Version 2.78

Term Description

The detection & differentiation of HIV-1 and HIV-2 antibodies, also known as third generation testing, in serum or plasma specimens by immunoassay methods. Testing is performed as an additional, more specific test to confirm the presence of HIV-1 and HIV-2 antibodies found by screening procedures.
Source: Regenstrief LOINC

Part Description

LP36650-7   HIV 1 & 2
Human immunodeficiency virus (HIV) is categorized into two types, HIV-1 and HIV-2. Worldwide, most HIV infections are HIV-1, whereas HIV-2 largely has been confined to persons in or from West Africa (1,2). HIV-1 and HIV-2 have the same routes of transmission, and both can cause acquired immunodeficiency syndrome (AIDS) (3); however, HIV-2 infections should be differentiated from HIV-1 infections because they are less likely to cause AIDS and their clinical management differs (4,5). CDC's current surveillance case definition for HIV infection applies to both variants of HIV (6) but lacks criteria for differentiating between HIV-1 and HIV-2.

To enumerate and describe HIV-2 cases reported in the United States, a working case definition was developed. During 1988 through June 2010, a total of 242 HIV-2 cases were reported to CDC. Of these, 166 met the working definition. These HIV-2 cases were concentrated in the Northeast (66%, including 46% in New York City) and occurred primarily among persons born in West Africa (81%). Ninety-seven of the HIV-2 cases also had a positive HIV-1 immunoblot antibody test result (e.g., Western blot). Immunoblot antibody tests currently used to confirm HIV reactive screening tests do not contain reagents specific to HIV-2 and thus are not reliable for identification of HIV-2 infections (7). Additional testing specific to HIV-2 should be considered if HIV-1 test results are atypical or inconsistent with clinical findings, especially for persons from West Africa. If an HIV case is reported to the health department but subsequently identified as HIV-2, health-care providers should update the case report to reflect the correct type. As of June 2012, the Bio-Rad Multispot HIV-1/HIV-2 Rapid Test is FDA approved for distinguishing HIV1 from HIV2. Source: Centers for Disease Control and Prevention, LV Torian, et al. HIV-2 Infection Surveillance -- United States, 1987-2009. Morbidity and Mortality Weekly Report 60(29);985-988. July 29, 2011.

Fully-Specified Name

Component
HIV 1 & 2 Ab
Property
Prid
Time
Pt
System
Ser/Plas
Scale
Nom
Method
IA

Additional Names

Short Name
HIV 1 & 2 Ab SerPl IA
Display Name
HIV 1 and 2 Ab IA Nom
Consumer Name Alpha Get Info
HIV 1 and 2 antibody, Blood

Example Answer List: LL5632-6

Source: Avioq
Answer Code Score Answer ID
HIV Negative LA24959-1
HIV-1 Indeterminate LA24952-6
HIV-1 Positive LA24955-9
HIV-2 Positive LA24956-7
HIV-1 Positive with HIV-2 cross-reactivity LA31133-4
HIV-2 Positive with HIV-1 cross-reactivity LA24957-5

Basic Attributes

Class
MICRO
Type
Laboratory
First Released
Version 2.69
Last Updated
Version 2.69
Order vs. Observation
Both

Member of these Panels

LOINC Long Common Name
95523-7 HIV 1 and 2 Ab panel - Serum or Plasma by Immunoassay

Language Variants Get Info

Tag Language Translation
es-ES Spanish (Spain) HIV 1 y 2 Anticuerpos:Presencia o identidad:Punto temporal:Suero o Plasma:Nom:IA
es-MX Spanish (Mexico) VIH 1 y 2 Ab:Presencia o identidad:Punto temporal:Suero o Plasma:Nominal:Inmunoensayo
fr-FR French (France) VIH-1 et VIH-2 Ac:Identification:Ponctuel:Sérum/Plasma:Résultat nominal:Immunoanalyse
fr-BE French (Belgium) VIH 1 & 2 Ac:Présence ou identité:Temps ponctuel:Sérum/Plasma:Nominal:IA
Synonyms: Anticorps HIV HIV 1 HIV 1&2 HIV 1+2
fr-CA French (Canada) VIH 1 & 2, Ac:Présence ou identité:Temps ponctuel:Sérum/Plasma:Nominal:IA
it-IT Italian (Italy) HIV 1 & 2 Ab:Prid:Pt:Siero/Plasma:Nom:IA
Synonyms: anticorpo Immunoassay Microbiologia Plasma Presenza o Identità Punto nel tempo (episodio) Siero Siero o Plasma
nl-NL Dutch (Netherlands) HIV 1 & 2 As:identificator:moment:serum of plasma:nominaal:immunoassay
Synonyms: antistof; antilichaam IA
pl-PL Polish (Poland) HIV 1 i 2 Ab:wykrycie lub identyfikacja:punkt w czasie:surowica lub osocze:cecha:metoda immunologiczna
Synonyms: Ludzki wirus niedoboru odporności typu 1 Ludzki wirus niedoboru odporności typu 1 i 2 Ludzki wirus niedoboru odporności typu 1+2 Przeciwciała do HIV 1 i 2 Przeciwciała do HIV 1+2
ru-RU Russian (Russian Federation) HIV 1 & 2 Ат:ПрИд:ТчкВрм:Сыв/Плаз:Ном:IA
Synonyms: Антитело ВИЧ ВИЧ 1 ВИЧ 1 и 2 ВИЧ 1+2 Номинальный;Именной Плазма Присутствие или Идентификация Сыворотка Сыворотка или Плазма Точка во времени;Момент
tr-TR Turkish (Turkey) HIV 1 ve 2 Ab:MevcKimlik:Zmlı:Ser/Plaz:Snf:İA
Synonyms: Ak İmmünölçüm, immünoassay
uk-UA Ukrainian (Ukraine) ВІЛ 1 та 2 Антитіла:Наявність або Ідентифікація:МоментЧасу:Сироватка/Плазма:Категорійно:Імуноаналіз
Synonyms: ABS; Aby; AIDS; Antby; Anti; Antibodies; Antibody; Autoantibodies; Autoantibody; EIA; ELFA; ELISA; Enzyme immunoassay; HIV 1 and 2 Ab; HIV type 1; HIV type I; HIV1; HIV1+2; Human immunodeficiency virus; i; IAA; ID; Identity or presence; II; Infectious Disease; InfectiousDisease; MEIA; Microbiology; Nominal; Pl; Plasma; Plsm; Point in time; Random; SerP; SerPl; SerPlas; Serum; Serum or plasma; SR; SUDS
zh-CN Chinese (China) HIV 1 型 与 2 型 抗体:存在与否或特征标识:时间点:血清/血浆:名义型:免疫测定法
Synonyms: Ⅰ Ⅱ Ab;自身抗体 AIDS;AIDS 病毒;人类免疫缺陷病毒;人类免疫缺陷病毒（Human immunodeficiency virus，HIV）;爱滋病;艾滋病;艾滋病病毒;获得性免疫缺陷综合征;获得性免疫缺陷综合征（Acquired Immure Deficiency Syndrome，AIDS，艾滋病） HIV 1 & 2 Ab HIV 1+2 Ab HIV1;HTLV 3;HTLV III;人类免疫缺陷病毒 1 型;人类免疫缺陷病毒 I 型;HIV 1 型（人类免疫缺陷病毒 1 型、人类免疫缺陷病毒 I 型、人免疫缺陷病毒 1 型、人免疫缺陷病毒 I 型、HIV I、HIV I 型、艾滋病病毒 I 型） I II 人类免疫缺陷病毒 1 & 2 型 Ab 人类免疫缺陷病毒 1 & 2 型抗体 人类免疫缺陷病毒 1 与 2 型 Ab 人类免疫缺陷病毒 1 与 2 型;HIV（人类免疫缺陷病毒、人免疫缺陷病毒、艾滋病病毒） 1 型（I 型） 与 2 型（II 型） 人类免疫缺陷病毒 1 与 2 型抗体 人类免疫缺陷病毒 1+2 型 Ab 人类免疫缺陷病毒 1+2 型;HIV 1+2 型（人类免疫缺陷病毒 1+2 型、人类免疫缺陷病毒 I+II 型、人免疫缺陷病毒 1+2 型、人免疫缺陷病毒 I+II 型、HIV I+II、HIV I+II 型、艾滋病病毒 I+II 型） 人类免疫缺陷病毒 1+2 型抗体 免疫测定;免疫分析法;免疫检定法;免疫检定;免疫试验;酶免疫测定法;酶免疫测定;酶免疫分析法;酶免疫检定法;酶免疫检定;酶免疫试验 分类型应答;分类型结果;名义性;名称型;名词型;名词性;标称性;没有自然次序的名义型或分类型应答 存在;存在与否;特征标识;身份;身份标识 微生物学;微生物学试验;微生物学试验（培养、DNA、抗原及抗体） 时刻;随机;随意;瞬间 血清或血浆

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CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=95524-5