94822-4
SARS-CoV-2 (COVID-19) RNA [Presence] in Saliva (oral fluid) by Sequencing
Active
Term Description
Qualitative detection of nucleic acid from the SARS coronavirus 2 (SARS-CoV-2) in saliva by sequencing methods, such as next generation sequencing (NGS), also known as high-throughput sequencing (HTS). Testing is performed for the diagnosis of COVID-19.
Source: Regenstrief LOINC
Part Descriptions
LP150045-5 Sequencing
Sequencing is a method used to determine the sequence of individual genes, larger genetic regions (i.e. clusters of genes or operons), full chromosomes or entire genomes. Historically, most sequencing has been performed using the chain termination method developed by Frederick Sanger in 1977. PMID: 271968 Sequencing technologies have improved dramatically, making them cheaper, faster, and more accurate. Next-generation sequencing (NGS), also known as high-throughput sequencing, deep sequencing, and second-generation sequencing, is a type of technology that uses parallel sequencing of multiple small fragments of DNA to determine sequence. This "high-throughput" technology has increased the speed and amount of DNA sequenced at a significantly reduced cost. PMID: 18576944 Several NGS platforms (ie, sequencing instruments and associated reagents) have been developed. Third-generation sequencing is another methodology currently under development that uses parallel sequencing similar to NGS. In contrast to NGS, third-generation sequencing uses single DNA molecules rather than amplified DNA as a template. PMID: 20858600
Source: Regenstrief LOINC
LP417540-4 SARS coronavirus 2
The 2019 Novel Coronavirus (2019-nCoV) is a coronavirus first identified as the cause of a respiratory illness outbreak in Wuhan, China. Initially, the outbreak was linked to a large seafood and animal market and thought to only be spread by animal to person contact. Within a short time, a growing number of patients who had not been exposed to animal markets were diagnosed with the infection, indicating person-to-person transmission. As of January 2020, infections with 2019-nCoV had been reported internationally due to confirmed cases in travelers from Wuhan. Overall, clinical symptoms appear milder than SARS Coronavirus (SARS-CoV) and Middle East Respiratory Syndrome (MERS) Coronavirus (MERS-CoV) infections as do the fatality rate and transmissibility. PMID: 31953166 Reported illnesses range from minor or no respiratory symptoms to severe acute respiratory illness and death.
The full genome of the 2019-nCoV was first posted by Chinese health authorities in GenBank, the NIH genetic sequence database, and in the Global Initiative on Sharing All Influenza Data (GISAI) portal. This facilitated detection of the virus globally with subsequent sequences being nearly identical, suggesting a single, recent emergence from a virus related to bat coronaviruses and the SARS coronavirus.
Source: LOINC
LP7565-7 Saliva
Saliva is produced primarily by the parotid, submaxillary, and sublingual glands. It is secreted at the rate of 0-3 milliliters per minute which is affected by various factors including anxiety, hydration and hunger. Oral fluid is broadly used to test for drugs of abuse in employment and forensic settings, and is especially useful since it is difficult to adulterate, is quick and is non-invasive. Oral fluid is used to test a variety of analytes, including to test alcohol, HIV and other antibodies, therapeutic drugs and steroids, but its primary use is to test for drugs of abuse including amphetamines, cocaine and metabolites, opioids, methadone, cannabis and heroin. PMID: 17268583
Source: Regenstrief LOINC
Reference Information
| Type | Source | Reference |
|---|---|---|
| Webcontent | Lab Tests Online®Copyright Copyright © 2021 Lab Tests Online. All rights reserved. | Coronavirus (COVID-19) Testing |
Fully-Specified Name
- Component
- SARS coronavirus 2 RNA
- Property
- PrThr
- Time
- Pt
- System
- Saliva
- Scale
- Ord
- Method
- Sequencing
Additional Names
- Short Name
- SARS-CoV-2 RNA Sal Ql Seq
- Display Name
- SARS-CoV-2 (COVID-19) RNA Sequencing Ql (Sal)
- Consumer Name Alpha Get Info
- SARS-CoV-2 (COVID-19), Saliva
Ask at Order Entry
81959-9 Public health laboratory ask at order entry panel
This panel contains a convenience grouping of terms for questions commonly asked when an order is placed in a public health laboratory.
| LOINC | Name | R/O/C | Cardinality | Example UCUM Units |
|---|---|---|---|---|
| 81959-9 | Public health laboratory ask at order entry panel | |||
| Indent81744-5 | Submitter's laboratory test method [Type] in Specimen | |||
| Indent81658-7 | Suspected organism [Identifier] in Specimen | |||
| Indent86952-9 | Preliminary testing done Specimen | |||
| Indent86953-7 | Preliminary testing result Specimen | |||
| Indent86955-2 | Preliminary testing affected submission for further testing Specimen | |||
| Indent95417-2 | Whether this is the patient's first test for condition of interest | |||
| Indent95418-0 | Whether patient is employed in a healthcare setting | |||
| Indent95419-8 | Whether the patient has symptoms related to condition of interest | |||
| Indent11368-8 | Illness or injury onset date and time | C | ||
| Indent77974-4 | Whether the patient was hospitalized for condition of interest | |||
| Indent95420-6 | Whether the patient was admitted to intensive care unit (ICU) for condition of interest | |||
| Indent95421-4 | Whether patient resides in a congregate care setting | |||
| Indent82810-3 | Pregnancy status | C | ||
| Indent30525-0 | Age | a |
Example Answer List: LL2021-5
Source: Gen-Probe| Answer | Code | Score | Answer ID |
|---|---|---|---|
| PositiveCopyright http://snomed.info/sct ID:10828004 Positive (qualifier value) | LA6576-8 | ||
| NegativeCopyright http://snomed.info/sct ID:260385009 Negative (qualifier value) | LA6577-6 | ||
| InvalidCopyright http://snomed.info/sct ID:455371000124106 Invalid result (qualifier value) | LA15841-2 |
Basic Attributes
- Class
- MICRO
- Type
- Laboratory
- First Released
- Version 2.68
- Last Updated
- Version 2.69
- Order vs. Observation
- Both
Member of these Groups Get Info
| LOINC Group | Group Name |
|---|---|
| LG51017-8 | SARSCoV2 detection |
| LG51019-4 | SARSCoV2 molecular detection |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| de-DE | German (Germany) | SARS-Coronavirus 2 RNA: |
| es-ES | Spanish (Spain) | Panel del SARS-CoV-2 (COVID-19) RNA: |
| es-MX | Spanish (Mexico) | ARN del coronavirus 2 del SARS: |
| fr-FR | French (France) | Coronavirus SARS-CoV-2 ARN: |
| fr-CA | French (Canada) | coronavirus 2 du SRAS ARN: |
| it-IT | Italian (Italy) | SARS coronavirus 2 RNA: Synonyms: Coronavirus della SARS Microbiologia Presenza o Soglia Punto nel tempo (episodio) SARS-CoV-2 (COVID-19) |
| nl-NL | Dutch (Netherlands) | SARS-CoV-2 RNA: Synonyms: SARS-virus severe acute respiratory syndrome coronavirus 2; |
| pl-PL | Polish (Poland) | SARS-CoV-2 RNA: Synonyms: Koronawirus |
| zh-CN | Chinese (China) | SARS 冠状病毒 2 RNA: Synonyms: 2019 新型冠状病毒; |
LOINC Terminology Service (API) using HL7® FHIR® Get Info
Requests to this service require a free LOINC username and password. Below is a sample of the possible capabilities. See the LOINC Terminology Service documentation for more information.
- CodeSystem lookup
- https:
//fhir.loinc.org/CodeSystem/$lookup?system=http: //loinc.org&code=94822-4
Third Party Copyright
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LOINC Copyright
Copyright © 2024 Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright