9513-3

Cytomegalovirus Ab [Titer] in Serum by Complement fixation

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Part Description

LP14255-1 Cytomegalovirus
Cytomegalovirus is a member of the family Herpesviridae and also known as Human Herpesvirus-5 (HHV-5). It contains a linear double-stranded DNA encased in an icosahedral capsid that is surrounded by a viral envelope. It replicates slowly and may take weeks for the infection to become visible microscopically. Its life cycle includes a lytic and a latent phase. During the lytic phase the cytoskeleton of the infected cell is disrupted and becomes very large. The enlarged cell eludes detection by natural killer (NK) cells by encoding UL16. UL16 is a protein that binds to the ligand NDG2D which is a surface receptor on NK cells and, when blocked, prevents the CMV infected cell from apoptotic signaling to NK cells to destroy it.https://pedclerk.bsd.uchicago.edu/page/cytomegalovirus-cmv In the US one in three children are infected by CMV by the age of five and over half of adults are infected by age 40. Infection with CMV is mostly asymptomatic. Symptoms when present include fever, sore throat, fatigue, swollen glands. CMV can occasionally lead to mononucleosis or hepatitis. Immunocompromised patients experience much more acute symptoms that can affect the eyes, lungs, liver, esophagus, stomach, and intestines. For babies born with CMV, involvement with the brain, spleen, lung, liver can occur. In addition, there may be growth problems and hearing loss which is the most common symptom in congenital CMV infection. CMV is transmitted in urine, saliva, blood, tears, semen and breast milk by direct contact. Normally no treatment is necessary, but for severe cases medication is available.https://www.cdc.gov/cmv/overview.html Source: Regenstrief LOINC

LOINC Names Get Info

Fully-Specified Name: Cytomegalovirus Ab:Titr:Pt:Ser:SemiQn:Comp fix
Long Common Name: Cytomegalovirus Ab [Titer] in Serum by Complement fixation
Short Name: CMV Ab Titr Ser CF
Display Name: CMV Ab CF (S) [Titer]
Consumer Name Alpha Get Info: Cytomegalovirus (CMV) antibody, Blood

Part Model Get Info

Component
Cytomegalovirus Ab
LP37878-3
- Analyte
  Cytomegalovirus Ab
  LP37878-3
  - Component Numerator
    Cytomegalovirus Ab
    LP37878-3
    - Component Numerator Core
      Cytomegalovirus
      LP14255-1
    - Component Numerator Core Suffix
      Ab
      LP20667-9
  - Component Denominator
    NULL
    - Component Denominator Core
      NULL
    - Component Denominator Core Suffix
      NULL
- Challenge
  NULL
- Adjustment
  NULL
- Count
  NULL
Property
Titr
LP6881-9
Time
Pt
LP6960-1
- Time Core
  Pt
  LP6960-1
- Time Modifier
  NULL
System
Ser
LP7567-3
- System Core
  Ser
  LP7567-3
- Super System
  NULL
Scale
SemiQn
LP436123-6
Method
Comp fix
LP6176-4

Basic Attributes

Class: MICRO
Type: Laboratory
First Released: Version 1.0i
Last Updated: Version 2.75 (MAJ)
Order vs. Observation: Both

Member of these Panels

LOINC	Long Common Name
54037-7	HEDIS 2009 panel
57820-3	HEDIS 2010 panel
60442-1	HEDIS 2011 panel
67767-4	HEDIS 2012 panel
72199-3	HEDIS 2013 panel
74234-6	HEDIS 2014 Value Sets
75868-0	HEDIS 2015 Value Sets
79544-3	HEDIS 2016 Value Sets
82955-6	HEDIS 2017 Value Sets
87625-0	HEDIS 2018 Value Sets
90766-7	HEDIS 2019 Value Sets

Language Variants Get Info

Tag	Language	Translation
cs-CZ	Czech (Czechia)	Cytomegalovirus Ab:Arbitrární koncentrace (titr):Časový bod:Sérum:Semikvantitativní:Komplement fixační reakce
de-AT	German (Austria)	Synonyms: CMV-AK Ti. KBR
de-DE	German (Germany)	Cytomegalie-Virus Ak:Titer:Zeitpunkt:Serum:Semiquantitativ:Komplementbindungsreaktion Synonyms: CMV
el-GR	Greek (Greece)	Κυτταρομεγαλοϊός Αντίσωμα:Titr:Pt:Ορός:Ημιποσοτική:Σύνδεση Συμπληρώματος Synonyms: MICRO Pt Titr Αντίσωμα Ημιποσοτική Κυτταρομεγαλοϊός Ορός Σύνδεση Συμπληρώματος
es-AR	Spanish (Argentina)	[anticuerpo anti - ] citomegalovirus [Ac]:factor de dilución (titulación):punto en el tiempo:suero:cuantitativo:fijación del complemento
es-ES	Spanish (Spain)	Citomegalovirus Anticuerpos:Titulo / Factor de dilución:Punto temporal:Suero:Semicuantitativo:Fijación del complemento Synonyms: Semicuantitativo
es-MX	Spanish (Mexico)	Citomegalovirus Ab:Título:Punto temporal:Suero:Cuantitativo:Fijación del complemento
fr-CA	French (Canada)	Cytomégalovirus, Ac:Titre:Temps ponctuel:Sérum:SemiQn:Fixation du complément
fr-FR	French (France)	Cytomégalovirus Ac:Titre:Ponctuel:Sérum:Semi-Quantitatif:Fixation du complément
it-IT	Italian (Italy)	Citomegalovirus Ab:Titr:Pt:Siero:SemiQn:Fissazione complemento Synonyms: anticorpo Fissazione del complemento Microbiologia Punto nel tempo (episodio) Siero Titolo
ko-KR	Korean (Korea, Republic Of)	거대세포바이러스 항체:역가:검사시점:혈청:정량:보체결합반응
nl-NL	Dutch (Netherlands)	Cytomegalovirus As:titer:moment:serum:semikwantitatief:complementfixatie Synonyms: antistof; antilichaam
pl-PL	Polish (Poland)	Wirus cytomegalii Ab:miano:punkt w czasie:surowica:półilościowy:test wiązania dopełniacza Synonyms: Cytomegalowirus Przecwciała do cytomegalowirusa
pt-BR	Portuguese (Brazil)	Citomegalovírus Ac:Título:Pt:Soro:Qn:Fixação do complemento Synonyms: ; CMV; Cytomgal; Cytomegalo virus; Dilution factor; Titer; Titre; Ttr; Titered; Point in time; Random; Serum; SR; Quantitative; QNT; Quant; Quan; CF; Complement fixation; Compfix; Antibodies; Autoantibody; Antibody; Autoantibodies; Antby; Acy; Anti; Microbiology
zh-CN	Chinese (China)	巨细胞病毒抗体:滴定度:时间点:血清:半定量型:补体结合试验 Synonyms: Ab;自身抗体 CMV Ab CMV 抗体 CMV;涎腺病毒;细胞巨化病毒;细胞肥大病毒巨细胞病毒 Ab 微生物学;微生物学试验;微生物学试验（培养、DNA、抗原及抗体）效价;滴定浓度;滴定率;滴定量;滴度;稀释倍数;稀释因子;稀释系数时刻;随机;随意;瞬间补体固定;补体固定试验;补体结合;补体结合反应

Example Units

Unit	Source
titer	REGENSTRIEF
{titer}	Example UCUM Units

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LOINC Copyright

Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.