Version 2.76

Term Description

The quantitative cross/cycle threshold (Ct) value for the detection of nucleic acids within the spike (S) gene of the SARS coronavirus 2 (SARS-CoV-2) in various respiratory specimens by PCR with probe-based detection.
Source: Regenstrief LOINC

Part Description

LP418046-1   SARS coronavirus 2 S gene
The Severe acute respiratory syndrome (SARS) coronavirus 2 (SARS-CoV-2), first known as 2019 Novel Coronavirus (2019-nCoV), was first identified as the cause of a respiratory illness outbreak, later defined as Coronavirus Disease 2019 (COVID-19), in Wuhan, China. The full genome of the SARS-CoV-2 that causes COVID-19 was first posted by Chinese health authorities in GenBank, the NIH genetic sequence database, and in the Global Initiative on Sharing All Influenza Data (GISAI) portal. This facilitated detection of the virus globally with subsequent sequences being nearly identical, suggesting a single, recent emergence from a virus related to bat coronaviruses and the SARS coronavirus. Real time Reverse Transcription-Polymerase Chain Reaction (rRT-PCR) tests targeting regions within genes, including RdRp, S, N, M, and E genes, specific to SARS-CoV-2 have been developed by the Centers for Disease Control and Prevention (CDC), the World Health Organization (WHO) and others for the diagnosis of COVID-19. Some assays only detect SARS-CoV-2 and other assays detect other strains (e.g. SARS-CoV) that are genetically similar.[CDC: coronavirus/2019-ncov][https://www.who.int/emergencies/diseases/novel-coronavirus-2019/technical-guidance/laboratory-guidance] Source: Regenstrief LOINC

Reference Information

Type Source Reference
Webcontent Lab Tests Online®Copyright Copyright © 2021 Lab Tests Online. All rights reserved. Coronavirus (COVID-19) Testing

Fully-Specified Name

Component
SARS coronavirus 2 S gene
Property
ThreshNum
Time
Pt
System
Respiratory System Specimen
Scale
Qn
Method
Probe.amp.tar

Additional Names

Short Name
SARS-CoV-2 S gene Ct Resp Qn NAA+probe
Display Name
SARS-CoV-2 (COVID-19) S gene NAA+probe (Respiratory system specimen) [ThreshNum]
Consumer Name Alpha Get Info
SARS-CoV-2 (COVID-19) S gene, Respiratory system specimen

Ask at Order Entry

81959-9 Public health laboratory ask at order entry panel

This panel contains a convenience grouping of terms for questions commonly asked when an order is placed in a public health laboratory.

LOINC Name R/O/C Cardinality Example UCUM Units
81959-9 Public health laboratory ask at order entry panel
Indent81744-5 Submitter's laboratory test method [Type] in Specimen
Indent81658-7 Suspected organism [Identifier] in Specimen
Indent86952-9 Preliminary testing done Specimen
Indent86953-7 Preliminary testing result Specimen
Indent86955-2 Preliminary testing affected submission for further testing Specimen
Indent95417-2 Whether this is the patient's first test for condition of interest
Indent95418-0 Whether patient is employed in a healthcare setting
Indent95419-8 Whether the patient has symptoms related to condition of interest
Indent11368-8 Illness or injury onset date and time C
Indent77974-4 Whether the patient was hospitalized for condition of interest
Indent95420-6 Whether the patient was admitted to intensive care unit (ICU) for condition of interest
Indent95421-4 Whether patient resides in a congregate care setting
Indent82810-3 Pregnancy status C
Indent30525-0 Age a

Basic Attributes

Class
MICRO
Type
Laboratory
First Released
Version 2.68
Last Updated
Version 2.75
Change Reason
Release 2.75: SYSTEM: There are 2 similar system's in LOINC: 1- Respiratory system 2- Respiratory specimen Due to an applied logic, the display in the System axis for 1 is Respiratory (adjective) without specification of sample, specimen, or other specific noun, while 2 is displayed fully as Respiratory specimen. Therefore for now we replaced 1 with Respiratory system specimen, which will affect 83 term. The result is replacing "Respiratory" with "Respiratory system specimen". This is the short approach. The bigger project is to potentially merge data that has either 1 or 2 together. This is a project to pass by the laboratory committee and will involve about 1500 concepts.;
Order vs. Observation
Observation

Member of these Panels

LOINC Long Common Name
96094-8 SARS-CoV-2 (COVID-19) and SARS-related CoV RNA panel - Respiratory system specimen by NAA with probe detection
94531-1 SARS-CoV-2 (COVID-19) RNA panel - Respiratory system specimen by NAA with probe detection

Member of these Groups Get Info

LOINC Group Group Name
LG51017-8 SARSCoV2 detection
LG51019-4 SARSCoV2 molecular detection

Language Variants Get Info

Tag Language Translation
de-DE German (Germany) SARS-Coronavirus 2 S-Gen:Ct-Wert:Zeitpunkt:Respirationstrakt:Quantitativ:Zielfragmentamplifikation mit Sondendetektion
es-ES Spanish (Spain) Gen S de SARS-CoV-2 (COVID-19):ThreshNnum:Punto temporal:Muestra del sistema respiratorio:Qn:Sonda con amplificación dirigida
Synonyms: Cuantitativo Muestra del tracto respiratorio Muestra respiratoria Tracto respiratorio
es-MX Spanish (Mexico) Gen del coronavirus 2 S del SARS:ThreshNum:Punto temporal:Espécimen respiratorio:Cuantitativo:Amplificación de ácidos nucleicos con detección de sonda
fr-FR French (France) Coronavirus SARS-CoV-2 gène S:Cycle seuil:Ponctuel:Spécimen du système respiratoire:Numérique:PCR amplification de cible
it-IT Italian (Italy) SARS-CoV-2 (COVID-19), gene S:Thresnum:Pt:Campione da Sistema Respiratorio:Qn:Sonda.amp.tar
Synonyms: Campione da Apparato Respiratorio Coronavirus della SARS Gene S di SARS-CoV-2 (COVID-19) Limite di soglia Microbiologia Punto nel tempo (episodio) SARS-CoV-2 (COVID-19) Sonda con amplificazione Sonda con amplificazione del target Sonda di DNA
nl-NL Dutch (Netherlands) SARS-CoV-2 S-gen:drempelwaarde nummer:moment:ademhalingsstelsel:kwantitatief:probe-detectie
Synonyms: probe.amp.tar SARS-virus severe acute respiratory syndrome coronavirus 2; 2019-nCoV; 2019 novel coronavirus; COVID-19 systema respiratorium; ademhalingsstelsel

Example Units

Unit Source
{Ct_value} Example UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=94642-6