Version 2.78

Part Descriptions

LP207365-0   Ab.Neut
Neutralizing antibodies are antibodies that interfere with the interaction between the virus and its host cell receptor, therefore preventing infectivity. Neutralizing antibodies can be detected using a traditional VNT or other methods such as pseudovirus VNT and surrogate VNT. VNT and pseudovirus VNT use live virus (the actual virus or a recombinant virus that incorporates the viral antigen of interest, respectively) and cell culture to assess the virus-host interaction and whether neutralizing antibodies are present that block that interaction. Surrogate VNT (sVNT) does not use live virus but rather uses purified viral antigen and host cell receptor protein to mimic the same interaction. The sVNT method is currently (2021) represented in LOINC as IA, because it is an immunoassay-based method. Source: Regenstrief LOINC

LP21134-9   Powassan virus
The Powassan virus is a tick-borne encephalitis virus related to the classic TBE flavivirus. This disease had its earliest origins in the town of Powassan, Ontario, found in a young boy who eventually died from it. Powassan virus is transmitted by I.cookei among small mammals in eastern Canada and the United States, where it has been responsible for 20 recognized cases of human disease. Other ticks may transmit the virus in a wider geographic area, and there is some concern that I.scapularis (also called I.dammini ), a competent vector in the laboratory, may become involved as it becomes more prominent in the United States. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Powassan virus

LP6416-4   Neut
In LOINC, the Method "Neut" represents the virus neutralization test (VNT), also called conventional VNT, which is a specific laboratory method that is used primarily for identifying whether neutralizing antibodies for the virus of interest are present in the patient sample. The VNT involves incubating patient serum with the virus of interest, and then inoculating onto cell culture. If neutralizing antibodies are present and the virus is neutralized, the cells will not be infected. If neutralizing antibodies are not present, the virus will infect the cells in the cell culture. PMID: 32170698 This method can also be used to identify specific virus serotypes or strains, by performing separate tests in which serum is incubated with each of the specific virus serotypes or strains of interest. PMID: 169804 Source: Regenstrief LOINC

Fully-Specified Name

Component
Powassan virus Ab.Neut
Property
Titr
Time
Pt
System
XXX
Scale
SemiQn
Method
Neut

Additional Names

Short Name
POWV NAb Titr Spec Nt
Display Name
Powassan virus neut ab Neut test (Specimen) [Titer]
Consumer Name Alpha Get Info
Powassan virus neutralizing antibody, Specimen

Basic Attributes

Class
MICRO
Type
Laboratory
First Released
Version 2.69
Last Updated
Version 2.75
Change Reason
Release 2.72: COMPONENT: Updated "Ab" to "Ab.Neut" since this test is detecting neutralizing antibodies.;
Order vs. Observation
Both

Member of these Groups Get Info

LOINC Group Group Name
LG32767-2 Powassan virus

Language Variants Get Info

Tag Language Translation
es-MX Spanish (Mexico) Virus de Powassan Ab:Título:Punto temporal:XXX:Cuantitativo:Prueba de neutralización
es-ES Spanish (Spain) Virus Powassan Anticuerpos antineutrófilos:Titulo / Factor de dilución:Punto temporal:XXX:Semicuantitativo:Prueba de neutralización
Synonyms: Semicuantitativo
fr-FR French (France) Powassan virus Ac neutralisant:Titre:Ponctuel:Milieux divers:Semi-Quantitatif:Neutralisation
fr-CA French (Canada) Virus Powassan Ac.neut:Titre:Temps ponctuel:XXX:SemiQn:Test de neutralisation
it-IT Italian (Italy) Powassan, virus Ab.Neut:Titr:Pt:XXX:SemiQn:Neut
Synonyms: anticorpo Microbiologia Punto nel tempo (episodio) Test di neutralizzazione Titolo Virus dell''encefalite Powassan
nl-NL Dutch (Netherlands) Powassanvirus As.neutraliserend:titer:moment:XXX:semikwantitatief:neutralisatietest
Synonyms: antistof; antilichaam
pl-PL Polish (Poland) Wirus Powassan Ab.Neutralizujące:miano:punkt w czasie:XXX:półilościowy:test neutralizacji
Synonyms: Przeciwciała do wirusa Powassan Przeciwciała neutralizujące do wirusa Powassan
zh-CN Chinese (China) Powassan 病毒 抗体.中和:滴定度:时间点:XXX:半定量型:中和试验
Synonyms: Ab;自身抗体 Powassan 病毒 Ab POWV POWV Ab POWV 抗体 不明的;其他;将在相应消息内其他部分之中加以详细说明;未作详细说明的;未作说明的;未做说明的标本;未加规定的;未加说明的标本;杂项 中和试验;中和抗体;中和 传染毒;传染毒素;滤过性病原体;病毒类;过滤性病原体 微生物学;微生物学试验;微生物学试验（培养、DNA、抗原及抗体） 效价;滴定浓度;滴定率;滴定量;滴度;稀释倍数;稀释因子;稀释系数 时刻;随机;随意;瞬间

Example Units

Unit Source
{titer} Example UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=95647-4