hidroxibupropión:Concentración de masa:Punto temporal:Suero o Plasma:Cuantitativo:
et-EE	Estonian (Estonia)	Hüdroksübupropioon:MCnc:Pt:S/P:Qn: Synonyms: Juhuslik Kvantitatiivne Plasma Seerum Seerum või plasma
fr-CA	French (Canada)	Hydroxybupropione:Concentration de masse:Temps ponctuel:Sérum/Plasma:Quantitatif:
fr-FR	French (France)	Hydroxybupropion:Masse/Volume:Ponctuel:Sérum/Plasma:Numérique:
fr-BE	French (Belgium)	Hydroxybupropione:Concentration de masse:Temps ponctuel:Sérum/Plasma:Quantitatif:
it-IT	Italian (Italy)	Idrossibupropione:MCnc:Pt:Siero/Plasma:Qn: Synonyms: Concentrazione di Massa Livelli farmacologici e tossicologia Plasma Punto nel tempo (episodio) Siero Siero o Plasma
ko-KR	Korean (Korea, Republic Of)	Hydroxybupropion:질량농도:검사시점:혈청/혈장:정량:
nl-NL	Dutch (Netherlands)	hydroxybupropion:massa/volume:moment:serum of plasma:kwantitatief:
pl-PL	Polish (Poland)	Hydroksybupropion:stężenie masowe:punkt w czasie:surowica lub osocze:ilościowy:
pt-BR	Portuguese (Brazil)	Hidroxibupropiona:MCnc:Pt:Sor/Plas:Qn: Synonyms: ; OH-Bupropion; Mass concentration; Level; Point in time; Random; SerPl; SerPlas; SerP; Serum; SR; Plasma; Pl; Plsm; Quantitative; QNT; Quant; Quan; Drugs; DRUG/TOXICOLOGY; DRUG/TOXICOLOGY
ru-RU	Russian (Russian Federation)	Гидроксибупропион:МассКонц:ТчкВрм:Сыв/Плаз:Колич: Synonyms: Количественный Массовая концентрация Плазма Сыворотка Сыворотка или Плазма Точка во времени;Момент
tr-TR	Turkish (Turkey)	Hidroksibupropion:KütlKons:Zmlı:Ser/Plaz:Kant:
zh-CN	Chinese (China)	羟基丁氨苯丙酮:质量浓度:时间点:血清/血浆:定量型: Synonyms: 可用数量表示的;定量性;数值型;数量型;连续数值型标尺时刻;随机;随意;瞬间毒品毒品类水平;浓度;质量浓度(单位体积) 药品类药物药物/毒理学;药物/毒理学试验;药物毒理学试验;药物毒理学试验类药物类血清或血浆

Example Units

Unit	Source
ng/mL	Example UCUM Units

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LOINC Copyright

Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.