94674-9

25-Hydroxyvitamin D3+25-Hydroxyvitamin D2/24,25-dihydroxyvitamin D3+24,25-dihydroxyvitamin D2 ratio panel in Serum or Plasma

Active

Term Description

Testing for an elevated ratio of 25HDN to 24,25 DHD can be used to reveal the likely presence of mutations in the CYP24A1 gene. CYP24A1 converts 25 hydroxyvitamin D to 24,25 dihydroxyvitamin D, a process thought to prevent overproduction of the active metabolite 1,25 dihydroxyvitamin D.

Part Descriptions

LP182450-9 Calcidiol+ercalcidiol
The total of 25-hydroxyvitamin D3 (calcidiol) + 25-hydroxyvitamin D2 (ercalcidiol), which is often reported simply as 25-hydroxyvitamin D, or 25-OH-D. Source: Regenstrief LOINC

LP417249-2 Calcidiol+ercalcidiol/24r-Hydroxycalcidiol+24r-Hydroxyercalcidiol ratio panel
24,25-dihydroxyvitamin D (24,25 DHD), also known as 24r-Hydroxycalcidiol, is an INactive metabolite produced by alternative hydroxylation of 25 hydroxyvitamin D (25HDN) by the CYP24A1 enzyme. The hydroxylation by CYP24A1 competes with hydroxylation to active form 1,25-dihydroxyvitamin D (1,25 DHD) by the CYP27B1 enzyme, and is an important process that prevents overproduction of 1,25 DHD and resulting vitamin D toxicity. Testing for an elevated ratio of 25HDN to 24,25 DHD can be used to reveal the likely presence of mutations in the CYP24A1 gene PMID: 22648296. Source: Regenstrief LOINC

Panel Hierarchy

Details for each LOINC in Panel LHC-Forms

LOINC	Name	R/O/C	Example UCUM Units
94674-9	25-Hydroxyvitamin D3+25-Hydroxyvitamin D2/24,25-dihydroxyvitamin D3+24,25-dihydroxyvitamin D2 ratio panel in Serum or Plasma
Indent94673-1	25-Hydroxyvitamin D3+25-Hydroxyvitamin D2/24,25-dihydroxyvitamin D3+24,25-dihydroxyvitamin D2 [Mass Ratio] in Serum or Plasma		{ratio}
Indent94672-3	24,25-dihydroxyvitamin D3+24,25-dihydroxyvitamin D2 [Mass/volume] in Serum or Plasma		ng/mL
Indent49590-3	Calcidiol and Calciferol panel - Serum or Plasma
IndentIndent62292-8	25-Hydroxyvitamin D3+25-Hydroxyvitamin D2 [Mass/volume] in Serum or Plasma	R	ng/mL
IndentIndent1989-3	25-hydroxyvitamin D3 [Mass/volume] in Serum or Plasma	R	ng/mL
IndentIndent49054-0	25-hydroxyvitamin D2 [Mass/volume] in Serum or Plasma	R	ng/mL
IndentIndent49591-1	Calcidiol and Calciferol [Interpretation] in Serum or Plasma Narrative	O

LOINC Names Get Info

Fully-Specified Name: Calcidiol+ercalcidiol/24r-Hydroxycalcidiol+24r-Hydroxyercalcidiol ratio panel:-:Pt:Ser/Plas:-:
Long Common Name: 25-Hydroxyvitamin D3+25-Hydroxyvitamin D2/24,25-dihydroxyvitamin D3+24,25-dihydroxyvitamin D2 ratio panel in Serum or Plasma
Short Name: 25D3+25D2/24,25D3+24,25D2 Pnl SerPl
Display Name: 25-hydroxyvitamin D/24,25-dihydroxyvitamin D3+24,25-dihydroxyvitamin D2 ratio panel
Consumer Name Alpha Get Info: 25-hydroxyvitamin D/24,25-dihydroxyvitamin D3+24,25-dihydroxyvitamin D2 ratio panel, Blood

Part Model Get Info

Component
Calcidiol+ercalcidiol/24r-Hydroxycalcidiol+24r-Hydroxyercalcidiol ratio panel
LP417249-2
- Analyte
  Calcidiol+ercalcidiol/24r-Hydroxycalcidiol+24r-Hydroxyercalcidiol ratio panel
  LP417249-2
  - Component Numerator
    Calcidiol+ercalcidiol
    LP182450-9
    - Component Numerator Core
      Calcidiol+ercalcidiol
      LP182450-9
    - Component Numerator Core Suffix
      NULL
  - Component Denominator
    24r-Hydroxycalcidiol+24r-Hydroxyercalcidiol ratio panel
    LP417742-6
    - Component Denominator Core
      24r-Hydroxycalcidiol+24r-Hydroxyercalcidiol ratio panel
      LP417742-6
    - Component Denominator Core Suffix
      NULL
- Challenge
  NULL
- Adjustment
  NULL
- Count
  NULL
Property
-
LP6769-6
Time
Pt
LP6960-1
- Time Core
  Pt
  LP6960-1
- Time Modifier
  NULL
System
Ser/Plas
LP7576-4
- System Core
  Ser/Plas
  LP7576-4
- Super System
  NULL
Scale
-
LP7747-1
Method
NULL

Basic Attributes

Class: PANEL.CHEM
Type: Laboratory
First Released: Version 2.68
Last Updated: Version 2.68 (ADD)
Order vs. Observation: Order
Panel Type: Panel

Language Variants Get Info

Tag	Language	Translation
cs-CZ	Czech (Czechia)	25-hydroxycholekalciferol+25-hydroxyergoekalciferol/24,25-dihydroxycholekalciferol+24,25-dihydroxyergoekalciferol poměr panel:-:Časový bod:Sérum/plazma:-:
el-GR	Greek (Greece)	Καλσιδιόλη+ερκαλσιδιόλη/Πίνακας λόγου 24r-υδροξυκαλσιδιόλης+24r-υδροξυερκαλσιδιόλης:-:Pt:Ορός/Πλάσμα:-: Synonyms: - 24r-υδροξυκαλσιδιόλη 24r-υδροξυκαλσιδιόλη+24r-υδροξυερκαλσιδιόλη CHEM PANEL.CHEM Pt Ερκαλσιδιόλη Καλσιδιόλη Καλσιδιόλη+ερκαλσιδιόλη Ορός Ορός/Πλάσμα Πίνακας λόγου 24r-υδροξυκαλσιδιόλης+24r-υδροξυερκαλσιδιόλης Πλάσμα Υδροξυκαλσιδιόλη
es-ES	Spanish (Spain)	25-Hidroxivitamina D2+25-Hidroxivitamina D3/Panel de proporción de 24,25-dihidroxivitamina D3 + 24,25-dihidroxivitamina D2:Propiedades mixtas (sólo paneles):Punto temporal:Suero o Plasma:-:
es-MX	Spanish (Mexico)	Panel de relación calcidiol + ercalcidiol / 24r-Hydroxycalcidiol + 24r-Hydroxyercalcidiol:-:Punto temporal:Suero o Plasma:-:
fr-FR	French (France)	25-hydroxycholécalciférol+25-hydroxyergocalciférol/24r-hydroxycholécalciférol+24r-hydroxyergocalciférol ratio panel:-:Ponctuel:Sérum/Plasma:-:
it-IT	Italian (Italy)	25-Idrossivitamina D2+25-Idrossivitamina D3/24r-Idrossicalcidiolo+24r-Idrossicalcidiolo, panel rapporto:-:Pt:Siero/Plasma:-: Synonyms: Chimica Panel rapporto 24,25-Diidrossivitamina D3+24,25-diidrossivitamina D2 Plasma Punto nel tempo (episodio) Set di prescrizione chimica Siero Siero o Plasma
nl-NL	Dutch (Netherlands)	25-hydroxyvitamine D2 + 25-hydroxyvitamine D3/24,25-dihydroxyvitamine D3 + 24,25-dihydroxyvitamine D2 verhouding panel:-:moment:serum of plasma:-: Synonyms: calcidiol + ercalcidiol; vitamine D2 + D3 calcidiol; vitamine D3 ercalcidiol; 25-hydroxycalciferol vitamine D3 + D2
pl-PL	Polish (Poland)	Kalcydiol+Erkalcydiol/panel 24r-hydroksykalcydiol+24r-hydroksyerkalcydiol stosunek:-:punkt w czasie:surowica lub osocze:-: Synonyms: 24,25-dihydroksywitamina D3 24,25-dihydroksywitamina D3 i 24,25-dihydroksywitamina D2 25-hydroksycholekalcyferol i 25-hydroksyergokalcyferol 25-hydroksycholekalcyferol;25 OH-D 25-hydroksyergokalcyferol
zh-CN	Chinese (China)	钙二醇+羟基钙二醇/24r-羟基钙二醇+24r,25-羟基钙化醇比率组套:-:时间点:血清/血浆:-: Synonyms: 24(R),25-二羟基维生素 D;24(R),25-二羟基胆维丁;24(R),25-二羟基胆钙化甾醇;24(R),25-二羟基胆钙化醇;24(R),25-二羟基胆骨化醇;24,25-二羟基维生素 D;24,25-二羟基胆维丁;24,25-二羟基胆钙化甾醇;24,25-二羟基胆钙化醇;24,25-二羟基胆骨化醇;24R-OH-钙二醇;维生素 D3 24r-羟基钙二醇+24r,25-羟基钙化醇比率组套（组合、医嘱组、套餐、套餐医嘱、医嘱套餐、组合申请、组合项目） 25-OH-维生素 D3;25OH-维生素 D3;25-羟基维生素 D;25-羟基维生素 D3;25-羟基胆维丁;25-羟基胆钙化醇;25-羟基胆骨化醇;25-羟维生素 D;25-羟维生素 D3;25-羟胆维丁;25-羟胆钙化醇;25-羟胆骨化醇;Calciderol;维生素 D 25 羟;维生素 D 25 羟基;骨化二醇 25-羟基钙化醇;25-羟基维生素 D2;25-羟基麦角钙化甾醇;25-羟基麦角钙化醇;25-羟基麦角骨化醇;9,10-断麦角甾-5,7,10(19),22-四烯-3 Beta,25-二醇;9,10-断麦角甾-5,7,10(19),22-四烯-3 β,25-二醇;Ercalcidiol;OH-Vit D2 25-羟维生素 D2+25-羟维生素 D3;25-羟基维生素 D2+25-羟基维生素 D3 OH-钙二醇化学;化学检验项目;化学检验项目类;化学类;化学试验;非刺激耐受型化学检验项目;非刺激耐受型化学检验项目类;非刺激耐受型化学试验;非刺激耐受型化学试验类医嘱套餐医嘱套餐类医嘱套餐组医嘱组医嘱组.化学试验;化学组套（组合、医嘱组、套餐、套餐医嘱、医嘱套餐、组合申请、组合项目）;化学医嘱组类;医嘱组.化学;医嘱组.化学检验项目;医嘱组类.化学;医嘱组类.化学检验项目;医嘱组类.化学试验;实验室医嘱组类.化学;实验室医嘱组类.化学检验项目;实验室医嘱组类.化学试验医嘱组合医嘱组合类医嘱组套医嘱组套类医嘱组类多重;多重型;多重标尺类型;多重精度类型套餐套餐医嘱套餐医嘱组套餐医嘱组类实验室医嘱套餐实验室医嘱套餐类实验室医嘱组实验室医嘱组合类实验室医嘱组套实验室医嘱组套类实验室套餐医嘱组实验室套餐医嘱组类实验室检验项目医嘱组合类实验室检验项目组合类时刻;随机;随意;瞬间检验医嘱组合类检验项目医嘱组合类检验项目组合类组组合组合医嘱组合类组套血清或血浆

LOINC Terminology Service (API) using HL7^® FHIR^® Get Info

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LOINC Copyright

Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.