LOINC
Version 2.71

94306-8SARS-CoV-2 (COVID-19) RNA panel - Specimen by NAA with probe detectionActive

Term Description

This panel contains results for the detection of Severe acute respiratory syndrome (SARS) coronavirus 2 (SARS-CoV-2), initially known as 2019-Novel Coronavirus (2019-nCoV), in various specimens, including respiratory and serum, using nucleic acid amplification assays with probe-based detection for the diagnosis of Coronavirus Disease 2019 (COVID-19). Various assays have been developed that contain primer-probe sets targeting regions of the SARS-CoV-2 genome, including regions in the RdRp, N, and E genes. [https://www.who.int/emergencies/diseases/novel-coronavirus-2019/technical-guidance/laboratory-guidance] The CDC-developed SARS-CoV-2 assay contains primer and probe sets designed for specific detection of SARS-CoV-2 (N1 and N2 assays) as well as detection of the SARS-like coronaviruses (N3 assay).[CDC:coronavirus/2019-nCoV/lab/]
Source: Regenstrief LOINC

Part Description

LP417539-6   SARS coronavirus 2 RNA panel
The Severe acute respiratory syndrome (SARS) coronavirus 2 (SARS-CoV-2), first known as 2019 Novel Coronavirus (2019-nCoV), was first identified as the cause of a respiratory illness outbreak, later defined as Coronavirus Disease 2019 (COVID-19), in Wuhan, China. The full genome of the SARS-CoV-2 that causes COVID-19 was first posted by Chinese health authorities in GenBank, the NIH genetic sequence database, and in the Global Initiative on Sharing All Influenza Data (GISAI) portal. This facilitated detection of the virus globally with subsequent sequences being nearly identical, suggesting a single, recent emergence from a virus related to bat coronaviruses and the SARS coronavirus. Real time Reverse Transcription-Polymerase Chain Reaction (rRT-PCR) tests targeting regions within genes, including RdRp, S, N, M, and E genes, specific to SARS-CoV-2 have been developed by the Centers for Disease Control and Prevention (CDC), the World Health Organization (WHO) and others for the diagnosis of COVID-19. Some assays only detect SARS-CoV-2 and other assays detect other strains (e.g. SARS-CoV) that are genetically similar.[CDC:coronavirus/2019-ncov][https://www.who.int/emergencies/diseases/novel-coronavirus-2019/technical-guidance/laboratory-guidance] Source: Regenstrief LOINC

Panel Hierarchy
Details for each LOINC in Panel LHC-Forms

LOINC Name R/O/C Cardinality Example UCUM Units
94306-8 SARS-CoV-2 (COVID-19) RNA panel - Specimen by NAA with probe detection
Indent94312-6 SARS-CoV-2 (COVID-19) N gene [Cycle Threshold #] in Specimen by Nucleic acid amplification using CDC primer-probe set N2 {Ct_value}
Indent94311-8 SARS-CoV-2 (COVID-19) N gene [Cycle Threshold #] in Specimen by Nucleic acid amplification using CDC primer-probe set N1 {Ct_value}
Indent94510-5 SARS-CoV-2 (COVID-19) N gene [Cycle Threshold #] in Specimen by NAA with probe detection {Ct_value}
Indent94308-4 SARS-CoV-2 (COVID-19) N gene [Presence] in Specimen by Nucleic acid amplification using CDC primer-probe set N2
Indent94316-7 SARS-CoV-2 (COVID-19) N gene [Presence] in Specimen by NAA with probe detection
Indent94307-6 SARS-CoV-2 (COVID-19) N gene [Presence] in Specimen by Nucleic acid amplification using CDC primer-probe set N1
Indent94511-3 SARS-CoV-2 (COVID-19) ORF1ab region [Cycle Threshold #] in Specimen by NAA with probe detection {Ct_value}
Indent94639-2 SARS-CoV-2 (COVID-19) ORF1ab region [Presence] in Specimen by NAA with probe detection
Indent94314-2 SARS-CoV-2 (COVID-19) RdRp gene [Presence] in Specimen by NAA with probe detection
Indent94645-9 SARS-CoV-2 (COVID-19) RdRp gene [Cycle Threshold #] in Specimen by NAA with probe detection {Ct_value}
Indent94643-4 SARS-CoV-2 (COVID-19) S gene [Cycle Threshold #] in Specimen by NAA with probe detection {Ct_value}
Indent94641-8 SARS-CoV-2 (COVID-19) S gene [Presence] in Specimen by NAA with probe detection
Indent94309-2 SARS-CoV-2 (COVID-19) RNA [Presence] in Specimen by NAA with probe detection
Indent94746-5 SARS-CoV-2 (COVID-19) RNA [Cycle Threshold #] in Specimen by NAA with probe detection {Ct_value}
Indent94819-0 SARS-CoV-2 (COVID-19) RNA [Log #/volume] (viral load) in Specimen by NAA with probe detection {Log_copies}/mL
Indent94315-9 SARS-related coronavirus E gene [Presence] in Specimen by NAA with probe detection
Indent94509-7 SARS-related coronavirus E gene [Cycle Threshold #] in Specimen by NAA with probe detection {Ct_value}
Indent94647-5 SARS-related coronavirus RNA [Presence] in Specimen by NAA with probe detection
Indent94313-4 SARS-related coronavirus N gene [Cycle Threshold #] in Specimen by Nucleic acid amplification using CDC primer-probe set N3 {Ct_value}
Indent94310-0 SARS-related coronavirus N gene [Presence] in Specimen by Nucleic acid amplification using CDC primer-probe set N3

Fully-Specified Name

Component
SARS coronavirus 2 RNA panel
Property
-
Time
Pt
System
XXX
Scale
-
Method
Probe.amp.tar

Additional Names

Short Name
SARS-CoV-2 RNA Pnl Spec NAA+probe
Display Name
SARS-CoV-2 (COVID-19) RNA panel NAA+probe (Specimen)
Consumer Name Alpha
SARS-CoV-2 (COVID-19) RNA Panel, Specimen

Ask At Order Entry

This panel contains a convenience grouping of terms for questions commonly asked when an order is placed in a public health laboratory.

LOINC Name R/O/C Cardinality Example UCUM Units
81959-9 Public health laboratory ask at order entry panel
Indent81744-5 Submitter's laboratory test method [Type] in Specimen
Indent81658-7 Suspected organism [Identifier] in Specimen
Indent86952-9 Preliminary testing done Specimen
Indent86953-7 Preliminary testing result Specimen
Indent86955-2 Preliminary testing affected submission for further testing Specimen
Indent95417-2 Whether this is the patient's first test for condition of interest
Indent95418-0 Whether patient is employed in a healthcare setting
Indent95419-8 Whether the patient has symptoms related to condition of interest
Indent11368-8 Illness or injury onset date and time C
Indent77974-4 Whether the patient was hospitalized for condition of interest
Indent95420-6 Whether the patient was admitted to intensive care unit (ICU) for condition of interest
Indent95421-4 Whether patient resides in a congregate care setting
Indent82810-3 Pregnancy status C
Indent30525-0 Age a

Basic Attributes

Class
PANEL.MICRO
Type
Laboratory
First Released
Version 2.68
Last Updated
Version 2.69
Order vs. Observation
Order
Panel Type
Panel

Reference Information

Type Source Reference
Package Insert Centers for Disease Control and Prevention This document describes the use of real-time RT PCR (rRT-PCR) assays for the in vitro qualitative detection of 2019-Novel Coronavirus (2019-nCoV) in respiratory specimens and sera. The 2019-nCoV primer and probe sets are designed for the universal detection of SARS-like coronaviruses (N3 assay) and for specific detection of 2019-nCoV (N1 and N2 assays). Real-Time RT-PCR Panel for Detection 2019-Novel Coronavirus
Package Insert World Health Organization (WHO)Copyright Copyright © 2001 World Health Organization. Diagnostic detection of 2019-nCoV by real-time RT-PCR

Member of these Groups

LG51017-8 SARSCoV2 detection
LG51019-4 SARSCoV2 molecular detection

Language Variants Get Info

zh-CNChinese (China)
SARS 冠状病毒 2 RNA 组套:-:时间点:XXX:-:探针法.基因扩增.靶向
nl-NLDutch (Netherlands)
SARS-CoV-2 RNA panel:-:moment:XXX:-:moleculaire techniek (PCR)
fr-CAFrench (Canada)
Coronavirus 2 du SRAS, ARN:-:Temps ponctuel:XXX:-:Sonde avec amplification de la cible
fr-FRFrench (France)
Coronavirus SARS-CoV-2 ARN panel:-:Ponctuel:Milieux divers:-:PCR amplification de cible
it-ITItalian (Italy)
SARS coronavirus 2, panel RNA:-:Pt:XXX:-:Sonda.amp.tar
es-ESSpanish (Spain)
Panel de ARN del SARS-CoV-2 (COVID-19):Propiedades mixtas (sólo paneles):Punto temporal:XXX:-:Sonda con amplificación dirigida

LOINC FHIR® API Example - CodeSystem and Questionnaire Requests Get Info

https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=94306-8 https://fhir.loinc.org/Questionnaire/?url=http://loinc.org/q/94306-8