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Term Description

The measurement of CD107a/b expression on the cell surface of CD8+ cells is performed to identify degranulated T cells. PMID: 15603439

Part Descriptions

LP100021-7   Cells.CD3+CD8+
HIV infection decreases the number of CD3+ CD4+ lymphocytes (also called CD4 T cells or T4 helper cells) while increasing (momentarily) the numbers of CD3+CD8+ lymphocytes (called CD8 T lymphocytes or cytotoxic T cells). Thus the ratio of CD4/CD8 lymphocytes is decreased. These counts are used for prognostic purposes and to guide in the retroviral therapy. CDC has emphasized since 1997 that the number of CD3+ lymphocytes is necessary in addition to the number of CD4+ cells to reliably identify the T4 helper cells and the number of CD8+ cells. Laboratory reports that include only CD4 or only CD8 in their nomenclature are most likely really measuring CD3+CD4+ cells and CD3+CD8+ cells, respectively. Source: Regenstrief Help

LP17729-2   CD8
Found on T-suppressor/cytotoxic cells and some Natural Killer cells; Associated with some mature T-cell neoplasms; Large granular lymphocytosis Source: Regenstrief LOINC

LOINC Names Get Info

Fully-Specified Name
Cells.CD8.PMA+ionomycin stimulated CD107a+b expressing/Cells.CD3+CD8+:NFr:Pt:Bld:Qn:Flow cytometry
Long Common Name
PMA+ionomycin stimulated CD107a+b expressing CD8 cells/CD3+CD8+ (T8 suppressor cells) cells in Blood by Flow cytometry (FC)
Short Name
CD107ab CD8/CD3+CD8+ NFr Bld FC
Display Name
PMA+ionomycin stimulated CD107a+b expressing CD8 cells/CD3+CD8+ (T8 suppressor cells) cells FC (Bld)
Consumer Name Alpha Get Info
PMA+ionomycin stimulated CD107a+b expressing CD8 cells/CD3+CD8+ (T8 Suppressor Cells) Cells, Blood

Part Model Get Info

  • Component
    Cells.CD8.PMA+ionomycin stimulated CD107a+b expressing/Cells.CD3+CD8+
    LP445300-9
    • Analyte
      Cells.CD8.PMA+ionomycin stimulated CD107a+b expressing/Cells.CD3+CD8+
      LP445300-9
      • Component Numerator
        Cells.CD8.PMA+ionomycin stimulated CD107a+b expressing
        LP418208-7
        • Component Numerator Core
          Cells.CD8.PMA+ionomycin stimulated CD107a+b expressing
          LP418208-7
        • Component Numerator Core Suffix
          NULL
           
      • Component Denominator
        Cells.CD3+CD8+
        LP100021-7
        • Component Denominator Core
          Cells.CD3+CD8+
          LP100021-7
        • Component Denominator Core Suffix
          NULL
           
    • Challenge
      NULL
       
    • Adjustment
      NULL
       
    • Count
      NULL
       
  • Property
    NFr
    LP6838-9
  • Time
    Pt
    LP6960-1
  • System
    Bld
    LP7057-5
    • System Core
      Bld
      LP7057-5
    • Super System
      NULL
       
  • Scale
    Qn
    LP7753-9
  • Method
    Flow cytometry
    LP6274-7

Basic Attributes

Class
CELLMARK
Type
Laboratory
First Released
Version 2.68
Last Updated
Version 2.79 (NAM)
Change Reason
Release 2.79: COMPONENT: Triggered by Coll w SCT: This is a specific fraction case where the denominator is percentage or /100. Because the logic is that the percentage piece is captured by Property: NFr (Numeric Fraction), and by Unit: %, therefore, it is redundant to include "100" in the component;
Order vs. Observation
Observation

Member of these Panels

LOINCLong Common Name
95184-8Cytomegalovirus T-cell immunodeficiency panel - Blood by Flow cytometry (FC)

Language Variants Get Info

TagLanguageTranslation
cs-CZCzech (Czechia)Buňky CD8 PMA+ionomycinem stimulované CD107a+b exprimující/100 buněk CD3+CD8+:Početní podíl:Časový bod:Krev:Kvantitativní:Průtoková cytometrie
el-GRGreek (Greece)Κύτταρα.CD8.διεγερμένο από PMA+ιονομυκίνη με έκφραση του CD107a+b/Κύτταρα.CD3+CD8+:NFr:Pt:Αίμα:Qn:Κυτταρομετρία ροής
Synonyms: B CD3 CD8 CELLMARK NFr Pt Qn Αίμα Κύτταρα Κύτταρα.CD3 Κύτταρα.CD3+CD8+ Κύτταρα.CD8 Κύτταρα.CD8.διεγερμένο από PMA+ιονομυκίνη με έκφραση του CD107a+b Κυτταρομετρία ροής
es-ESSpanish (Spain)Expresión de CD107a+b en células CD8 estimulado por PMA+ionomicina/Células CD3+CD8+:Fracción numérica:Punto temporal:Sangre:Qn:Citometria de flujo (FC)
Synonyms: Cuantitativo
es-MXSpanish (Mexico)CD107a + b estimulado con ionomicina con PMA + que expresan células CD8 / 100 células CD3 + CD8 +:Fracción numérica:Punto temporal:Sangre:Cuantitativo:Citometría de flujo (FC)
fr-FRFrench (France)CD8 expression CD107a+b stimulé par PMA+ionomycine/CD3+CD8+:Fraction de nombres:Ponctuel:Sang:Numérique:Cytométrie de flux
it-ITItalian (Italy)Cellule.CD8.PMA+ ionomicina stimolata CD107a+b espressa/Cellule.CD3+CD8+:NFr:Pt:Sangue:Qn:Citometria a flusso
Synonyms: Cellule CD3 Cellule CD3+CD8+ Cellule CD3+CD8+ (cellule soppressore T8) Cellule CD8 Citometria a flusso (FC) Frazione numerica Modelli di superficie cellulare PMA+ ionomicina stimolata - cellule CD8 CD107a+b espresse Punto nel tempo (episodio) Sangue
nl-NLDutch (Netherlands)PMA + ionomycinegestimuleerde CD107a+b-positieve CD8-cellen/cellen.CD3+CD8+:getalsfractie:moment:bloed:kwantitatief:flowcytometrie
pl-PLPolish (Poland)Komórki.CD8.Stymulowana PMA+jonomycyną ekspresja CD107a+b/komórki CD3+ CD8+:frakcja liczbowa:punkt w czasie:krew:ilościowy:cytometria przepływowa (FC)
Synonyms: CD8 Komórki CD3+CD8+ Komórki CD8 Komórki CD8 Stymulowana PMA+jonomycyną ekspresja CD107a+b
zh-CNChinese (China)细胞.CD8.PMA+离子霉素刺激性 CD107a+b 表达型/细胞.CD3+CD8+:计数型分数:时间点:全血:定量型:流式细胞测量术
Synonyms: B 型 CD3+CD8+细胞 CD3细胞 CD8细胞 LAMP-1 Leu2 Leu-2 Leu4;Leu-4;T3 T8 T-8 Tsuppressor 动态 发现于 抑制性 T-细胞/细胞毒性 T-细胞、一些 NK 细胞之上。与一些成熟 T-细胞肿瘤和大颗粒淋巴细胞增多症相关 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 抑制性 T 细胞 抑制性 T-细胞 数量型分数;数量或计数型分数;数量型分数或计数型分数 时刻;随机;随意;瞬间 流 流式细胞光度计;流式细胞测量术（Flow Cytometry，FC）;流式细胞计 溶酶体相关膜蛋白 1 溶酶体相关膜蛋白 1（Lysosome-associated membrane-protein 1，LAMP-1） 细胞.CD8.PMA（佛波醇 12-肉豆蔻酸酯 13-乙酸酯、佛波酯）+离子霉素刺激性 CD107a+b 表达型 细胞含量;细胞性;细胞性质;细胞构成;细胞类 细胞标志物 血;血液

Example Units

UnitSource
%Example UCUM Units

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CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=95203-6