Version 2.80

94860-4 Transthyretin [Mass] in Blood

Part Descriptions

LP418389-5   Transthyretin
Transthyretin (TTR) (originally called prealbumin or thyroxine-binding prealbumin) is a homotetrameric unglycosylated tryptophan rich protein that carries the thyroid hormones T3 and T4, and retinol in serum and CSF. Synthesized in hepatocytes, TTR and has a molar mass of 55000 daltons. At a pH of 8.6, an electrophoretic band appears prior to albumin in a relative amount of < 2.5 % due to its greater rate of diffusion to the anode. Its function is to bind and transport low molecular weight retinol-binding proteins, preventing their glomerular filtration. 30 50 % of circulating TTR is complexed by retinol-binding protein. Additionally, it binds and transports thyroxine (T4), nevertheless its affinity to this hormone is less than that of thyroxine binding globulin. TTR is decreased in hepatocellular synthesis caused by acute liver damage, or dietary protein deficiency, and because of its short half life (approximately 2 days) is used as a surrogate marker of nutritional status. TTR is also a negative acute phase reactive protein and levels decrease in inflammatory states. Levels can be elevated in chronic renal failure, high concentrations of corticosteroids, and Hodgkin's disease. TTR misfolding and aggregation is known to be associated with the amyloid diseases, senile systemic amyloidosis (SSA), familial amyloid polyneuropathy (FAP), and familial amyloid cardiomyopathy (FAC) [Tietz] Source: Regenstrief LOINC , Wikipedia: Transthyretin

Fully-Specified Name

Component
Transthyretin
Property
Mass
Time
Pt
System
Bld
Scale
Qn
Method

Basic Attributes

Class
CHEM
Type
Laboratory
First Released
Version 2.68
Last Updated
Version 2.68 (ADD)
Order vs. Observation
Observation

Member of these Panels

LOINC Long Common Name
94864-6 Transthyretin-associated familial amyloidosis panel - Blood

Language Variants Get Info

Tag Language Translation
el-GR Greek (Greece) Τρανσθυρετίνη:Mass:Pt:Αίμα:Qn:
Synonyms: Mass Τρανσθυρετίνη
es-ES Spanish (Spain) Transtiretina:Masa:Punto temporal:Sangre:Qn:
Synonyms: Cuantitativo
es-MX Spanish (Mexico) Transtiretina:Masa:Punto temporal:Sangre:Cuantitativo:
fr-FR French (France) Transthyrétine:Masse:Ponctuel:Sang:Numérique:
it-IT Italian (Italy) Transtiretina:Massa:Pt:Sangue:Qn:
Synonyms: Chimica Punto nel tempo (episodio) Sangue
nl-NL Dutch (Netherlands) transthyretine:massa:moment:bloed:kwantitatief:
zh-CN Chinese (China) 甲状腺素视黄质运载蛋白:质量:时间点:全血:定量型:
Synonyms: TTR; 甲状腺素结合前清蛋白;thyroxine binding prealbumin;TBPA;转甲状腺素蛋白;甲状腺素运载蛋白;甲状腺素运送蛋白 化学;化学检验项目;化学检验项目类;化学类;化学试验;非刺激耐受型化学检验项目;非刺激耐受型化学检验项目类;非刺激耐受型化学试验;非刺激耐受型化学试验类 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 时刻;随机;随意;瞬间 血;血液 重量

Example Units

Unit Source
u Example UCUM Units

94862-0 Transthyretin peak 2 [Mass] in Blood

Part Descriptions

LP418390-3   Transthyretin peak 2
Mass spectrometry of transthyretin typically results in one peak. However, patients with transthyretin-associated familial amyloidosis have two transthyretin peaks with different masses due to a structural change in the protein that causes it to be unstable. Source: Regenstrief LOINC

Fully-Specified Name

Component
Transthyretin peak 2
Property
Mass
Time
Pt
System
Bld
Scale
Qn
Method

Basic Attributes

Class
CHEM
Type
Laboratory
First Released
Version 2.68
Last Updated
Version 2.68 (ADD)
Order vs. Observation
Observation

Member of these Panels

LOINC Long Common Name
94864-6 Transthyretin-associated familial amyloidosis panel - Blood

Language Variants Get Info

Tag Language Translation
el-GR Greek (Greece) Μέγιστη τρανσθυρετίνη 2:Mass:Pt:Αίμα:Qn:
Synonyms: Mass Μέγιστη τρανσθυρετίνη 2 Τρανσθυρετίνη
es-MX Spanish (Mexico) Pico de transtiretina 2:Masa:Punto temporal:Sangre:Cuantitativo:
es-ES Spanish (Spain) Pico 2 de trasntiretina:Masa:Punto temporal:Sangre:Qn:
Synonyms: Cuantitativo
fr-FR French (France) Transthyrétine pic 2:Masse:Ponctuel:Sang:Numérique:
it-IT Italian (Italy) Transtiretina, picco 2:Massa:Pt:Sangue:Qn:
Synonyms: Chimica Punto nel tempo (episodio) Sangue
nl-NL Dutch (Netherlands) transthyretinepiek 2:massa:moment:bloed:kwantitatief:
zh-CN Chinese (China) 甲状腺素视黄质运载蛋白峰值 2:质量:时间点:全血:定量型:
Synonyms: Ⅱ II TTR; 甲状腺素结合前清蛋白;thyroxine binding prealbumin;TBPA;转甲状腺素蛋白;甲状腺素运载蛋白;甲状腺素运送蛋白 化学;化学检验项目;化学检验项目类;化学类;化学试验;非刺激耐受型化学检验项目;非刺激耐受型化学检验项目类;非刺激耐受型化学试验;非刺激耐受型化学试验类 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 时刻;随机;随意;瞬间 甲状腺素视黄质运载蛋白（TTR、甲状腺素结合前清蛋白、TBPA、转甲状腺素蛋白、甲状腺素运载蛋白、甲状腺素运送蛋白）峰值 2 血;血液 重量

Example Units

Unit Source
u Example UCUM Units

94861-2 Transthyretin - transthyretin peak 2 [Mass difference] in Blood

Fully-Specified Name

Component
Transthyretin - transthyretin peak 2
Property
MDiff
Time
Pt
System
Bld
Scale
Qn
Method

Basic Attributes

Class
CHEM
Type
Laboratory
First Released
Version 2.68
Last Updated
Version 2.68 (ADD)
Order vs. Observation
Observation

Member of these Panels

LOINC Long Common Name
94864-6 Transthyretin-associated familial amyloidosis panel - Blood

Language Variants Get Info

Tag Language Translation
el-GR Greek (Greece) Τρανσθυρετίνη - Μέγιστη τρανσθυρετίνη 2:MDiff:Pt:Αίμα:Qn:
Synonyms: MDiff Μέγιστη τρανσθυρετίνη 2 Τρανσθυρετίνη Τρανσθυρετίνη - Μέγιστη τρανσθυρετίνη 2
es-MX Spanish (Mexico) Transtiretina - pico 2 de transtiretina:Diferencia de masa:Punto temporal:Sangre:Cuantitativo:
es-ES Spanish (Spain) Transtiretina-pico 2 de trasntiretina:Diferencia de masa:Punto temporal:Sangre:Qn:
Synonyms: Cuantitativo
fr-FR French (France) Transthyrétine - Transthyrétine pic 2:Masse différence:Ponctuel:Sang:Numérique:
it-IT Italian (Italy) Transtiretina - Transtiretina, picco 2:Differenza massa:Pt:Sangue:Qn:
Synonyms: Chimica Punto nel tempo (episodio) Sangue
nl-NL Dutch (Netherlands) transthyretine - transthyretinepiek 2:massaverschil:moment:bloed:kwantitatief:
zh-CN Chinese (China) 甲状腺素视黄质运载蛋白 - 甲状腺素视黄质运载蛋白峰值 2:质量差:时间点:全血:定量型:
Synonyms: Ⅱ II TTR; 甲状腺素结合前清蛋白;thyroxine binding prealbumin;TBPA;转甲状腺素蛋白;甲状腺素运载蛋白;甲状腺素运送蛋白 化学;化学检验项目;化学检验项目类;化学类;化学试验;非刺激耐受型化学检验项目;非刺激耐受型化学检验项目类;非刺激耐受型化学试验;非刺激耐受型化学试验类 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 时刻;随机;随意;瞬间 甲状腺素视黄质运载蛋白（TTR、甲状腺素结合前清蛋白、TBPA、转甲状腺素蛋白、甲状腺素运载蛋白、甲状腺素运送蛋白） - 甲状腺素视黄质运载蛋白（TTR、甲状腺素结合前清蛋白、TBPA、转甲状腺素蛋白、甲状腺素运载蛋白、甲状腺素运送蛋白）峰值 2 甲状腺素视黄质运载蛋白（TTR、甲状腺素结合前清蛋白、TBPA、转甲状腺素蛋白、甲状腺素运载蛋白、甲状腺素运送蛋白）峰值 2 血;血液 质量差（差值、差异、差别、差额、区别）;重量差值;重量差

Example Units

Unit Source
u Example UCUM Units

94863-8 Transthyretin width at half peak height [Mass] in Blood

Part Descriptions

LP418391-1   Transthyretin width at half peak height
The width of the transthyretin peak at half of the maximum height on a mass spectrum. Source: Regenstrief LOINC

Fully-Specified Name

Component
Transthyretin width at half peak height
Property
Mass
Time
Pt
System
Bld
Scale
Qn
Method

Basic Attributes

Class
CHEM
Type
Laboratory
First Released
Version 2.68
Last Updated
Version 2.68 (ADD)
Order vs. Observation
Observation

Member of these Panels

LOINC Long Common Name
94864-6 Transthyretin-associated familial amyloidosis panel - Blood

Language Variants Get Info

Tag Language Translation
el-GR Greek (Greece) Πλάτος τρανσθυρετίνης στο μισό του ύψους κορυφής:Mass:Pt:Αίμα:Qn:
Synonyms: Mass Πλάτος Πλάτος τρανσθυρετίνης στο μισό του ύψους κορυφής Τρανσθυρετίνη Ύψος
es-MX Spanish (Mexico) Ancho de transtiretina a la mitad de la altura del pico:Masa:Punto temporal:Sangre:Cuantitativo:
es-ES Spanish (Spain) Ancho de transtiretina a la mitad de la altura del pico:Masa:Punto temporal:Sangre:Qn:
Synonyms: Cuantitativo
fr-FR French (France) Transthyrétine amplitude à la moitié du pic:Masse:Ponctuel:Sang:Numérique:
it-IT Italian (Italy) Transtiretina, larghezza a metà altezza del picco:Massa:Pt:Sangue:Qn:
Synonyms: Chimica Punto nel tempo (episodio) Sangue
pl-PL Polish (Poland) Szerokość piku transtyretyny w połowie maksymalnej wysokości na widmie masowym.:masa:punkt w czasie:krew:ilościowy:
Synonyms: Szerokość piku transtyretyny w połowie maksymalnej wysokości na widmie masowym.
zh-CN Chinese (China) 甲状腺素视黄质运载蛋白半高宽:质量:时间点:全血:定量型:
Synonyms: TTR; 甲状腺素结合前清蛋白;thyroxine binding prealbumin;TBPA;转甲状腺素蛋白;甲状腺素运载蛋白;甲状腺素运送蛋白 化学;化学检验项目;化学检验项目类;化学类;化学试验;非刺激耐受型化学检验项目;非刺激耐受型化学检验项目类;非刺激耐受型化学试验;非刺激耐受型化学试验类 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 宽 时刻;随机;随意;瞬间 甲状腺素视黄质运载蛋白（TTR、甲状腺素结合前清蛋白、TBPA、转甲状腺素蛋白、甲状腺素运载蛋白、甲状腺素运送蛋白）半高宽 血;血液 身高;身长;身体高度 重量

Example Units

Unit Source
u Example UCUM Units