94216-9
STK11 gene deletion+duplication and full mutation analysis in Blood or Tissue by Molecular genetics method
Active
Term Description
Test includes full sequence analysis (e.g. by Sanger and/or next-generation sequencing) and deletion/duplication analysis for the detection of variants and large deletions/duplications in the STK11 gene to confirm a diagnosis of Peutz-Jeghers syndrome (PJS), an autosomal dominant disorder characterized by hamartomatous polyps in the gastrointestinal tract, pigmented macules on the skin and mouth, and other neoplasms.[GHR gene: STK11]
Source: Regenstrief LOINC
Part Description
LP71163-7 STK11 gene
The STK11 gene (serine/threonine kinase 11) [HGNC Gene ID:11389] is located on chromosome 19p13.3. This gene, which encodes a member of the serine/threonine kinase family, regulates cell polarity and functions as a tumor suppressor. Mutations in this gene have been associated with Peutz-Jeghers syndrome, an autosomal dominant disorder characterized by the growth of polyps in the gastrointestinal tract, pigmented macules on the skin and mouth, and other neoplasms. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. [provided by RefSeq, Jul 2008] [NCBI Gene ID:6794]
Source: National Center for Biotechnology Information (NCBI) Gene
Fully-Specified Name
- Component
- STK11 gene deletion+duplication & full mutation analysis
- Property
- Find
- Time
- Pt
- System
- Bld/Tiss
- Scale
- Doc
- Method
- Molgen
Additional Names
- Short Name
- STK11 gene Del+Dup + Full Mut Anl Bld/T
- Display Name
- STK11 gene del+dup and full mutation analysis Molgen Doc (Bld/Tiss)
- Consumer Name Alpha Get Info
- STK11 gene variant analysis, Blood or tissue specimen
Basic Attributes
- Class
- MOLPATH
- Type
- Laboratory
- First Released
- Version 2.68
- Last Updated
- Version 2.68
- Order vs. Observation
- Both
Language Variants Get Info
Tag | Language | Translation |
---|---|---|
es-ES | Spanish (Spain) | Gen STK11 estudio delecion+duplicacion y estudio mutacional completo: |
es-MX | Spanish (Mexico) | Eliminación del gen STK11 + análisis de duplicación y mutación completa: |
fr-FR | French (France) | STK11 gène délétion+duplication et analyse complète des mutations: |
it-IT | Italian (Italy) | STK11, gene Delezione+duplicazione & analisi di mutazione completa: Synonyms: delezione e duplicazione Gene STK11 Genetica molecolare Osservazione Patologia molecolare Punto nel tempo (episodio) Sangue Sangue o Tessuto Tessuto & |
nl-NL | Dutch (Netherlands) | STK11-gen deletie + duplicatie & volledige mutatie analyse: Synonyms: molgen STK11 gen |
tr-TR | Turkish (Turkey) | STK11 geni delesyon+duplikasyon ve tam mutasyon analizi: Synonyms: çiftleme |
zh-CN | Chinese (China) | STK11 基因 缺失+重复与全面的突变分析: Synonyms: LKB1; |
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