94556-8
dRVVT excess phospholipid in Platelet poor plasma by Coagulation assay --post DOAC neutralization
Active
Term Description
Quantitative analysis of Dilute Russell Viper Venom (DRVVT) post neutralization (absorption) of direct oral anticoagulants (DOAC) using activated charcoal (DOAC remove®, DOAC stop™) or other methods
Source: Regenstrief LOINC
Part Descriptions
LP65493-6 Coagulation dilute Russell viper venom induced.excess phospholipid
Dilute Russell viper venom time (dRVVT) is a screening laboratory test for detecting the presence of lupus anticoagulants (LA), which are autoantibodies associated with excess clot formation, excess bleeding, and repeated miscarriages. The coagulant in the venom directly activates factor X, which turns prothrombin into thrombin in the presence of factor V and phospholipid. If phospholipid antibodies are present, this reaction will be inhibited, which will prolong the screening dRVVT and suggests the presence of LA. A confirmatory dRVVT test measures dRVVT in the presence of excess phospholipid, which saturates the antibody binding sites and thereby diminishes the inhibitory effect of the LA, resulting in a normalization of the dRVVT. The dRVVT screen to confirm ratio is calculated as Screen dRVVT/Confirm dRVVT, and the dRVVT percent correction is calculated as [(Screen dRVVT - Confirm dRVVT)/Screen dRVVT]x100. PMID: 19624461
Source: Regenstrief LOINC, PMID: 19624461
LP21280-0 Dilute Russell viper venom time
Dilute Russell's viper venom time (dRVVT) is a laboratory test for lupus anticoagulant (LA). This in vitro diagnostic test is based on the property that the venom of the Russell's Viper is effective at inducing thrombosis. The coagulant in the venom directly activates factor X, which turns prothrombin into thrombin in the presence of factor V and phospholipid. The venom is diluted to give a clotting time of 23 to 27 seconds and the phospholipid is reduced to make the test extremely sensitive to phospholipid. The dRVVT test is more sensitive than the aPTT test for the detection of lupus anticoagulant (an autoimmune disorder), because it is not influenced by deficiencies in clotting factors VIII, IX or XI. The dRVVT is thought to be more sensitive than the activated partial thromboplastin time (aPTT) for detection of lupus anticoagulants.
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Source: Wikipedia, Dilute Russell viper venom time (Wikipedia)
Fully-Specified Name
- Component
- Coagulation dilute Russell viper venom induced.excess phospholipid^post DOAC neutralization
- Property
- Time
- Time
- Pt
- System
- PPP
- Scale
- Qn
- Method
- Coag
Additional Names
- Short Name
- dRVVT confirm p DOAC neut PPP
- Display Name
- dRVVT excess phospholipid post DOAC neutralization Coag (PPP) [Time]
- Consumer Name Alpha Get Info
- dRVVT excess phospholipid post DOAC neutralization, Blood
Basic Attributes
- Class
- COAG
- Type
- Laboratory
- First Released
- Version 2.68
- Last Updated
- Version 2.68
- Order vs. Observation
- Observation
Language Variants Get Info
Tag | Language | Translation |
---|---|---|
es-ES | Spanish (Spain) | Coagulación inducida por el veneno de vibora de Russell diluido. Exceso de fosfolípido^Pos neutralización de DOAC: Synonyms: Cuantitativo |
es-MX | Spanish (Mexico) | Coagulación diluida por veneno de víbora de Russell inducida por exceso de fosfolípidos ^ después de la neutralización de DOAC: |
fr-FR | French (France) | Temps de venin vipère Russell dilué en excès de phospholipides après neutralisation au DOAC: |
it-IT | Italian (Italy) | Coagulazione indotta da veleno diluito di vipera Russell.fosfolipidi in eccesso^post DOAC, neutralizzazione: Synonyms: Plasma povero di piastrine post anticoagulanti orali diretti, neutralizzazione Punto nel tempo (episodio) Studio di coagulazione Tempo (e.g. secondi) Tempo di veleno diluito di vipera Russel (dRVVT) Tempo di veleno diluito di vipera Russel (dRVVT) f Test di coagulazione |
nl-NL | Dutch (Netherlands) | stolling, verdunde Russell viper venom-geïnduceerd.overmaat fosfolipide^na neutralisatie met direct werkende orale anticoagulans: Synonyms: coagulatiemethode na DOAC-neutralisatie stolling, verdunde Russell viper venom geinduceerd.overmaat fosfolipide |
zh-CN | Chinese (China) | 稀释蝰蛇毒诱导型凝血过程.过量磷脂^在直接口服抗凝剂中和之后: Synonyms: CRVV DDRVTVT dRVV dRVV 时间; |
Example Units
Unit | Source |
---|---|
s | Example UCUM Units |
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