95550-0
ABL1 gene c.944C>T [Presence] in Blood or Marrow by Molecular genetics method
Active
Term Description
Detection of the single-point mutation, T315I, in the ABL1 gene within the BCR-ABL1 fusion transcript. Early detection of T315I mutation in patient's with chronic myeloid leukemia (CML) could inform alternative treatment before resistance is detected cytogenetically or before disease progression become evident. Mutations in the kinase domain of the BCR-ABL1 fusion are the leading cause of acquired imatinib resistance. Although mutations have been identified in more than 30 different amino acids, the highest degree of resistance is found to be associated with the T315I mutation.
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- ABL1 gene.c.944C>T
- Property
- PrThr
- Time
- Pt
- System
- Bld/Bone mar
- Scale
- Ord
- Method
- Molgen
Additional Names
- Short Name
- ABL1 c.944C>T Bld/Mar Ql
- Display Name
- ABL1 gene c.944C>T Molgen Ql (Bld/BM)
- Consumer Name Alpha Get Info
- ABL1 gene c.944C>T, Blood Or Bone marrow
Example Answer List: LL360-9
Source: Regenstrief Institute| Answer | Code | Score | Answer ID |
|---|---|---|---|
| PositiveCopyright http://snomed.info/sct ID:10828004 Positive (qualifier value) | LA6576-8 | ||
| NegativeCopyright http://snomed.info/sct ID:260385009 Negative (qualifier value) | LA6577-6 |
Basic Attributes
- Class
- MOLPATH.MUT
- Type
- Laboratory
- First Released
- Version 2.69
- Last Updated
- Version 2.69
- Order vs. Observation
- Both
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| es-ES | Spanish (Spain) | Gen ABL1 c.944C> T: |
| es-MX | Spanish (Mexico) | Gen ABL1 c. 944C> T: |
| fr-FR | French (France) | ABL1 gène.c.944C>T: |
| it-IT | Italian (Italy) | ABL1, gene.c.944C>T: Synonyms: Gene ABL1 c.944C> |
| nl-NL | Dutch (Netherlands) | ABL1-gen.c.944C>T: Synonyms: molgen |
| zh-CN | Chinese (China) | ABL1 基因.c.944C>T: Synonyms: ABL C 型; |
LOINC Terminology Service (API) using HL7® FHIR® Get Info
Requests to this service require a free LOINC username and password. Below is a sample of the possible capabilities. See the LOINC Terminology Service documentation for more information.
- CodeSystem lookup
- https:
//fhir.loinc.org/CodeSystem/$lookup?system=http: //loinc.org&code=95550-0
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LOINC Copyright
Copyright © 2024 Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright