Version 2.78

Part Descriptions

LP15629-6   Heparan sulfate
Heparan sulfate is a derived disaccharide that accumulates in lysosomes, extracellular matrix, and body fluids of people with mucopolysaccharidoses (MPSs). MPSs are rare disorders caused by a deficiency of enzymes that break down glycosaminoglycans (GAGs). Symptoms of MPS vary due to which storage product accumulates and the level of enzymatic function or concentration that remains. Symptoms include musculoskeletal, airway, cardiac, and central nervous system disorders. Treatments include hematopoietic stem cell transplantation for the more critical forms of MPS and intravenous enzyme replacement therapy for the others. Treatment is most effective when it is initiated before irreversible tissue damage has occurred. Because MPS is so rare and the symptoms so variable, it is difficult to diagnose in its earliest stages. A solution to that problem is the development of newborn screening assays that can detect heparan sulfate, though the levels in the dried blood spot samples do not appear to predict the severity of disease. The pattern of dermatan and heparan sulfate can help distinguish between the different MPSs. PMID: 23084433 Source: Regenstrief LOINC

LP32035-5   Creatinine
Creatinine or creatine anhydride, is a breakdown product of creatine phosphate in muscle. The loss of water molecule from creatine results in the formation of creatinine. It is transferred to the kidneys by blood plasma, whereupon it is eliminated by glomular filtration and partial tubular excretion. Creatinine is usually produced at a fairly constant rate and measuring its serum level is a simple test. A rise in blood creatinine levels is observed only with marked damage to functioning nephrons; therefore this test is not suitable for detecting early kidney disease. Creatine and creatinine are metabolized in the kidneys, muscle, liver and pancreas. Copyright Copyright ©2005-2009 Genome Alberta (Reference to original publication: Wishart DS, Knox C, Guo AC, et al. HMDB: a knowledgebase for the human metabolome. Nucleic Acids Res. 2009 37(Database issue):D603-610.) Source: Human Metabolome Database, Creatinine

Fully-Specified Name

Component
Heparan sulfate/Creatinine
Property
Ratio
Time
Pt
System
Urine
Scale
Qn
Method

Additional Names

Short Name
Heparan sulfate/Creat Ur-Rto
Display Name
Heparan sulfate/Creatinine (U) [Ratio]
Consumer Name Alpha Get Info
Heparan sulfate/Creatinine, Urine

Basic Attributes

Class
CHEM
Type
Laboratory
First Released
Version 2.68
Last Updated
Version 2.73
Order vs. Observation
Observation
Common Test Rank Get Info
11724

Member of these Panels

LOINC Long Common Name
94691-3 Dermatan sulfate, heparan sulfate, chondroitin-6-sulfate, keratan sulfate panel - Urine
105125-9 Lysosomal storage disorders screen panel - Urine

Language Variants Get Info

Tag Language Translation
es-ES Spanish (Spain) Heparán sulfato/Creatinina:Fracción:Punto temporal:Orina:Qn:
Synonyms: Cuantitativo
es-MX Spanish (Mexico) Sulfato de Heparán / Creatinina:Proporción:Punto temporal:Orina:Cuantitativo:
et-EE Estonian (Estonia) Heparaansulfaat/kreatiniin:Suhe:Pt:U:Qn:
Synonyms: Juhuslik Kvantitatiivne Uriin
fr-CA French (Canada) Héparane-sulfate/Créatinine:Ratios:Temps ponctuel:Urine:Quantitatif:
fr-FR French (France) Héparane sulfate/créatinine:Ratio:Ponctuel:Urine:Numérique:
fr-BE French (Belgium) Héparane-sulfate/Créatinine:Ratios:Temps ponctuel:Urine:Quantitatif:
Synonyms: SO4
it-IT Italian (Italy) Eparan solfato/Creatinina:Rapporto:Pt:Urine:Qn:
Synonyms: Chimica Punto nel tempo (episodio)
nl-NL Dutch (Netherlands) heparansulfaat/creatinine:verhouding:moment:urine:kwantitatief:
Synonyms: kreatinine
ru-RU Russian (Russian Federation) Гепаран сульфат/Креатинин:Отношение:ТчкВрм:Моча:Колич:
Synonyms: Гепарансульфат Количественный Коэффициент;Соотношение;Пропорция Точка во времени;Момент
tr-TR Turkish (Turkey) Heparan sülfat/Kreatinin:Oran:Zmlı:İdrar:Kant:
zh-CN Chinese (China) 硫酸类肝素/肌酐:比率:时间点:尿液:定量型:
Synonyms: CR;Creat;肌氨酸酐;肌酸内酰胺;肌酸酐 SO4;SO4-2;Sulf;硫酸;硫酸根;硫酸盐;硫酸酯 UCr 化学;化学检验项目;化学检验项目类;化学类;化学试验;非刺激耐受型化学检验项目;非刺激耐受型化学检验项目类;非刺激耐受型化学试验;非刺激耐受型化学试验类 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 尿;小便;下泉 尿液肌酐 尿液肌酸酐 尿肌酸酐 时刻;随机;随意;瞬间 来自于不同体系的两个观察指标之比;比;比值 硫酸乙酰型肝素;硫酸乙酰肝素;硫酸肝素 肌酸内酰胺

Example Units

Unit Source
mg/mmol{creat} Example UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=94693-9