94286-2

Contactin-associated protein 2 IgG Ab [Presence] in Cerebrospinal Fluid by Cell binding immunofluorescent assay

Active

Part Descriptions

LP230270-3 Contactin-associated protein 2
Contactin-associated protein 2 (CASPR2) is present in the axons of the granule neurons of the cerebellum and the juxtaparanodal region of myelinated axons. Increased titers of CASPR2 antibodies were first discovered in patients with Morvan's syndrome. Symptoms of Morvan's syndrome include neuromyotonia, insomnia, autonomic dysfunction and neuropathic pain. Though CASPR2 antibodies have been found in 10% of patients with idiopathic cerebellar ataxia, no specific disease has been attributed to patients with the rare occurrence of positive antibodies for CASPR2 with cerebellar involvement. PMID: 25846566 Source: Regenstrief LOINC

LP269367-1 CBA IFA
In cell binding assays or cell-based assays (CBA) also known as cell-based immunoassays, the DNA coding for a particular antigen is transfected into cultured cells, which are then used directly as substrate for antibody detection by immunofluorescence. The advantage of CBA IFA over conventional immunoassays is that purification and stability of the antigen is not required and they provide an in vivo substrate. Source: Regenstrief LOINC,

LOINC Names Get Info

Fully-Specified Name: Contactin-associated protein 2 Ab.IgG:PrThr:Pt:CSF:Ord:CBA IFA
Long Common Name: Contactin-associated protein 2 IgG Ab [Presence] in Cerebrospinal Fluid by Cell binding immunofluorescent assay
Short Name: CASPR2 IgG CSF Ql CBA IFA
Display Name: Contactin-associated protein 2 IgG Cell binding immunofluorescent assay Ql (CSF)
Consumer Name Alpha Get Info: Contactin-associated protein 2 IgG antibody, Spinal fluid

Part Model Get Info

Component
Contactin-associated protein 2 Ab.IgG
LP232466-5
- Analyte
  Contactin-associated protein 2 Ab.IgG
  LP232466-5
  - Component Numerator
    Contactin-associated protein 2 Ab.IgG
    LP232466-5
    - Component Numerator Core
      Contactin-associated protein 2
      LP230270-3
    - Component Numerator Core Suffix
      Ab.IgG
      LP32401-9
  - Component Denominator
    NULL
    - Component Denominator Core
      NULL
    - Component Denominator Core Suffix
      NULL
- Challenge
  NULL
- Adjustment
  NULL
- Count
  NULL
Property
PrThr
LP217195-9
Time
Pt
LP6960-1
- Time Core
  Pt
  LP6960-1
- Time Modifier
  NULL
System
CSF
LP7156-5
- System Core
  CSF
  LP7156-5
- Super System
  NULL
Scale
Ord
LP7751-3
Method
CBA IFA
LP269367-1

Example Answer List: LL360-9

Source: Regenstrief Institute

Answer	Code	Score	Answer ID
PositiveCopyright http://snomed.info/sct ID:10828004 Positive (qualifier value)			LA6576-8
NegativeCopyright http://snomed.info/sct ID:260385009 Negative (qualifier value)			LA6577-6

Basic Attributes

Class: SERO
Type: Laboratory
First Released: Version 2.68
Last Updated: Version 2.83 (MIN)
Order vs. Observation: Both

Member of these Panels

LOINC	Long Common Name
94707-7	Dementia autoimmune Ab panel - Cerebrospinal Fluid
94708-5	Encephalopathy autoimmune Ab panel - Cerebrospinal Fluid
94709-3	Epilepsy autoimmune Ab panel - Cerebrospinal Fluid
94712-7	Movement disorder autoimmune Ab panel - Cerebrospinal Fluid
101416-6	Pediatric autoimmune central nervous system disorders evaluation panel - Cerebrospinal Fluid

Member of these Groups Get Info

LOINC Group	Group Name
LG50959-2	Contactin-associated protein 2 Ab.IgG\|PrThr\|Pt\|CSF

Language Variants Get Info

Tag	Language	Translation
cs-CZ	Czech (Czechia)	Kontaktin asociovaný protein 2 IgG:Přítomnost nebo práh:Časový bod:Mozkomíšní mok:Ordinální:CBA imunofluorescenční test
el-GR	Greek (Greece)	Πρωτεΐνη 2 που σχετίζεται με την κοντακτίνη Αντισώματα IgG:PrThr:Pt:ΕΝΥ:Ord:CBA IFA Synonyms: CBA IFA Ord PrThr Pt SERO Ανοσοσφαιρίνη G Αντίσωμα Αντισώματα IgG ΕΝΥ Πρωτεΐνη Πρωτεΐνη 2 που σχετίζεται με την κοντακτίνη
es-ES	Spanish (Spain)	Proteína 2 asociada a contactina IgG:PrThr:Punto temporal:Líquido Cefalorraquideo:Ord:CBA IFA (inmunofluorescencia indirecta de estudio basqado en células)
es-MX	Spanish (Mexico)	Proteína 2 Ab.IgG asociada a contactina:Presencia o umbral:Punto temporal:Fluído espinal cerebral:Ordinal:Ensayo inmunofluorescente de unión a células
fr-FR	French (France)	CASPR2 Ac IgG:Présence/Seuil:Ponctuel:Liquide céphalorachidien:Qualitatif:Immunofluorescence CBA
it-IT	Italian (Italy)	Proteina 2 Contactin-associata Ab.IgG:PrThr:Pt:LCS:Ord:CBA IFA Synonyms: anticorpi IgG anticorpo CNTNAP2 Fluorescenza indiretta degli anticorpi (IFA) Liquido cerebrospinale Presenza o Soglia Punto nel tempo (episodio) Sierologia (anticorpi e la maggior parte degli ant
pl-PL	Polish (Poland)	Białko związane z kontaktyną 2 Ab.IgG:granica wykrywalności:punkt w czasie:płyn mózgowo-rdzeniowy:uporządkowany:test immunofluorescencji pośredniej (z wykorzystaniem komórek) Synonyms: CASPR2 IgG Przeciwciała do białka związanemu z kontaktyną typu 2 przeciwciała IgG Przeciwciała IgG do białka związanego z kontaktyną typu 2
zh-CN	Chinese (China)	接触蛋白关联蛋白 2 抗体.IgG:存在情况或阈值:时间点:脑脊液:序数型:CBA IFA Synonyms: Ⅱ Ab.IgG;IgG;抗体 IgG Ab;自身抗体 CASPR2;接触蛋白相关蛋白 2;接触素关联蛋白 2;接触素相关蛋白 2 CSF CSF;脊髓液;Cerebral spinal fluid;脑脊髓液 II PR;Prot;成分 - 化学 - 蛋白质类;蛋白;朊;蛋白质类;蛋白质类物质依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型免疫球蛋白 G 关联的存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值）时刻;随机;随意;瞬间有联系的相关的细胞结合分析免疫荧光法;CBA IFA 法脊液脊髓液脑脊液（Cerebral spinal fluid，CSF）脑脊髓液血清;血清学;血清学检验项目;血清学检验项目 (非微生物学);血清学检验项目（非微生物学）;血清学检验项目类;血清学检验项目类 (非微生物学);血清学类;血清学类检验项目;血清学类检验项目 (非微生物学);血清学类试验;血清学类试验 (非微生物学);血清学试验;血清学试验 (非微生物学);血清学试验（非微生物学）;血清学试验类 (非微生物学);血清类间接荧光抗体间接荧光抗体试验

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LOINC Copyright

Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.