Version 2.77

Part Description

LP93517-8   Human epididymis protein 4
Human epididymis protein 4 (known as HE4, or as WAP four-disulfide core domain protein 2) is a protein that in humans is encoded by the WFDC2 gene and belongs to the family of whey acidic four-disulfide core (WFDC) proteins. HE4 is overexpressed in both ovarian and endometrial cancers and is an important biomarker that complements CA 125 in discriminating between benign and malignant pelvic masses, monitoring response to treatment, and detecting recurrences of both ovarian and endometrial cancer. The risk of ovarian malignancy algorithm (ROMA) includes CA 125, HE4, and menopausal status to distinguish benign from malignant adnexal masses. HE4 may augment the sensitivity of CA 125 for detecting early-stage ovarian cancer. PMID: 23909069 Source: Regenstrief LOINC, PMID: 23909069

Fully-Specified Name

Component
Human epididymis protein 4
Property
MCnc
Time
Pt
System
Ser/Plas
Scale
Qn
Method

Additional Names

Short Name
HE4 SerPl-mCnc
Display Name
Human epididymis protein 4 [Mass/Vol]
Consumer Name Alpha Get Info
Human epididymis protein 4, Blood

Basic Attributes

Class
CHEM
Type
Laboratory
First Released
Version 2.69
Last Updated
Version 2.69
Order vs. Observation
Both

Member of these Groups Get Info

LOINC Group Group Name
LG51042-6 Human epididymis protein 4|Pt|Ser/Plas

Language Variants Get Info

Tag Language Translation
es-ES Spanish (Spain) Proteína 4 del epidídimo humano:Concentración de masa:Punto temporal:Suero o Plasma:Qn:
Synonyms: Cuantitativo
es-MX Spanish (Mexico) Proteína 4 del epidídimo humano:Concentración de masa:Punto temporal:Suero o Plasma:Cuantitativo:
et-EE Estonian (Estonia) Kasvajaantigeen HE4:MCnc:Pt:S/P:Qn:
Synonyms: Juhuslik Kvantitatiivne Plasma Seerum Seerum või plasma
fr-BE French (Belgium) Protéine 4. épididyne humain:Concentration de masse:Temps ponctuel:Sérum/Plasma:Quantitatif:
fr-CA French (Canada) Protéine 4 épididyme humaine:Concentration de masse:Temps ponctuel:Sérum/Plasma:Quantitatif:
fr-FR French (France) Protéine HE4:Masse/Volume:Ponctuel:Sérum/Plasma:Numérique:
it-IT Italian (Italy) Epididimo umano, proteina 4:MCnc:Pt:Siero/Plasma:Qn:
Synonyms: Chimica Concentrazione di Massa Plasma Proteina 4 dell''epididimo umano Punto nel tempo (episodio) Siero Siero o Plasma
nl-NL Dutch (Netherlands) Humaan epididymis proteïne 4:massa/volume:moment:serum of plasma:kwantitatief:
ru-RU Russian (Russian Federation) Человеческий придаток яичка протеин 4:МассКонц:ТчкВрм:Сыв/Плаз:Колич:
Synonyms: Белок Белок 4 эпидидимиса человека Количественный Массовая концентрация Плазма Сыворотка Сыворотка или Плазма Точка во времени;Момент
tr-TR Turkish (Turkey) Human epididymis protein 4:KütlKons:Zmlı:Ser/Plaz:Kant:
zh-CN Chinese (China) 人附睾蛋白 4:质量浓度:时间点:血清/血浆:定量型:
Synonyms: PR;Prot;成分 - 化学 - 蛋白质类;蛋白;朊;蛋白质类;蛋白质类物质 人类附睾蛋白 4;HE4;Human epididymal protein 4;人附睾上皮分泌蛋白 4;人附睾分泌蛋白 4 化学;化学检验项目;化学检验项目类;化学类;化学试验;非刺激耐受型化学检验项目;非刺激耐受型化学检验项目类;非刺激耐受型化学试验;非刺激耐受型化学试验类 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 时刻;随机;随意;瞬间 水平;浓度;质量浓度(单位体积) 血清或血浆

Example Units

Unit Source
pg/mL Example UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=96044-3