Version 2.78

Term Description

Testing for an elevated ratio of 25HDN to 24,25 DHD can be used to reveal the likely presence of mutations in the CYP24A1 gene. CYP24A1 converts 25 hydroxyvitamin D to 24,25 dihydroxyvitamin D, a process thought to prevent overproduction of the active metabolite 1,25 dihydroxyvitamin D.
Source: Regenstrief LOINC

Part Descriptions

LP182450-9   Calcidiol+ercalcidiol
The total of 25-hydroxyvitamin D3 (calcidiol) + 25-hydroxyvitamin D2 (ercalcidiol), which is often reported simply as 25-hydroxyvitamin D, or 25-OH-D. Source: Regenstrief LOINC

LP417249-2   Calcidiol+ercalcidiol/24r-Hydroxycalcidiol+24r-Hydroxyercalcidiol ratio panel
24,25-dihydroxyvitamin D (24,25 DHD), also known as 24r-Hydroxycalcidiol, is an INactive metabolite produced by alternative hydroxylation of 25 hydroxyvitamin D (25HDN) by the CYP24A1 enzyme. The hydroxylation by CYP24A1 competes with hydroxylation to active form 1,25-dihydroxyvitamin D (1,25 DHD) by the CYP27B1 enzyme, and is an important process that prevents overproduction of 1,25 DHD and resulting vitamin D toxicity. Testing for an elevated ratio of 25HDN to 24,25 DHD can be used to reveal the likely presence of mutations in the CYP24A1 gene PMID: 22648296. Source: Regenstrief LOINC

Panel Hierarchy

Details for each LOINC in Panel LHC-Forms

LOINC Name R/O/C Cardinality Example UCUM Units
94674-9 25-Hydroxyvitamin D3+25-Hydroxyvitamin D2/24,25-dihydroxyvitamin D3+24,25-dihydroxyvitamin D2 ratio panel in Serum or Plasma
Indent94673-1 25-Hydroxyvitamin D3+25-Hydroxyvitamin D2/24,25-dihydroxyvitamin D3+24,25-dihydroxyvitamin D2 [Mass Ratio] in Serum or Plasma {ratio}
Indent94672-3 24,25-dihydroxyvitamin D3+24,25-dihydroxyvitamin D2 [Mass/volume] in Serum or Plasma ng/mL
Indent49590-3 Calcidiol and Calciferol panel - Serum or Plasma
IndentIndent62292-8 25-Hydroxyvitamin D3+25-Hydroxyvitamin D2 [Mass/volume] in Serum or Plasma R ng/mL
IndentIndent1989-3 25-hydroxyvitamin D3 [Mass/volume] in Serum or Plasma R ng/mL
IndentIndent49054-0 25-hydroxyvitamin D2 [Mass/volume] in Serum or Plasma R ng/mL
IndentIndent49591-1 Calcidiol and Calciferol [Interpretation] in Serum or Plasma Narrative O

Fully-Specified Name

Component
Calcidiol+ercalcidiol/24r-Hydroxycalcidiol+24r-Hydroxyercalcidiol ratio panel
Property
-
Time
Pt
System
Ser/Plas
Scale
-
Method

Additional Names

Short Name
25D3+25D2/24,25D3+24,25D2 Pnl SerPl
Display Name
25-hydroxyvitamin D/24,25-dihydroxyvitamin D3+24,25-dihydroxyvitamin D2 ratio panel
Consumer Name Alpha Get Info
25-hydroxyvitamin D/24,25-dihydroxyvitamin D3+24,25-dihydroxyvitamin D2 ratio panel, Blood

Basic Attributes

Class
PANEL.CHEM
Type
Laboratory
First Released
Version 2.68
Last Updated
Version 2.68
Order vs. Observation
Order
Panel Type
Panel

Language Variants Get Info

Tag Language Translation
es-ES Spanish (Spain) 25-Hidroxivitamina D2+25-Hidroxivitamina D3/Panel de proporción de 24,25-dihidroxivitamina D3 + 24,25-dihidroxivitamina D2:Propiedades mixtas (sólo paneles):Punto temporal:Suero o Plasma:-:
es-MX Spanish (Mexico) Panel de relación calcidiol + ercalcidiol / 24r-Hydroxycalcidiol + 24r-Hydroxyercalcidiol:-:Punto temporal:Suero o Plasma:-:
fr-FR French (France) 25-hydroxycholécalciférol+25-hydroxyergocalciférol/24r-hydroxycholécalciférol+24r-hydroxyergocalciférol panel:-:Ponctuel:Sérum/Plasma:-:
it-IT Italian (Italy) 25-Idrossivitamina D2+25-Idrossivitamina D3/24r-Idrossicalcidiolo+24r-Idrossicalcidiolo, panel rapporto:-:Pt:Siero/Plasma:-:
Synonyms: 24,25-Diidrossivitamina D3+24,25-diidrossivitamina D2 Chimica Panel rapporto 24,25-Diidrossivitamina D3+24,25-diidrossivitamina D2 Plasma Punto nel tempo (episodio) Set di prescrizione chimica Siero Siero o Plasma
nl-NL Dutch (Netherlands) 25-hydroxyvitamine D2 + 25-hydroxyvitamine D3/24,25-dihydroxyvitamine D3 + 24,25-dihydroxyvitamine D2 verhouding panel:-:moment:serum of plasma:-:
Synonyms: calcidiol + ercalcidiol; vitamine D2 + D3 calcidiol; vitamine D3 ercalcidiol; 25-hydroxycalciferol vitamine D3 + D2
zh-CN Chinese (China) 钙二醇+羟基钙二醇/24r-羟基钙二醇+24r,25-羟基钙化醇比率组套:-:时间点:血清/血浆:-:
Synonyms: 24(R),25-二羟基维生素 D;24(R),25-二羟基胆维丁;24(R),25-二羟基胆钙化甾醇;24(R),25-二羟基胆钙化醇;24(R),25-二羟基胆骨化醇;24,25-二羟基维生素 D;24,25-二羟基胆维丁;24,25-二羟基胆钙化甾醇;24,25-二羟基胆钙化醇;24,25-二羟基胆骨化醇;24R-OH-钙二醇;维生素 D3 24r-羟基钙二醇+24r,25-羟基钙化醇比率组套（组合、医嘱组、套餐、套餐医嘱、医嘱套餐、组合申请、组合项目） 25-OH-维生素 D3;25OH-维生素 D3;25-羟基维生素 D;25-羟基维生素 D3;25-羟基胆维丁;25-羟基胆钙化醇;25-羟基胆骨化醇;25-羟维生素 D;25-羟维生素 D3;25-羟胆维丁;25-羟胆钙化醇;25-羟胆骨化醇;Calciderol;维生素 D 25 羟;维生素 D 25 羟基;骨化二醇 25-羟基钙化醇;25-羟基维生素 D2;25-羟基麦角钙化甾醇;25-羟基麦角钙化醇;25-羟基麦角骨化醇;9,10-断麦角甾-5,7,10(19),22-四烯-3 Beta,25-二醇;9,10-断麦角甾-5,7,10(19),22-四烯-3 β,25-二醇;Ercalcidiol;OH-Vit D2 25-羟维生素 D2+25-羟维生素 D3;25-羟基维生素 D2+25-羟基维生素 D3 OH-钙二醇 化学;化学检验项目;化学检验项目类;化学类;化学试验;非刺激耐受型化学检验项目;非刺激耐受型化学检验项目类;非刺激耐受型化学试验;非刺激耐受型化学试验类 医嘱套餐 医嘱套餐类 医嘱套餐组 医嘱组 医嘱组.化学试验;化学组套（组合、医嘱组、套餐、套餐医嘱、医嘱套餐、组合申请、组合项目）;化学医嘱组类;医嘱组.化学;医嘱组.化学检验项目;医嘱组类.化学;医嘱组类.化学检验项目;医嘱组类.化学试验;实验室医嘱组类.化学;实验室医嘱组类.化学检验项目;实验室医嘱组类.化学试验 医嘱组合 医嘱组合类 医嘱组套 医嘱组套类 医嘱组类 多重;多重型;多重标尺类型;多重精度类型 套餐 套餐医嘱 套餐医嘱组 套餐医嘱组类 实验室医嘱套餐 实验室医嘱套餐类 实验室医嘱组 实验室医嘱组合类 实验室医嘱组套 实验室医嘱组套类 实验室套餐医嘱组 实验室套餐医嘱组类 实验室检验项目医嘱组合类 实验室检验项目组合类 时刻;随机;随意;瞬间 检验医嘱组合类 检验项目医嘱组合类 检验项目组合类 组 组合 组合医嘱 组合类 组套 血清或血浆

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=94674-9
Questionnaire definition
https://fhir.loinc.org/Questionnaire/?url=http://loinc.org/q/94674-9