94358-9

Neuronal nuclear type 3 IgG Ab [Titer] in Cerebrospinal Fluid by Immunofluorescence

Active

Part Description

LP31707-0 Neuronal nuclear type 3
Neuronal nuclear type 3 Ab (ANNA-3) is one of three neuronal nuclear paraneoplastic antibodies that primarily binds to the nuclei of cerebellar Purkinje neurons and to renal glomerular podocytes. Symptoms of the presence of ANNA-3 include sensory or sensorimotor neuropathies, cerebellar ataxia, myelopathy, brain stem and limbic encephalopathy.It's presence in serum is most commonly indicative of a small-cell malignant tumor, most of which are primary tumors of the lung.Fluorescent staining patterns are used to distinguish ANNA-3 from the other two neuronal nuclear types, ANNA-1 and ANNA-2. ANNA-3 binds the nuclei of Purkinje neurons in the cerebellar cortex more than the molecular neurons, and does not bind granular neurons. ANNA-3 binds only the nuclei of indentate neurons, while ANNA-1 and ANNA-2 bind both the nuclei and cytoplasm of all neurons. ANNA-3 binds the nuclei of glomuerular podocytes in of the renal cortex in 10 of 11 sera. For the same cell type, ANNA-2 binds both the nuclei and cytoplasm in 8 of 32 sera, and ANNA-1 does not bind the podocytes at all. PMID: 11558786 Source: Regenstrief LOINC

LOINC Names Get Info

Fully-Specified Name: Neuronal nuclear type 3 Ab.IgG:Titr:Pt:CSF:SemiQn:IF
Long Common Name: Neuronal nuclear type 3 IgG Ab [Titer] in Cerebrospinal Fluid by Immunofluorescence
Short Name: Hu3 IgG Titr CSF IF
Display Name: Neuronal nuclear type 3 IgG IF (CSF) [Titer]
Consumer Name Alpha Get Info: Neuronal nuclear type 3 IgG antibody, Spinal fluid

Part Model Get Info

Component
Neuronal nuclear type 3 Ab.IgG
LP417807-7
- Analyte
  Neuronal nuclear type 3 Ab.IgG
  LP417807-7
  - Component Numerator
    Neuronal nuclear type 3 Ab.IgG
    LP417807-7
    - Component Numerator Core
      Neuronal nuclear type 3
      LP31707-0
    - Component Numerator Core Suffix
      Ab.IgG
      LP32401-9
  - Component Denominator
    NULL
    - Component Denominator Core
      NULL
    - Component Denominator Core Suffix
      NULL
- Challenge
  NULL
- Adjustment
  NULL
- Count
  NULL
Property
Titr
LP6881-9
Time
Pt
LP6960-1
- Time Core
  Pt
  LP6960-1
- Time Modifier
  NULL
System
CSF
LP7156-5
- System Core
  CSF
  LP7156-5
- Super System
  NULL
Scale
SemiQn
LP436123-6
Method
IF
LP6323-2

Basic Attributes

Class: SERO
Type: Laboratory
First Released: Version 2.68
Last Updated: Version 2.83 (MIN)
Order vs. Observation: Both

Member of these Panels

LOINC	Long Common Name
94707-7	Dementia autoimmune Ab panel - Cerebrospinal Fluid
94708-5	Encephalopathy autoimmune Ab panel - Cerebrospinal Fluid
94709-3	Epilepsy autoimmune Ab panel - Cerebrospinal Fluid
94712-7	Movement disorder autoimmune Ab panel - Cerebrospinal Fluid
94353-0	Myelopathy autoimmune Ab panel - Cerebrospinal Fluid
94818-2	Paraneoplastic Ab panel - Cerebrospinal Fluid by Immunofluorescence

Language Variants Get Info

Tag	Language	Translation
cs-CZ	Czech (Czechia)	Antinukleární protilátky typu 3.IgG neuronální:Arbitrární koncentrace (titr):Časový bod:Mozkomíšní mok:Semikvantitativní:Imunofluoresecence (IF)
el-GR	Greek (Greece)	Νευρωνικός πυρηνικός τύπος 3 Αντισώματα IgG:Titr:Pt:ΕΝΥ:Ημιποσοτική:Ανοσοφθορισμός Synonyms: Pt SERO Titr Type Ανοσοσφαιρίνη G Ανοσοφθορισμός Αντίσωμα Αντισώματα IgG ΕΝΥ Ημιποσοτική Νευρωνικό Νευρωνικό πυρηνικό Νευρωνικός πυρηνικός τύπος 3 Πυρηνικό
es-ES	Spanish (Spain)	Neuronal nuclear tipo 3 IgG:Titulo / Factor de dilución:Punto temporal:Líquido Cefalorraquideo:Semicuantitativo:Inmunofluorescencia (IF) Synonyms: Semicuantitativo
es-MX	Spanish (Mexico)	Tipo nuclear neuronal 3 Ab.IgG:Título:Punto temporal:Fluído espinal cerebral:Cuantitativo:Inmunofluorescencia (IF)
fr-CA	French (Canada)	Neuronal nucléaire de type 3, IgG:Titre:Temps ponctuel:LCR:SemiQn:Immunofluorescence
fr-FR	French (France)	Neurone noyau type 3 Ac IgG:Titre:Ponctuel:Liquide céphalorachidien:Semi-Quantitatif:Immunofluorescence
it-IT	Italian (Italy)	Nucleare neuronale tipo 3 Ab.IgG:Titr:Pt:LCS:SemiQn:IF Synonyms: anticorpi IgG anticorpo Immunofluorescenza (IF) Liquido cerebrospinale Punto nel tempo (episodio) Sierologia (anticorpi e la maggior parte degli ant Titolo
nl-NL	Dutch (Netherlands)	neuronaal nucleair type 3 As.IgG:titer:moment:liquor cerebrospinalis:semikwantitatief:immunofluorescentie Synonyms: antistof; antilichaam IF soort
pl-PL	Polish (Poland)	Typ 3 neuronalny jądrowy Ab.IgG:miano:punkt w czasie:płyn mózgowo-rdzeniowy:półilościowy:immunofluorescencja Synonyms: IgG Przeciwciała do antygenów jądrowych neuronów typu 3 przeciwciała IgG Przeciwciała IgG do antygenów jądrowych neuronów typu 3 Przeciwciała onkoneuronalne
zh-CN	Chinese (China)	神经元细胞核 3 型抗体.IgG:滴定度:时间点:脑脊液:半定量型:免疫荧光法 Synonyms: Ⅲ Ab.IgG;IgG;抗体 IgG Ab;自身抗体 ANNA 3 Ab ANNA 3 抗体 ANNA 3;ANNA-3;Hu3;神经元核 3 型;神经元细胞核 3 型（Neuronal nuclear type 3，ANNA 3） ANNA-3 Ab ANNA-3 抗体 CSF CSF;脊髓液;Cerebral spinal fluid;脑脊髓液 FANA Hu3 Ab Hu3 抗体 IFA法;IF法;抗补体免疫荧光法;时间分辨荧光法;荧光原位杂交技术;荧光原位杂交法;荧光抗体 III 三免疫球蛋白 G 叁型效价;滴定浓度;滴定率;滴定量;滴度;稀释倍数;稀释因子;稀释系数时刻;随机;随意;瞬间核;胞核核心抗体IgG 核心抗原抗体.IgG 核心抗原抗体IgG 核心抗原抗体免疫荧光核抗体.IgG 核抗体IgG 核抗原抗体.IgG 核抗原抗体IgG 神经元性;神经元的神经元核神经元核 3 型 Ab 神经元核 3 型抗体神经元细胞核 3 型 Ab 脊液脊髓液脑脊液（Cerebral spinal fluid，CSF）脑脊髓液血清;血清学;血清学检验项目;血清学检验项目 (非微生物学);血清学检验项目（非微生物学）;血清学检验项目类;血清学检验项目类 (非微生物学);血清学类;血清学类检验项目;血清学类检验项目 (非微生物学);血清学类试验;血清学类试验 (非微生物学);血清学试验;血清学试验 (非微生物学);血清学试验（非微生物学）;血清学试验类 (非微生物学);血清类

Example Units

Unit	Source
{titer}	Example UCUM Units

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LOINC Copyright

Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.